Systems biology-based discovery of a potential Atg4B agonist (Flubendazole) that induces autophagy in breast cancer

In vitro systems for Atg8 lipidation

(2015) Bettina Zens et al.   METHODS

Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer

(2015) Leilei Fu et al.   Oncotarget

A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors

(2014) Debra Akin et al.   Autophagy

ATG4B promotes colorectal cancer growth independent of autophagic flux

(2014) Pei-Feng Liu et al.   Autophagy

The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells

(2014) K. Rothe et al.   BLOOD

Context-dependent role of ATG4B as target for autophagy inhibition in prostate cancer therapy

(2013) Elisa Tran et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

YL529, a novel, orally available multikinase inhibitor, potently inhibits angiogenesis and tumour growth in preclinical models

(2013) Youzhi Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

Network-Based Identification of Novel Connections Among Apoptotic Signaling Pathways in Cancer

(2012) Nan Wang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

A high-throughput FRET-based assay for determination of Atg4 activity

(2012) Min Li et al.   Autophagy

JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-induced autophagy in MCF-7 cells

(2012) Yanchun Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

BioGRID REST Service, BiogridPlugin2 and BioGRID WebGraph: new tools for access to interaction data at BioGRID

(2011) Andrew G. Winter et al.   BIOINFORMATICS

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Kinetics Comparisons of Mammalian Atg4 Homologues Indicate Selective Preferences toward Diverse Atg8 Substrates

(2010) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Modeling of Crystalline Alkylthiophene Oligomers and Polymers

(2010) Margherita Moreno et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis

(2009) V. M. S. Betin et al.   JOURNAL OF CELL SCIENCE

DOCK 6: Combining techniques to model RNA-small molecule complexes

(2009) P. T. Lang et al.   RNA

Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy

(2008) A. Apel et al.   CANCER RESEARCH

An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE