Article
Neurosciences
Jason Stretton, Susanne Schweizer, Tim Dalgleish
Summary: Aging is associated with a bias in attention and memories toward positive
and away from negative emotional content. In addition, emotion regulation appears to
improve with age, despite concomitant widespread cognitive decline coupled with gray
matter volume loss in cortical and subcortical regions thought to subserve emotion
regulation.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Hiroko Tanabe, Kota Yamamoto
Summary: This study constructed models of female gait attractiveness using gait kinematics and physique factors as explanatory variables. The results deepened our understanding of mechanisms behind nonverbal interpersonal cognition through physical movement, and brought us closer to realizing the artificial generation of attractive gait motions.
SCIENTIFIC REPORTS
(2023)
Article
Psychology, Multidisciplinary
Hang Bing, Bakhtiar Sadjadi, Maryam Afzali, Jalil Fathi
Summary: This study examined the predictive roles of emotion regulation and teacher self-efficacy in teacher burnout in the Chinese English as a Foreign Language context. The results showed that teacher self-efficacy is a stronger predictor of teacher burnout compared to emotion regulation.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Medicine, General & Internal
Tanja Maier, Melanie Kugelmann, Dae-Sup Rhee, Sebastian Brill, Harald Guendel, Benedikt Friemert, Horst-Peter Becker, Christiane Waller, Manuela Rappel
Summary: This study aimed to develop a Global Stress Index (GSI) by combining individual measures of acute and chronic stress from childhood to adult life, providing a valuable and individual stress profile for soldiers that could potentially complement classical cardiovascular risk factors. The hierarchical multilevel model revealed a fair fit, with the highest order being the GSI factor, followed by direct loading of stress, HADS, and CTQ variables on the GSI in the second level, and implementation of six CTQ subscales in the third level.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Mahboubeh Moradi Siah Afshadi, Shole Amiri, Hooshang Talebi
Summary: Although executive functions have been considered the main correlation of ADHD, few studies have examined the impact of EFs on ADHD symptoms in ADHD samples. This study aimed to examine the structure of EFs on ADHD students in a hypothetical model. After careful screening, 211 university students diagnosed with ADHD were selected. The results showed that emotion regulation and intrinsic motivation had significant direct and indirect effects on ADHD subscales, with time management mediating the relationship between motivation, emotion regulation, and ADHD.
CURRENT PSYCHOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
Edgar C. Merkle, Ellen Fitzsimmons, James Uanhoro, Ben Goodrich
Summary: This paper describes a general, efficient approach to Bayesian SEM estimation in Stan, contrasting it with previous implementations in R package blavaan. Practical comparisons under multiple scenarios show that the new approach is clearly better, and discussions on possible extensions to other models of interest to psychometricians are provided.
JOURNAL OF STATISTICAL SOFTWARE
(2021)
Article
Genetics & Heredity
Jianying Li, Pierre R. Bushel, Lin Lin, Kevin Day, Tianyuan Wang, Francesco J. DeMayo, San-Pin Wu, Jian-Liang Li
Summary: This article discusses the use of structural equation modeling in analyzing gene expression data to estimate molecular activities of regulators and understand complex human biological systems. The results suggest that this approach can help infer potential gene interactions and explore the clinical relevance of diseases.
FRONTIERS IN GENETICS
(2021)
Article
Engineering, Multidisciplinary
Clement Vella, Serge Prudhomme
Summary: In this paper, a Proper Generalized Decomposition (PGD) approach for problems in linear elastodynamics is proposed. The novelty lies in the development of weak formulations based on Lagrangian and Hamiltonian Mechanics, aiming to devise numerically stable and energy conservative methods. The Galerkin-based version of PGD is considered and it is shown that the PGD solver based on the Hamiltonian formulation offers better stability and energy conservation properties compared to the Lagrangian formulation. The performance of the two formulations is illustrated and compared on several numerical examples.
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
(2022)
Article
Psychiatry
Patrizia Velotti, Guyonne Rogier, Sara Beomonte Zobel, Rosetta Castellano, Renata Tambelli
Summary: The study confirmed that increased levels of loneliness experienced during the COVID-19 pandemic predicted internalizing symptoms such as depression, anxiety, and stress. Additionally, emotion dysregulation levels partially mediated the longitudinal relationship between loneliness and depression and stress.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Business
Alireza Amini, Moslem Alimohammadlou
Summary: ISM is an interactive process that may suffer from reliance on intuition and judgment. To enhance this method, ESM is proposed, offering a statistically verifiable framework and a graphical, hierarchical, and intuitive model.
