Review
Biochemistry & Molecular Biology
Su Young Jung, Dokyoung Kim, Dong Choon Park, Eun Hye Lee, Yong-Sung Choi, Jeewon Ryu, Sang Hoon Kim, Seung Geun Yeo
Summary: Otitis media is caused by various factors including infections, anatomo-physiological abnormalities, allergies, and environmental influences. This study highlights the immune responses in otitis media patients, focusing on antibodies and transcription factors produced by B cells, as well as the important functions of B cells in immune defense.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Clinical Neurology
Mathieu Berger, Camila Hirotsu, Jose Haba-Rubio, Monica Betta, Giulio Bernardi, Francesca Siclari, Gerard Waeber, Peter Vollenweider, Pedro Marques-Vidal, Raphael Heinzer
Summary: This study investigated predictors of incident and persistent excessive daytime sleepiness over 5 years in a population-based cohort in Switzerland, and found that factors like male sex, depressive symptoms, poor sleep quality, and obstructive sleep apnea were associated with incident excessive daytime sleepiness, while older age, moderate coffee consumption, leg movement during sleep, and hypertension were protective factors. Further interventional studies are needed to understand the impact of treating these risk factors on excessive daytime sleepiness.
JOURNAL OF SLEEP RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Su Young Jung, Dokyoung Kim, Dong Choon Park, Sung Soo Kim, Tong In Oh, Dae Woong Kang, Sang Hoon Kim, Seung Geun Yeo
Summary: Otitis media is mainly caused by upper respiratory tract infection and eustachian tube dysfunction. The expression of Toll-like receptors (TLRs) is closely related to the occurrence, recurrence, chronicization, and complications of otitis media, playing an important role in the early response to external antigens.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Otorhinolaryngology
Sung Kyun Kim, Min-Woo Park, Chanyang Min, Il-Seok Park, Bumjung Park, Soo-Hwan Byun, Hyo Geun Choi, Seok Jin Hong
Summary: Through a study of Korean health insurance data, it was found that patients with chronic rhinosinusitis have a significantly higher risk of developing chronic otitis media, and the incidence of COM in CRS patients is higher across all age groups and genders.
Article
Public, Environmental & Occupational Health
Michael Nieratschker, Markus Haas, Mateo Lucic, Franziska Pichler, Faris F. Brkic, Thomas Parzefall, Dominik Riss, David T. Liu
Summary: This study aimed to identify associations between extreme weather events and the immediate and delayed risks for acute otitis media (AOM)-related emergency department visits (EV). The results showed that prolonged extreme weather conditions, such as temperature, humidity, precipitation, wind speeds, and atmospheric pressure, significantly impacted the risk ratio (RR) for AOM-related EVs. These findings could improve healthcare resource allocation in similar climates and educate patients about the role of environmental factors in AOM.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Hakan Ashina, David W. Dodick, Jason Barber, Nancy R. Temkin, Catherine D. Chong, Jennifer S. Adler, Ken Shubin Stein, Todd J. Schwedt, Geoffrey T. Manley, TRACK TBI Investigators
Summary: The prevalence and risk factors of post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) were investigated in this study. The results showed that acute PTH was reported by 60.4% of mTBI patients at 2 weeks post-injury, and 52.4% of those with acute PTH reported persistent PTH at 3 months post-injury. Risk factors for acute PTH included younger age, female sex, fewer years of formal education, computed tomography-positive scans, alteration of consciousness, psychiatric history, and history of migraine, while risk factors for persistent PTH included female sex, fewer years of formal education, and history of migraine.
MAYO CLINIC PROCEEDINGS
(2023)
Article
Multidisciplinary Sciences
Maria Gabriella Dona, Massimo Giuliani, Francesca Rollo, Maria Fenicia Vescio, Maria Benevolo, Amalie Giglio, Eugenia Giuliani, Aldo Morrone, Alessandra Latini
Summary: HIV-infected men who have sex with men (MSM) have a higher prevalence of anal infection by high-risk HPV and incidence of anal carcinoma. Use of cART reduces the risk of acquiring anal infection by high-risk HPV.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Yasuyuki Kinoshita, Akira Taguchi, Fumiyuki Yamasaki, Atsushi Tominaga, Kazunori Arita, Nobutaka Horie
Summary: This retrospective study examined the natural course of Rathke's cleft cysts (RCCs) and identified the risk factors for their progression. The results showed that 10% of RCCs progressed, 31.9% spontaneously regressed, and the remaining 133 RCCs remained stable. Older age and initially presenting symptom of acute headache were associated with increased risk of RCC progression and spontaneous regression, respectively.
