Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering
Authors
Keywords
-
Journal
Molecular BioSystems
Volume 11, Issue 1, Pages 38-59
Publisher
Royal Society of Chemistry (RSC)
Online
2014-10-20
DOI
10.1039/c4mb00443d
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Production of triacylglycerols in Escherichia coli by deletion of the diacylglycerol kinase gene and heterologous overexpression of atfA from Acinetobacter baylyi ADP1
- (2014) Helge Jans Janßen et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- The chain-flipping mechanism of ACP (acyl carrier protein)-dependent enzymes appears universal
- (2014) John E. Cronan BIOCHEMICAL JOURNAL
- Systems metabolic engineering design: Fatty acid production as an emerging case study
- (2014) Ting Wei Tee et al. BIOTECHNOLOGY AND BIOENGINEERING
- Versatility of Acyl-Acyl Carrier Protein Synthetases
- (2014) Joris Beld et al. CHEMISTRY & BIOLOGY
- Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems
- (2014) Martin Grininger CURRENT OPINION IN STRUCTURAL BIOLOGY
- The initiation ketosynthase (FabH) is the sole rate-limiting enzyme of the fatty acid synthase of Synechococcus sp. PCC 7002
- (2014) James Kuo et al. METABOLIC ENGINEERING
- Chemoenzymatic exchange of phosphopantetheine on protein and peptide
- (2014) Nicolas M. Kosa et al. Chemical Science
- Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa
- (2013) Cyprian D. Cukier et al. ACS Chemical Biology
- Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of MCAT fromSynechocystissp. PCC 6803
- (2013) Yinghui Liu et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Ketoacyl synthase domain is a major determinant for fatty acyl chain length in Saccharomyces cerevisiae
- (2013) Juthaporn Sangwallek et al. ARCHIVES OF MICROBIOLOGY
- Metabolic Flux between Unsaturated and Saturated Fatty Acids Is Controlled by the FabA:FabB Ratio in the Fully Reconstituted Fatty Acid Biosynthetic Pathway of Escherichia coli
- (2013) Xirui Xiao et al. BIOCHEMISTRY
- Engineering ofSaccharomyces cerevisiaefor the synthesis of short chain fatty acids
- (2013) Christopher Leber et al. BIOTECHNOLOGY AND BIOENGINEERING
- FabQ, a Dual-Function Dehydratase/Isomerase, Circumvents the Last Step of the Classical Fatty Acid Synthesis Cycle
- (2013) Hongkai Bi et al. CHEMISTRY & BIOLOGY
- Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel
- (2013) Jillian L. Blatti et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Disruption of plastid acyl:acyl carrier protein synthetases increases medium chain fatty acid accumulation in seeds of transgenic Arabidopsis
- (2013) Henrik Tjellström et al. FEBS LETTERS
- Cloning and stress-responding expression analysis of malonyl CoA-acyl carrier protein transacylase gene of Nannochloropsis gaditana
- (2013) Jinhu Tian et al. GENE
- The Green Revolution 2.0: the potential of algae for the production of biofuels and bioproducts
- (2013) Stephen Mayfield GENOME
- Evolution of acyl-ACP thioesterases and β-ketoacyl-ACP synthases revealed by protein–protein interactions
- (2013) Joris Beld et al. JOURNAL OF APPLIED PHYCOLOGY
- Borrowing genes from Chlamydomonas reinhardtii for free fatty acid production in engineered cyanobacteria
- (2013) Anne M. Ruffing JOURNAL OF APPLIED PHYCOLOGY
- Sulfonyl 3-Alkynyl Pantetheinamides as Mechanism-Based Cross-Linkers of Acyl Carrier Protein Dehydratase
- (2013) Fumihiro Ishikawa et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Metabolic engineering of Phaeodactylum tricornutum for the enhanced accumulation of omega-3 long chain polyunsaturated fatty acids
- (2013) Mary L. Hamilton et al. METABOLIC ENGINEERING
- The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life
- (2013) Joris Beld et al. NATURAL PRODUCT REPORTS
- Trapping the dynamic acyl carrier protein in fatty acid biosynthesis
- (2013) Chi Nguyen et al. NATURE
- Improving Fatty Acid Availability for Bio-Hydrocarbon Production in Escherichia coli by Metabolic Engineering
- (2013) Fengming Lin et al. PLoS One
- Tailored fatty acid synthesis via dynamic control of fatty acid elongation
- (2013) J. P. Torella et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cloning and functional analysis of putative malonyl-CoA:acyl-carrier protein transacylase gene from the docosahexaenoic acid-producer Schizochytrium sp. TIO1101
- (2013) Rubin Cheng et al. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
- Enhancement of Long-Chain Fatty Acid Production in Escherichia coli by Coexpressing Genes, Including fabF, Involved in the Elongation Cycle of Fatty Acid Biosynthesis
- (2012) Seunghan Lee et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Metabolic phenotyping of the cyanobacterium Synechocystis 6803 engineered for production of alkanes and free fatty acids
- (2012) Ping Hu et al. APPLIED ENERGY
- Identification of Transport Proteins Involved in Free Fatty Acid Efflux in Escherichia coli
- (2012) R. M. Lennen et al. JOURNAL OF BACTERIOLOGY
- Improved Production of Long-Chain Fatty Acid in Escherichia coli by an Engineering Elongation Cycle During Fatty Acid Synthesis (FAS) Through Genetic Manipulation
- (2012) Eunyoung Jeon JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- Cloning and characterization of a β-ketoacyl-acyl carrier protein synthase II from Jatropha curcas
- (2012) Qian Wei et al. JOURNAL OF PLANT PHYSIOLOGY
- Enhancing fatty acid production by the expression of the regulatory transcription factor FadR
- (2012) Fuzhong Zhang et al. METABOLIC ENGINEERING
- Production of extracellular fatty acid using engineered Escherichia coli
- (2012) Hui Liu et al. Microbial Cell Factories
- Functional characterizations of malonyl-CoA:acyl carrier protein transacylase (MCAT) in Eimeria tenella
- (2012) Mingfei Sun et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- An ACP-Independent Fatty Acid Synthesis Pathway in Archaea: Implications for the Origin of Phospholipids
- (2012) Jonathan Lombard et al. MOLECULAR BIOLOGY AND EVOLUTION
- Deorphanization of Malonyl CoA:ACP Transacylase Drug Target in Plasmodium falciparum (PfFabD) Using Bacterial Antagonists: A ‘Piggyback’ Approach for Antimalarial Drug Discovery
- (2012) M. Asha Latha Sreshty et al. Molecular Informatics
- The structural role of the carrier protein – active controller or passive carrier
- (2012) John Crosby et al. NATURAL PRODUCT REPORTS
- Reversible labeling of native and fusion-protein motifs
- (2012) Nicolas M Kosa et al. NATURE METHODS
- Crosstalk of Escherichia coli FadR with Global Regulators in Expression of Fatty Acid Transport Genes
- (2012) Youjun Feng et al. PLoS One
- Manipulating Fatty Acid Biosynthesis in Microalgae for Biofuel through Protein-Protein Interactions
- (2012) Jillian L. Blatti et al. PLoS One
- Feedback regulation of plastidic acetyl-CoA carboxylase by 18:1-acyl carrier protein in Brassica napus
- (2012) C. Andre et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineering Escherichia coli for Biodiesel Production Utilizing a Bacterial Fatty Acid Methyltransferase
- (2011) Parwez Nawabi et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Engineering of Bacterial Methyl Ketone Synthesis for Biofuels
- (2011) Ee-Been Goh et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Terminal Olefin (1-Alkene) Biosynthesis by a Novel P450 Fatty Acid Decarboxylase fromJeotgalicoccusSpecies
- (2011) Mathew A. Rude et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Renewable energy from Cyanobacteria: energy production optimization by metabolic pathway engineering
- (2011) Naira Quintana et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Improvement of fatty acid biosynthesis by engineered recombinant Escherichia coli
- (2011) Sunhee Lee et al. BIOTECHNOLOGY AND BIOPROCESS ENGINEERING
- Improving fatty acid production in escherichia coli through the overexpression of malonyl coA-Acyl carrier protein transacylase
- (2011) Xiujun Zhang et al. BIOTECHNOLOGY PROGRESS
- Phylogenetic and experimental characterization of an acyl-ACP thioesterase family reveals significant diversity in enzymatic specificity and activity
- (2011) Fuyuan Jing et al. BMC BIOCHEMISTRY
- Plasmodium falciparum Apicoplast Drugs: Targets or Off-Targets?
- (2011) Cyrille Y. Botté et al. CHEMICAL REVIEWS
- Synthesis of the α,ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway
- (2011) John E Cronan et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Is bacterial fatty acid synthesis a valid target for antibacterial drug discovery?
