Fluorofenidone protects against renal fibrosis by inhibiting STAT3 tyrosine phosphorylation

Fluorofenidone Attenuates Inflammation by Inhibiting the NF-κB Pathway

(2014) Ling Huang et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Active Components with Inhibitory Activities on IFN-γ/STAT1 and IL-6/STAT3 Signaling Pathways from Caulis Trachelospermi

(2014) Xiao-Ting Liu et al.   MOLECULES

Fluorofenidone attenuates hepatic fibrosis by suppressing the proliferation and activation of hepatic stellate cells

(2013) Yu Peng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Protective role of JAK/STAT signaling against renal fibrosis in mice with unilateral ureteral obstruction

(2013) Kiyomi Koike et al.   CLINICAL IMMUNOLOGY

The antihepatic fibrotic effects of fluorofenidone via MAPK signalling pathways

(2013) Yu Peng et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Fluorofenidone Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice Via Restoring Caveolin 1 Expression and Inhibiting Mitogen-Activated Protein Kinase Signaling Pathway

(2012) Jie Meng et al.   SHOCK

Fluorofenidone Attenuates Tubulointerstitial Fibrosis by Inhibiting TGF-β1-Induced Fibroblast Activation

(2011) Qiongjing Yuan et al.   AMERICAN JOURNAL OF NEPHROLOGY

Fluorofenidone inhibits Ang II-induced apoptosis of renal tubular cells through blockage of the Fas/FasL pathway

(2011) Wang-bin Ning et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice

(2011) Ling Hao Wang et al.   PHARMACOLOGY

Fluorofenidone protects mice from lethal endotoxemia through the inhibition of TNF-α and IL-1β release

(2010) Yiting Tang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Suppressors of Cytokine Signaling Abrogate Diabetic Nephropathy

(2010) G. Ortiz-Munoz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

(2010) Maoyin Pang et al.   KIDNEY INTERNATIONAL

Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy

(2009) Ting-Chi Lu et al.   KIDNEY INTERNATIONAL

STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria

(2009) Lobelia Samavati et al.   MOLECULAR IMMUNOLOGY

Fluorofenidone attenuates collagen I and transforming growth factor-β1 expression through a nicotinamide adenine dinucleotide phosphate oxidase-dependent way in NRK-52E cells

(2009) ZHANG-ZHE PENG et al.   NEPHROLOGY

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Cytokine Profiling and Stat3 Phosphorylation in Epithelial–Mesenchymal Interactions between Keloid Keratinocytes and Fibroblasts

(2008) Cheh P. Lim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE

The Aggravating Mechanisms of Aldosterone on Kidney Fibrosis

(2008) G. Remuzzi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IL-6/IL-6R Axis Plays a Critical Role in Acute Kidney Injury

(2008) Y. Nechemia-Arbely et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aldosterone Activates NF- B in the Collecting Duct

(2008) V. Leroy et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

STAT3: An Important Regulator of Multiple Cytokine Functions

(2008) Stanislaw M. Stepkowski et al.   TRANSPLANTATION

Anti-inflammatory Renoprotective Effect of Clopidogrel and Irbesartan in Chronic Renal Injury

(2007) X. Tu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY