The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells
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Title
The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells
Authors
Keywords
27-Hydroxycholesterol, Breast cancer, Proliferation, Estrogen, Cholesterol
Journal
MOLECULAR AND CELLULAR BIOCHEMISTRY
Volume 410, Issue 1-2, Pages 187-195
Publisher
Springer Nature
Online
2015-09-08
DOI
10.1007/s11010-015-2551-7
References
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Related references
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- (2015) A. V. Lee et al. JNCI-Journal of the National Cancer Institute
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- (2013) Shira Peleg Hasson et al. Breast Care
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- (2013) E. R. Nelson et al. SCIENCE
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- (2013) Qian Wu et al. Cell Reports
- Nutlin-3, a small-molecule MDM2 inhibitor, sensitizes Caki cells to TRAIL-induced apoptosis through p53-mediated PUMA upregulation and ROS-mediated DR5 upregulation
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- The rebel angel: mutant p53 as the driving oncogene in breast cancer
- (2012) D. Walerych et al. CARCINOGENESIS
- Statin Prescriptions and Breast Cancer Recurrence Risk: A Danish Nationwide Prospective Cohort Study
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- (2011) Michihisa Umetani et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor
- (2010) J. J. Manfredi GENES & DEVELOPMENT
- The C terminus of p53 binds the N-terminal domain of MDM2
- (2010) Masha V Poyurovsky et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mutant p53 mediates survival of breast cancer cells
- (2009) L Y Lim et al. BRITISH JOURNAL OF CANCER
- Modes of p53 Regulation
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- Restoration of p53 Pathway by Nutlin-3 Induces Cell Cycle Arrest and Apoptosis in Human Rhabdomyosarcoma Cells
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- (2007) Carolyn D. DuSell et al. MOLECULAR ENDOCRINOLOGY
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