- (2011) Joshua B Parsons et al. CURRENT OPINION IN MICROBIOLOGY
- Development of Escherichia coli MG1655 strains to produce long chain fatty acids by engineering fatty acid synthesis (FAS) metabolism
- (2011) Eunyoung Jeon et al. ENZYME AND MICROBIAL TECHNOLOGY
- Efficient free fatty acid production in Escherichia coli using plant acyl-ACP thioesterases
- (2011) Xiujun Zhang et al. METABOLIC ENGINEERING
- The Vibrio cholerae fatty acid regulatory protein, FadR, represses transcription of plsB, the gene encoding the first enzyme of membrane phospholipid biosynthesis
- (2011) Youjun Feng et al. MOLECULAR MICROBIOLOGY
- Complex binding of the FabR repressor of bacterial unsaturated fatty acid biosynthesis to its cognate promoters
- (2011) Youjun Feng et al. MOLECULAR MICROBIOLOGY
- Crystal structure of malonyl CoA-Acyl carrier protein transacylase from Xanthomanous oryzae pv. oryzae and its proposed binding with ACP
- (2011) Sampath Natarajan et al. MOLECULES AND CELLS
- Should fracking stop?
- (2011) Robert W. Howarth et al. NATURE
- Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0
- (2011) Jan Schellenberger et al. Nature Protocols
- Engineering plastid fatty acid biosynthesis to improve food quality and biofuel production in higher plants
- (2011) Marcelo Rogalski et al. PLANT BIOTECHNOLOGY JOURNAL
- In vitro reconstitution and steady-state analysis of the fatty acid synthase from Escherichia coli
- (2011) X. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fatty acid production in genetically modified cyanobacteria
- (2011) X. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural classification and properties of ketoacyl synthases
- (2011) Yingfei Chen et al. PROTEIN SCIENCE
- Widespread Head-to-Head Hydrocarbon Biosynthesis in Bacteria and Role of OleA
- (2010) D. J. Sukovich et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Increasing unsaturated fatty acid contents in Escherichia coli by coexpression of three different genes
- (2010) Yujin Cao et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Current understanding of fatty acid biosynthesis and the acyl carrier protein
- (2010) David I. Chan et al. BIOCHEMICAL JOURNAL
- A mechanism based protein crosslinker for acyl carrier protein dehydratases
- (2010) Jordan L. Meier et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A process for microbial hydrocarbon synthesis: Overproduction of fatty acids inEscherichia coliand catalytic conversion to alkanes
- (2010) Rebecca M. Lennen et al. BIOTECHNOLOGY AND BIOENGINEERING
- Recognition of Intermediate Functionality by Acyl Carrier Protein over a Complete Cycle of Fatty Acid Biosynthesis
- (2010) Eliza Płoskoń et al. CHEMISTRY & BIOLOGY
- New design platform for malonyl-CoA-acyl carrier protein transacylase
- (2010) Seung Kon Hong et al. FEBS LETTERS
- Overlapping Repressor Binding Sites Result in Additive Regulation of Escherichia coli FadH by FadR and ArcA
- (2010) Y. Feng et al. JOURNAL OF BACTERIOLOGY
- NMR Solution Structure and Biophysical Characterization ofVibrio harveyiAcyl Carrier Protein A75H
- (2010) David I. Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanism of Substrate Shuttling by the Acyl-Carrier Protein within the Fatty Acid Mega-Synthase
- (2010) Claudio Anselmi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Quantitative analysis and engineering of fatty acid biosynthesis in E. coli
- (2010) Tiangang Liu et al. METABOLIC ENGINEERING
- Genetic engineering of fatty acid chain length in Phaeodactylum tricornutum
- (2010) Randor Radakovits et al. METABOLIC ENGINEERING
- Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals
- (2010) Paul Handke et al. METABOLIC ENGINEERING
- Activity-guided engineering of natural product carrier proteins
- (2010) Andrew S. Worthington et al. Molecular BioSystems
- Microbial production of fatty-acid-derived fuels and chemicals from plant biomass
- (2010) Eric J. Steen et al. NATURE
- The chemical toolbox for monitoring protein fatty acylation and prenylation
- (2010) Rami N Hannoush et al. Nature Chemical Biology