JOURNAL OF NEUROSURGERY
(2023)
Article
Public, Environmental & Occupational Health
Huiqian Yu, Dantong Gu, Fangzhou Yu, Qingzhong Li
Summary: This study evaluates the additional benefits of social distancing in reducing the prevalence of acute otitis media (AOM) in children, especially during the COVID-19 pandemic. The results show that the implementation of social distancing measures in 2020 led to a 63.6% reduction in AOM outpatient attendance, indicating that social distancing, mask usage, and good hand hygiene can significantly decrease the incidence of AOM.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Health Care Sciences & Services
Anni Yang, Menglei Jv, Jun Zhang, Yuqi Hu, Jiaoping Mi, Haiyu Hong
Summary: This study aimed to investigate whether children with AH have a higher prevalence of obesity and to analyze the risk factors for OME in AH children. The results showed that the prevalence of overweight or obesity was higher in children with AH compared to the control group. The size of adenoids, white blood cell count, neutrophil count, monocyte count, and atopic conditions were found to be associated with OME in AH children.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2023)
Article
Virology
Javeria Rafique Rao, Shazia Rafique, Amjad Ali, Gouhar Rehman, Muhammad Ilyas, Muhammad Idrees
Summary: The study evaluated genetic heterogeneity of HCV HVR1 in infected Pakistani population, showing predominance of genotype 3a and significant genetic diversity within each patient. GHOST results suggested potential genetic relatedness between HCV cases in a non-high-risk population, highlighting the importance of countrywide investigation of outbreaks for disease control.
ARCHIVES OF VIROLOGY
(2021)
Article
Multidisciplinary Sciences
Benedict D. D. Chivers, Melissa R. D. Keeler, Charlotte C. C. Burn
Summary: The impacts of ear disease on animal welfare and behaviour in pet rabbits were investigated. It was found that approximately 28.5% of rabbits had experienced ear conditions, with otitis and excess cerumen being the most common. Lop-eared rabbits were more at risk compared to erect-eared rabbits, and older rabbits were also more susceptible. Improved recognition, treatment, and prevention of ear conditions are necessary to improve welfare standards in pet rabbits.
Article
Health Care Sciences & Services
Tzong-Hann Yang, Alison H. Chang, Yen-Fu Cheng, Chin-Shyan Chen, Herng-Ching Lin
Summary: This study investigated the association between Sjogren's syndrome and chronic otitis media using a representative dataset of the Taiwanese population. The findings showed that patients with chronic otitis media were more likely to have Sjogren's syndrome. This finding can guide physicians in counseling patients with Sjogren's syndrome on the possibility of chronic otitis media occurrence.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Shih-Wei Lai, Kuan-Fu Liao, Yu-Hung Kuo, Cheng-Li Lin, Chiu-Shong Liu, Bing-Fang Hwang, Yen-Jen Lai
Summary: The study in Taiwan found that the incidence of herpes zoster was higher during the months of May to October with high ambient temperature and strong ultraviolet radiation. For every 1 degree Celsius increase in ambient temperature per month, the incidence rate of herpes zoster increased by 0.072 per 10,000 persons per month. Similarly, for every 1 MJ m(-2) increase in monthly ultraviolet radiation, the incidence rate of herpes zoster increased by 0.313 per 10,000 persons per month. There is a significant association between ambient temperature, ultraviolet radiation, and the development of herpes zoster.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Otorhinolaryngology
Chase I. Kahn, Rita Wang, Kunal Shetty, Mikayla J. Huestis, Michael B. Cohen, Jessica R. Levi
Summary: The majority of OM videos on Facebook are found to be inadequate for educational purposes. Clinicians should be aware of these videos on OM and the quality of information parents are exposed to.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Review
Health Care Sciences & Services
Kas Woudstra, Rob Reuzel, Maroeska Rovers, Marcia Tummers
Summary: This study provides an overview of participatory approaches in the development of medical devices, categorizing them into collaboration, involvement, and consultation levels. Patients and healthcare professionals are commonly engaged, with workshops and interviews being the most frequently used methods. Challenges include issues related to sampling, analysis, social dynamics, feasibility, and topic scope.