JOURNAL OF MANAGEMENT ANALYTICS
(2021)
Article
Public, Environmental & Occupational Health
Jinsong Geng, Xiaowei Chen, Jianwei Shi, Haini Bao, Qian Chen, Hao Yu
Summary: The study found that patient satisfaction with health insurance programs is influenced by factors such as patients' awareness of insurance policies, fulfillment of insurance benefits expectations, and perceived value of insurance coverage. Urban Employee Basic Medical Insurance enrollees had a higher degree of satisfaction with insurance compared to Urban-Rural Resident Basic Medical Insurance enrollees.
Article
Multidisciplinary Sciences
Kensuke Joh, Takashi Nakazato, Akinori Hashiguchi, Akira Shimizu, Ritsuko Katafuchi, Hideo Okonogi, Kentaro Koike, Keita Hirano, Nobuo Tsuboi, Tetsuya Kawamura, Takashi Yokoo, Ichiei Narita, Yusuke Suzuki
Summary: This study used structural equation modeling (SEM) to analyze the direct and indirect effects of histological variables on renal functional decline in patients with immunoglobulin A nephropathy (IgAN). The results showed that tubular atrophy/interstitial fibrosis had a direct promoting effect on renal functional decline, while endocapillary hypercellularity and active crescent had an indirect weakening effect via steroid therapy with/without tonsillectomy. Segmental sclerosis had an indirect weakening effect via estimated glomerular filtration rate, and mesangial hypercellularity had an accelerating indirect effect on renal functional decline via proteinuria.
Article
Engineering, Biomedical
Hee Ho Park, Hyelim Kim, Han Sol Lee, Eun U. Seo, Ji-Eun Kim, Jee-Hyun Lee, Yong-Hyeon Mun, So-Yeol Yoo, Jiseon An, Mi-Young Yun, Nae-Won Kang, Dae-Duk Kim, Dong Hee Na, Kyung Soo Hong, Jong Geol Jang, June Hong Ahn, Jong-Sup Bae, Gyu Yong Song, Jae-Young Lee, Hong Nam Kim, Wonhwa Lee
Summary: This study proposes the use of drug-loaded albumin nanoparticles as a therapeutic agent for severe SARS-CoV-2 patients. The engineered blood vessel model confirmed the effectiveness of the drugs in suppressing blood clot formation and vascular inflammation. Animal model experiments demonstrated that the drugs improved survival rates by reducing tissue damage and cytokine storm.
Article
Biochemistry & Molecular Biology
Kento Nishida, Hiroshi Watanabe, Ryota Murata, Kai Tokumaru, Rui Fujimura, Shun Oshiro, Taisei Nagasaki, Masako Miyahisa, Yuto Hiramoto, Hiroto Nosaki, Tadashi Imafuku, Hitoshi Maeda, Masafumi Fukagawa, Toru Maruyama
Summary: The study shows that HSA-Trx has the potential to inhibit the transition from AKI to CKD by accelerating renal function recovery, reducing renal fibrosis, suppressing oxidative stress and inflammation, and ameliorating kidney injury.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Ying Chai, Xiufeng Liang, Yi Liu
Summary: This study aims to establish a systematic approach to analyzing the factors that influence the construction quality of prefabricated buildings and their interrelationships. A questionnaire was issued based on a literature review, and a model of the factors that influence the construction quality of fabricated buildings was established using structural equation modeling. Results showed that construction organization and management have a significant impact on building quality, prefabricated components, and the construction process, and identified core factors influencing the quality of prefabricated construction.