- Structural and functional analyses of a saturated acyl ACP thioesterase, type B from immature seed tissue of Jatropha curcas
- (2010) K. G. Srikanta Dani et al. PLANT BIOLOGY
- Metabolic Engineering of Seeds Can Achieve Levels of -7 Fatty Acids Comparable with the Highest Levels Found in Natural Plant Sources
- (2010) H. T. Nguyen et al. PLANT PHYSIOLOGY
- Fatty Acid Activation in Cyanobacteria Mediated by Acyl-Acyl Carrier Protein Synthetase Enables Fatty Acid Recycling
- (2010) D. Kaczmarzyk et al. PLANT PHYSIOLOGY
- Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy
- (2010) P. Gipson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression, purification and characterization of the acyl carrier protein phosphodiesterase from Pseudomonas Aeruginosa
- (2010) Elavazhagan Murugan et al. PROTEIN EXPRESSION AND PURIFICATION
- Thioesterases: A new perspective based on their primary and tertiary structures
- (2010) David C. Cantu et al. PROTEIN SCIENCE
- Structures of domains I and IV from YbbR are representative of a widely distributed protein family
- (2010) Adam W. Barb et al. PROTEIN SCIENCE
- Microbial Biosynthesis of Alkanes
- (2010) A. Schirmer et al. SCIENCE
- Structure and Malonyl CoA-ACP Transacylase Binding ofStreptomyces coelicolorFatty Acid Synthase Acyl Carrier Protein
- (2009) Christopher J. Arthur et al. ACS Chemical Biology
- Expression ofVibrio harveyiAcyl-ACP Synthetase Allows Efficient Entry of Exogenous Fatty Acids into theEscherichia coliFatty Acid and Lipid A Synthetic Pathways
- (2009) Yanfang Jiang et al. BIOCHEMISTRY
- Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis
- (2009) Lei Zhu et al. BMC MICROBIOLOGY
- Diversity in enoyl-acyl carrier protein reductases
- (2009) R. P. Massengo-Tiassé et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A New Member of the Escherichia coli fad Regulon: Transcriptional Regulation of fadM (ybaW)
- (2009) Y. Feng et al. JOURNAL OF BACTERIOLOGY
- Acyl-Acyl Carrier Protein Regulates Transcription of Fatty Acid Biosynthetic Genes via the FabT Repressor inStreptococcus pneumoniae
- (2009) Agoston Jerga et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Escherichia coli Unsaturated Fatty Acid Synthesis
- (2009) Youjun Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering
- (2009) Wenjuan Zha et al. METABOLIC ENGINEERING
- An alternative to fish oils: Metabolic engineering of oil-seed crops to produce omega-3 long chain polyunsaturated fatty acids
- (2009) Mónica Venegas-Calerón et al. PROGRESS IN LIPID RESEARCH
- Multimeric Options for the Auto-Activation of the Saccharomyces cerevisiae FAS Type I Megasynthase
- (2009) Patrik Johansson et al. STRUCTURE
- The Lactococcus lactis FabF fatty acid synthetic enzyme can functionally replace both the FabB and FabF proteins of Escherichia coli and the FabH protein of Lactococcus lactis
- (2008) Rachael M. Morgan-Kiss et al. ARCHIVES OF MICROBIOLOGY
- Plasmid selection in Escherichia coli using an endogenous essential gene marker
- (2008) Shan Goh et al. BMC BIOTECHNOLOGY
- Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the β-ketoacyl reductase reaction
- (2008) María Jesús Vázquez et al. FEBS Journal
- Bacteria Possessing Two RelA/SpoT-Like Proteins Have Evolved a Specific Stringent Response Involving the Acyl Carrier Protein-SpoT Interaction
- (2008) A. Battesti et al. JOURNAL OF BACTERIOLOGY
- Overproduction of free fatty acids in E. coli: Implications for biodiesel production
- (2008) Xuefeng Lu et al. METABOLIC ENGINEERING
- Cloning and characterization of a gene involved in triacylglycerol biosynthesis and identification of additional homologous genes in the oleaginous bacterium Rhodococcus opacus PD630
- (2008) A. F. Alvarez et al. MICROBIOLOGY-SGM
- Divergent evolution of the thiolase superfamily and chalcone synthase family
- (2008) C JIANG et al. MOLECULAR PHYLOGENETICS AND EVOLUTION
- The Crystal Structure of a Mammalian Fatty Acid Synthase
- (2008) T. Maier et al. SCIENCE
- A substitutive substrate for measurements of β-ketoacyl reductases in two fatty acid synthase systems
- (2007) Ying-Hui Sun et al.
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now