INTERNATIONAL JOURNAL OF HEALTH POLICY AND MANAGEMENT
(2023)
Article
Health Care Sciences & Services
Evelien B. B. van Well, Stan R. W. Wijn, Gerjon Hannink, Janneke P. C. Grutters, Maroeska M. M. Rovers
Summary: Numerous studies have shown that arthroscopic partial meniscectomy (APM) is not (cost-) effective in patients with symptoms attributed to a degenerative meniscus tear. The study found that not performing APM to treat degenerative meniscus tears in the Netherlands can significantly reduce healthcare expenditures by €54 million. Therefore, it is recommended to further reduce the use of APM for this condition.
INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE
(2023)
Article
Medicine, General & Internal
Kasper Daugaard Larsen, Mads Mose Jensen, Anne-Sophie Homoe, Elisabeth Arndal, Grethe Badsberg Samuelsen, Anders Koch, Xiaohui Chen Nielsen, Preben Homoe, Tobias Todsen
Summary: Nasopharyngeal swabs (NPS) are considered the gold standard for SARS-CoV-2 testing, but alternative specimens such as oropharyngeal swabs (OPS) and nasal swabs may be preferable. However, there is still a lack of strong evidence regarding their diagnostic sensitivity for SARS-CoV-2 testing.
Article
Oncology
Carl Frederik Haugaard, Simon Andreasen, Patrick R. G. Eriksen, Caroline Olsen, Katalin Kiss, Kristine Bjorndal, Marie Westergaard-Nielsen, Preben Homoe
Summary: This retrospective cohort study examined the histological tumor types, location, incidence, and survival of benign and malignant salivary gland tumors in the Greenlandic Inuit population. The study found that 76% of the tumors were benign, with pleomorphic adenoma being the most common type. Malignant tumors accounted for 24% of the cases, with lymphoepithelial carcinoma being the most common type. The study provides valuable insights into the epidemiology of salivary gland tumors in the Greenlandic Inuit population.
Article
Otorhinolaryngology
Eva Lykke, Anders Christensen, Karina Juhl, Ulla Feldt-Rasmussen, Mette Friberg Hitz, Sannia Mia Svenningsen Sjostedt, Christoffer Holst Hahn, Ditte Maria Kraik Svensson, Karoline Kanstrup Springborg, Mads Georg Stage, Gitte Bjorn Hvilsom, Linda Maria Hilsted, Morten Dahl, Giedrius Lelkaitis, Andreas Kjaer, Preben Homoe, Christian von Buchwald
Summary: The purpose of this study was to investigate whether near-infrared autofluorescence image guidance can reduce the incidence of hypoparathyroidism in total thyroidectomy. The results showed that near-infrared autofluorescence imaging can improve the detection rate of parathyroid glands and reduce the rate of hypoparathyroidism, but the difference was not statistically significant. Further studies are needed to confirm the use of near-infrared autofluorescence imaging as an auxiliary tool for parathyroid gland identification.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Nursing
Julie Mondahl, Ragnhild Helleso, Thora Grothe Thomsen, Preben Homoe, Elizabeth Emilie Rosted, Kirsten Frederiksen
Summary: Drawing on ethnographic fieldwork, this study aimed to explore how and why inequality in head and neck cancer treatment pathway occurs between patients with low socio-economic status and Danish healthcare. The study identified three concepts that hindered joint action due to different perceptions of interaction between patients and healthcare professionals.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Clinical Neurology
Anna Hojager, Mikkel M. Schoos, Peter K. Tingsgaard, Troels G. Bock, Preben Homoe
Summary: This study investigated the relationship between obstructive sleep apnea (OSA) and cardiovascular disease (CVD) in Danish patients using the risk chart of Systemic Coronary Risk Evaluation (SCORE) from European Society of Cardiology (ESC). The results showed that patients with moderate and severe OSA had an increased 10-year risk of fatal CVD and were undertreated with CVD risk-lowering agents such as statins.
