X-shaped DNA potentiates therapeutic efficacy in colitis-associated colon cancer through dual activation of TLR9 and inflammasomes

Resiquimod, a TLR7/8 agonist, promotes differentiation of myeloid-derived suppressor cells into macrophages and dendritic cells

(2014) Moonkyu Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

PPARδ deficiency disrupts hypoxia-mediated tumorigenic potential of colon cancer cells

(2014) Eunshil Jeong et al.   MOLECULAR CARCINOGENESIS

Strange attractors: DAMPs and autophagy link tumor cell death and immunity

(2013) W Hou et al.   Cell Death & Disease

Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2

(2012) So Young Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Effects of TLR Activation on T-Cell Development and Differentiation

(2012) Bo Jin et al.   Clinical & Developmental Immunology

Intracellular Invasion of Orientia tsutsugamushi Activates Inflammasome in ASC-Dependent Manner

(2012) Jung-Eun Koo et al.   PLoS One

The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis

(2011) Md. Hasan Zaki et al.   CANCER CELL

Intrinsic and Extrinsic Regulation of Innate Immune Receptors

(2011) Eunshil Jeong et al.   YONSEI MEDICAL JOURNAL

Biodegradable CpG DNA hydrogels for sustained delivery of doxorubicin and immunostimulatory signals in tumor-bearing mice

(2010) Makiya Nishikawa et al.   BIOMATERIALS

Akt Contributes to Activation of the TRIF-Dependent Signaling Pathways of TLRs by Interacting with TANK-Binding Kinase 1

(2010) S. M. Joung et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

(2010) T. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor

(2009) So Young Kim et al.   IMMUNOLOGY

Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice

(2009) Yumiko Mizuno et al.   JOURNAL OF CONTROLLED RELEASE

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Modulation of pattern recognition receptor-mediated inflammation and risk of chronic diseases by dietary fatty acids

(2009) Joo Y Lee et al.   NUTRITION REVIEWS

Immune Therapy for Cancer

(2008) Michael Dougan et al.   Annual Review of Immunology

Targeting Toll-Like Receptor 9 with CpG Oligodeoxynucleotides Enhances Anti-Tumor Responses of Peripheral Blood Mononuclear Cells from Human Lung Cancer Patients

(2008) Tao Ren et al.   CANCER INVESTIGATION

Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation

(2008) Makiya Nishikawa et al.   IMMUNOLOGY

Toll-like receptor 9 (TLR9) agonists in the treatment of cancer

(2008) A M Krieg   ONCOGENE