Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity

TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells

(2012) Luciana R Gomes et al.   BMC CANCER

Biological Responses to TGF-  in the Mammary Epithelium Show a Complex Dependency on Smad3 Gene Dosage with Important Implications for Tumor Progression

(2012) E. A. Kohn et al.   MOLECULAR CANCER RESEARCH

Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo

(2012) R B Luwor et al.   ONCOGENE

Proteomic Analyses Reveal High Expression of Decorin and Endoplasmin (HSP90B1) Are Associated with Breast Cancer Metastasis and Decreased Survival

(2012) Thomas R. Cawthorn et al.   PLoS One

Mechanisms of cancer cell metastasis to the bone: a multistep process

(2011) Lalit R Patel et al.   Future Oncology

New reagents for improvedin vitroandin vivoexamination of TGF-β signalling

(2011) Rodney B. Luwor et al.   GROWTH FACTORS

Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

(2011) J A Knauf et al.   ONCOGENE

Early tumor dissemination, but late metastasis: insights into tumor dormancy

(2010) Martin Röcken   JOURNAL OF CLINICAL INVESTIGATION

Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models

(2010) H. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmentally regulated SMAD2 and SMAD3 utilization directs activin signaling outcomes

(2009) Catherine Itman et al.   DEVELOPMENTAL DYNAMICS

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis

(2009) Manav Korpal et al.   NATURE MEDICINE

Silencing of Transforming Growth Factor- 1 In situ by RNA Interference for Breast Cancer: Implications for Proliferation and Migration In vitro and Metastasis In vivo

(2008) L. D. Moore et al.   CLINICAL CANCER RESEARCH