Journal
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
Volume 76, Issue 10, Pages 1471-1473Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijporl.2012.06.025
Keywords
Ion-bombarded silicone; Ciprofloxacin-resistant Pseudomonas aeruginosa; Biofilm
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Funding
- National Research Foundation (NRF)
- Korea government (MEST) through the Research Center for Resistant Cells [R13-2003-009]
- Research Fund from Chosun University
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Objectives: Many materials and surface preparations have been developed to resist the formation of biofilm. Ion-bombarded silicone tympanostomy tube was introduced to resist both staphylococcal and pseudomonal biofilm formation. To date, there are no reports that have evaluated the use of ion-bombarded tympanostomy tubes against the ciprofloxacin-resistant Pseudomonas aeruginosa (CRPA) biofilm formation. The purpose of this study is to evaluate the ion-bombarded tympanostomy tube for CRPA biofilm resistance. Methods: Commercial ion-bombarded tympanostomy tubes and simple silicone tympanostomy tubes were processed for an evaluation of the CRPA biofilm formation in vitro. Results: The ion-bombarded tubes showed no resistance to CRPA adhesion and biofilm formation. Thick and dense conglomeration was less formed in the ion-bombarded tympanostomy tubes, compared to that of the simple silicone tube. Conclusion: The preventive effect against the CRPA biofilm formation of the ion-bombarded silicone tympanostomy tube was not observed. Our result suggests that only the surface modification by an ion bombardment is not enough to resist CRPA biofilm formation. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
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