APPLIED SCIENCES-BASEL
(2023)
Article
Psychology, Developmental
Liang-Jen Wang, Ying-Hua Huang, Wen-Jiun Chou, Sheng-Yu Lee, Hsin-Yu Chang, Chih-Cheng Chen, How-Ran Chao
Summary: Abnormal growth hormones and thyroid function may contribute to the pathophysiology of ADHD. Endocrine-disrupting chemicals (EDCs) such as phthalates and bisphenol-A (BPA) may affect the endocrine system. This study found that ADHD patients had lower levels of IGF-1 and higher levels of certain EDCs compared to healthy controls. The findings suggest that MEHP exposure may be associated with decreased IGF-1 levels and increased risk of ADHD.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
I-Chun Chen, Pai-Wei Lee, Liang-Jen Wang, Chih-Hao Chang, Cheng-Hsiu Lin, Li-Wei Ko
Summary: This study investigated the discriminative validity of various single or combined measurements of EEG data, K-CPT, and DBDRS to differentiate preschool children with ADHD from those with TD. The combination of DBDRS, K-CPT, and specific EEG data provided the best probability scores and discriminative validity to identify preschool children with ADHD. Multi-method and multi-informant evaluations should be emphasized in clinical diagnosis of preschool ADHD.
JOURNAL OF ATTENTION DISORDERS
(2022)
Article
Psychiatry
Liang-Jen Wang, Yu-Chi Huang, Pao-Yen Lin, Yu Lee, Chi-Fa Hung, Su-Ting Hsu, Lien-Hung Huang, Sung-Chou Li
Summary: This study identified four novel protein markers (BST1, ITIH5, SDPR, and OSCAR) of schizophrenia, with BST-1 serving as a serum protein biomarker involved in neutrophil infiltration. The anti-inflammation nature of BST1 was highlighted, showing its potential significance in schizophrenia research. The machine learning algorithm combining BST1, ITIH5, and OSCAR levels developed a prediction model of schizophrenia with an auROC value of 0.78.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2022)
Letter
Endocrinology & Metabolism
I-Wen Wu, Tsung-Hsien Tsai, Chi-Jen Lo, Yi-Ju Chou, Chi-Hsiao Yeh, Mei-Ling Cheng, Chi-Chun Lai, Huey-Kang Sytwu, Ting-Fen Tsai
Article
Education & Educational Research
Ji-Tseng Fang, Shih-Ying Chen, Ya-Chung Tian, Chien-Hung Lee, I-Wen Wu, Chen-Yi Kao, Chung-Chih Lin, Woung-Ru Tang
Summary: This study demonstrated that online ESRD communication skills training can enhance the truth-telling confidence of healthcare personnel, though it is unclear whether this improvement is due to the content of the training or its online delivery. While face-to-face training may be unsuitable during pandemics, online training remains an indispensable tool. Future intervention studies should focus on designing interactive modules and controlling for instructional methods.
BMC MEDICAL EDUCATION
(2022)
Article
Public, Environmental & Occupational Health
Shao-Chi Chu, Po-Hsi Wang, Kuan-Ying Lu, Chia-Chun Ko, Yun-Hsuan She, Chin-Chan Lee, I-Wen Wu, Chiao-Yin Sun, Heng-Jung Hsu, Heng-Chih Pan
Summary: Obesity and metabolic syndrome are risk factors for chronic kidney disease. This study found that the combination of obesity and metabolic syndrome, known as metabolic body composition status (MBCS), is associated with rapid kidney function decline (RKFD), particularly in older adults. Metabolically unhealthy normal weight and metabolically unhealthy overweight were identified as risk factors for RKFD.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Psychology, Developmental
Liang-Jen Wang, Sung-Chou Li, Yuan-Ming Yeh, Sheng-Yu Lee, Ho-Chang Kuo, Chia-Yu Yang
Summary: This study used high-throughput sequencing to explore the dysbiosis of the gut mycobiome in children with ADHD. The results showed that ADHD patients had abnormal fungal community composition and increased abundance of Candida, especially Candida albicans. The in vitro cell assay also demonstrated that C. albicans secretions enhanced intestinal permeability.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Immunology
Liang-Jen Wang, Ching-Shu Tsai, Wen-Jiun Chou, Chia-Jung Li, Sheng-Yu Lee, Yi-Chun Chen, I. -Chun Lin
Summary: This longitudinal study compared adverse outcomes after SARS-CoV-2 vaccination in children with neurodevelopmental disorders (ND) and healthy control children. The results showed that children with ND had a higher likelihood of subsequent outpatient department or emergency department visits, especially pediatric neurology visits, after the first dose of vaccination compared to the control group. However, only a small proportion of children visited the outpatient department or emergency department due to adverse vaccination-related effects. Overall, the study concluded that specific ND diagnosis or medication use did not significantly increase the risk of adverse effects of SARS-CoV-2 vaccination, and children with ND can be reassured that the vaccination is safe.
