Surface Modification of Polyamide 6 Immobilized with Collagen: Characterization and Cytocompatibility

Polyamide 6 (PA6) membranes were exposed to Ar plasma to produce peroxides on their surfaces, followed by grafting polymerization of methacrylic acid (MAA) introducing -COOH on surfaces. PA6 membranes immobilized with collagen I were obtained by coupling collagen to the MAA graft chains. The physicochemical properties were characterized by contact angle measurement, ATR-FTIR, XPS, and AFM. The results showed that the hydrophilicity of the surface improved after surface modification. The surface topography of the original and the modified PA 6 membranes showed an increase in roughness. Moreover, collagen immobilized onto PA 6 membranes showed enhanced growth in ROB culture tests.