Article
Oncology
Kathryn J. Brayer, Huining Kang, Adel K. El-Naggar, Simon Andreasen, Preben Homoe, Katalin Kiss, Lauge Mikkelsen, Steffen Heegaard, Daniel Pelaez, Acadia Moeyersoms, David T. Tse, Yan Guo, David Y. Lee, Scott A. Ness
Summary: Adenoid cystic carcinoma (ACC) is a distinct tumor that mainly occurs in salivary or lacrimal glands, but can also develop in other tissues. ACC tumors from different organs have remarkably similar gene expression profiles, indicating a dominant ACC phenotype induced by genetic and epigenetic regulatory events. A gene expression biomarker was validated in a new cohort of ACC tumors, correctly identifying 98% of the patients with poor survival, suggesting the need for a clinical test to identify high-risk patients.
Review
Otorhinolaryngology
Ahmed Ehsan Al-Khafaf, Fahd Al-Shahrestani, Yusuf Baysal, Lise Mette Rahbek Gjerdrum, Steffen Heegaard, Lars Moller Pedersen, Preben Homoe
Summary: In this systematic review, the demographics and characteristics of salivary gland lymphomas were presented. The results showed that lymphomas occur in all salivary glands and mainly in elderly female patients, with a close association with Sjogren's syndrome. Depending on the anatomical location, the lymphoma subtypes vary in aggressiveness, stage, and prognosis.
ACTA OTO-LARYNGOLOGICA
(2023)
Article
Infectious Diseases
Denis R. Katundu, Desderius Chussi, Christa E. van der Gaast-de Jongh, Maroeska M. Rovers, Marien I. de Jonge, Gerjon Hannink, Niels van Heerbeek
Summary: Despite the lack of effectiveness, prophylactic antibiotics are still frequently used in children after tonsillectomy. This study investigated the effect of prophylactic amoxicillin and found no significant difference compared to placebo in terms of tonsillitis.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Clinical Neurology
Ilaria Viozzi, Maroeska M. Rovers, Christiaan G. Overduin, Mark ter Laan
Summary: Introduction: The application of stereotactic laser ablation (SLA) for intra-cranial tumours has been growing, but comparative trials are lacking. This study investigated the familiarity with SLA and opinion on potential indications of European neurosurgeons. Results showed that most respondents considered SLA as a treatment option for recurrent glioblastoma, recurrent metastases, and newly diagnosed deep-seated glioblastoma.
Article
Public, Environmental & Occupational Health
A. S. Homoe, N. Thorup, C. V. L. Larsen, P. Homoe
Summary: The frequency of self-reported middle ear and hearing complaints and vertigo/dizziness in adult Greenlanders was estimated. It was found that there has been a decrease in the frequency of these complaints within a 20-year period. In 1995, the youngest age groups had the highest relative number of ear discharge, while in 2014, the percentage decreased significantly. The oldest age group indicated the lowest relative number of experiences of ear discharge in both 1995 and 2014.
INTERNATIONAL JOURNAL OF CIRCUMPOLAR HEALTH
(2023)
Article
Oncology
Ilaria Viozzi, Christiaan G. Overduin, Anne Rijpma, Maroeska M. Rovers, Mark ter Laan
Summary: This study aimed to investigate the effectiveness of laser interstitial thermal therapy (LITT) in the treatment of newly diagnosed glioblastoma (nGBM) that cannot be surgically removed. The findings suggest that conducting a randomized controlled trial (RCT) on LITT in patients with irresectable nGBM is feasible, and initial safety data is acceptable.
JOURNAL OF NEURO-ONCOLOGY
(2023)
Article
Surgery
Bjarki D. Djurhuus, Pedro F. Viana, Esben Ahrens, Sofie S. Nielsen, Harishchandra L. Srinivasan, Mark P. Richardson, Preben Homoe, Harutomo Hasegawa, Ali A. Zarei, Pia L. K. Gauger, Jonas Duun-Henriksen
Summary: This study describes the experience of surgeons in performing subcutaneous electroencephalography implantation procedures. The surgery is generally considered easy to perform and well tolerated by patients. However, some patients may experience headache or pain around the implant for up to 21 days post-operatively.
FRONTIERS IN SURGERY
(2023)
Article
Engineering, Biomedical
Thomas R. F. van Steenbergen, Han Nijsink, Thomas G. E. Eggen, Dennis Janssen, Maroeska M. Rovers, Ingrid C. M. van der Geest, J. J. Futterer
Summary: In this exploratory study on 20 cadaveric bone tumor models, navigated curettage was not found to be more accurate than freehand curettage. However, the presence of remaining tumor indicates that there is still room for improvement in curettage procedures. The novice user was less accurate with navigation compared to freehand, which could be attributed to the learning curve. Furthermore, the expert user employed a different surgical approach, focusing more on complete tumor removal rather than preserving the surrounding bone.
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2023)
Article
Otorhinolaryngology
Adrian Williamson, Erica H. Mcardle, Hussein Jaffal
Summary: This study aims to describe the findings on drug-induced sleep endoscopy (DISE) in infants with laryngomalacia (LM). The results showed that DISE can identify obstruction at the level of the tongue base and complement the assessment of LM severity.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Tanya Chen, Melissa Lee, Evelyn Constantin, Joshua Gurberg, Lily HP. Nguyen
Summary: In the last two decades, there has been a high prevalence of funding and potential conflicts of interest in HSAT publications. Higher quality studies have increased in the last five years, but there still exists a lack of disclosure regarding funding or COI. There is a positive correlation between level of evidence and industry funding.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Stephen I. Pelton, Saskia Hullegie, Amanda J. Leach, Paola Marchisio, Tal Marom, Vishakha Sabharwal, Nader Shaikh, Paula A. Tahtinen, Roderick P. Venekamp
Summary: This study aims to identify and synthesize key research advances in the preventative measures and medical and surgical treatment of uncomplicated otitis media (OM), as well as the impact of the COVID-19 pandemic on OM management. The study found that there have been important advances in OM management in recent years, such as the effectiveness of video discharge instructions in reducing symptoms for parents of children with acute otitis media (AOM) and the efficacy of levofloxacin solution for treating chronic suppurative otitis media.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Thomas L. Haupt, Earl H. Harley
Summary: This study analyzed head and neck injuries caused by BB guns among children under 18 treated in US emergency departments between 1993 and 2019. It found that younger children are at increased risk of hospital admission, and injuries to the eye and neck are strong predictors of hospitalization.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Guy Faibish, Daniel Kaplan, Ariela Knaanie, Sabri Elsaeid, Oren Ziv
Summary: This study compared postoperative complication rates in pediatric cochlear implant candidates with and without otitis media with effusion (OME), and found that ventilation tube insertion for OME increased the rates of acute mastoiditis and chronic suppurative otitis media without cholesteatoma (CSOMWC).
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Andrew T. Gabrielson, Julie Wei
Summary: A survey conducted among members of the American Society of Pediatric Otolaryngology (ASPO) found that pediatric otolaryngologists commonly experience work-related musculoskeletal pain and lack knowledge about surgical ergonomics.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Review
Otorhinolaryngology
Alisha R. Pershad, Emily C. Knox, Rahul K. Shah, Habib G. Zalzal
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Keerthana Rajanbabu, Sakthilakshmi Gunasekaran, Heramba Ganapathy Selvarajan
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Austin D. Schafer, Megan Mcnutt, Amy Fulmer, Tran Bourgeois, Charles A. Elmaraghy
Summary: This study compared the risk of recurrent epistaxis in children treated with silver nitrate or electrocautery. The findings showed that patients treated with silver nitrate had significantly higher risk of recurrence compared to those treated with electrocautery.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