Article
Food Science & Technology
Chia-Jung Li, Ling-Sai Chang, Mindy Ming-Huey Guo, Liang-Jen Wang, Ho-Chang Kuo
Summary: This study aimed to investigate the role of vitamin D in children with coexisting allergic diseases, particularly in terms of sex differences, and to explore the behavioral profiles of these patients. The study found that males with two or more allergic diseases had significantly lower levels of vitamin D, while the levels of IgE were negatively correlated with vitamin D in females. Additionally, serum IgE was significantly correlated with children's adaptive skills, and different sexes were associated with different aspects of adaptive skills. Therefore, vitamin D has a protective role in the development of one allergic disease against the coexistence of allergic diseases in males, and the study extends the evidence for sex differences in immunity.
FOOD SCIENCE & NUTRITION
(2023)
Article
Pediatrics
Sheng-Yu Lee, Sung-Chou Li, Chia-Yu Yang, Ho-Chang Kuo, Wen-Jiun Chou, Liang-Jen Wang
Summary: This study investigated the role of gut leakage biomarkers in the susceptibility of ADHD. The results showed that DEFA1 levels were significantly lower in ADHD group compared to the healthy control group. There was no significant difference in serum levels of zonulin and occludin. DEFA1 levels were negatively correlated with inattention scores, while occludin levels were positively correlated with detectability subtest scores. This study provides new insights into the relationship between gut leakage markers and cognition, advancing research on the pathophysiology of ADHD.
Article
Neurosciences
Pei-Chien Chou, Yu Lee, Yung-Yee Chang, Pao-Yen Lin, Liang-Jen Wang
Summary: This study investigated the prevalence, incidence, remission rate, and factors associated with remission of tardive syndrome (TS) in patients using antipsychotics. The findings suggest that TS may be a treatable condition, and early detection and prompt intervention, including closely monitoring antipsychotics-related TS symptoms and using antioxidants, are key to achieving better outcomes.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
(2023)
Article
Clinical Neurology
Yu Lee, Pao-Yen Lin, Nien-Mu Chiu, Chi-Fa Hung, Liang-Jen Wang
Summary: Depressive disorder has a significant impact on patients' daily activities and quality of life, as well as on caregivers who may experience psychological distress. This study aimed to evaluate the prevalence and associated factors of depression in caregivers of patients with depressive disorder. The results showed that depression was the most common psychiatric diagnosis among caregivers, highlighting the importance of early psychiatric diagnosis and appropriate support for improving caregivers' quality of life.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2023)
Review
Medicine, General & Internal
Chin-Chan Lee, Chia-Chun Chen, Cheng-Kai Hsu, Yih-Ting Chen, Chun-Yu Chen, Kai-Jie Yang, Ming-Jui Hung, I-Wen Wu
Summary: Diabetic kidney disease is a common primary disease of end-stage kidney disease, but there is currently no sensitive and accurate biomarker to predict it. microRNAs, which are noncoding RNAs, have been reported to play a potential role in the pathophysiology of diabetic kidney disease. Urinary microRNAs have emerged as a novel, non-invasive liquid biopsy for disease diagnosis. This review discusses the experimental and clinical evidence of urinary microRNA in the context of diabetic kidney disease and explores its future application in routine practice.
MEDICINA-LITHUANIA
(2023)
Article
Health Care Sciences & Services
Yu Lee, Yung-Yee Chang, Ying-Fa Chen, Tsu-Kung Lin, Chi-Fa Hung, Yu-Jie Chiou, Liang-Jen Wang
Summary: This study aimed to compare the prevalence and risk factors of depression between patients with Parkinson's disease (PD) and their caregivers. The findings showed that depressive disorders were common in both PD patients and their caregivers, and were associated with factors such as fatigue, suicide risk, pain, and anxiety. These findings provide references for early detection and treatment of depressive disorders in PD patients and their caregivers.
Article
Pharmacology & Pharmacy
Sheng-Yu Lee, Liang-Jen Wang, Yao-Hsu Yang, Chih-Wei Hsu
Summary: This study compared the effectiveness of different antidepressants in treating youths with major depressive disorder (MDD). The findings suggest that bupropion may be more effective than fluoxetine in preventing hospitalization and maintaining drug therapy, while mirtazapine users have a higher risk of hospitalization.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
(2022)