Article
Oncology
Donatella Arpa, Elisabetta Parisi, Giulia Ghigi, Annalisa Cortesi, Pasquale Longobardi, Patrizia Cenni, Martina Pieri, Luca Tontini, Elisa Neri, Simona Micheletti, Francesca Ghetti, Manuela Monti, Flavia Foca, Anna Tesei, Chiara Arienti, Anna Sarnelli, Giovanni Martinelli, Antonio Romeo
Summary: The study suggests that HSRT delivered after HBO is effective for treating recurrent HGG with low toxicity. This approach could be an alternative for patients who cannot or refuse to undergo systemic therapies.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Grete K. Velure, Bernd Muller, May Aa Hauken
Summary: The purpose of this study was to explore the development and association between symptoms of Late Radiation Tissue Injuries (LRTIs) and health related quality of life (HRQoL) following hyperbaric oxygen therapy. The results showed significant improvements in both LRTIs and HRQoL after the therapy, especially in symptom severity reduction and improvements in social and role functions. This suggests that cancer survivors with LRTIs and impaired HRQoL may benefit from undergoing hyperbaric oxygen therapy.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Medicine, General & Internal
Jacek Siewiera, Michal Smolenski, Natalia Jermakow, Jacek Kot, Klaudia Brodaczewska, Jacek Turyn, Magdalena A. Zabielska-Kaczorowska, Nils Ludwig, Miroslaw J. Szczepanski
Summary: While differences were observed in ADMA, arginine derivatives, and cytokine concentrations among patient groups, HBOT did not have any significant effect on these parameters, suggesting its neutral impact on inflammation and endothelial injury.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Silke D. De Wolde, Rick H. Hulskes, Robert P. Weenink, Markus W. Hollmann, Robert A. Van Hulst
Summary: HBOT has potential new treatment applications in preconditioning for surgery, reducing complications rates and hospital stay by reducing inflammation and promoting angiogenesis through oxidative stress modulation. Further research is needed to determine the implications of these findings for clinical practice.
Article
Oncology
Soumyajit Roy, Scott Grimes, Scott Carlyle Morgan, Libni Eapen, Julia Malone, Julia Craig, Daniel Eidelberg Spratt, Shawn Malone
Summary: Two different sequencing strategies of androgen deprivation therapy (ADT) and radiation therapy in prostate cancer (PCa) were investigated for their impact on health-related quality of life (HR-QoL) in this study. The results showed no significant differences in urinary and bowel symptoms between adjuvant and neoadjuvant approaches, but the adjuvant approach was associated with a reduced risk of deterioration in sexual function.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2021)
Article
Oncology
Antonio Moreira Monteiro, Diogo Alpuim Costa, Virginia Mareco, Carla Espiney Amaro
Summary: This study evaluated the effectiveness and safety of hyperbaric oxygen therapy (HBOT) for radiation-induced proctitis (RIP). The results showed that HBOT had a significant therapeutic effect on RIP, relieving symptoms and improving patients' quality of life.
FRONTIERS IN ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Corine A. Lansdorp, Krisztina B. Gecse, Christianne J. Buskens, Mark Lowenberg, Jaap Stoker, Willem A. Bemelman, Geert R. A. M. D'Haens, Rob A. van Hulst
Summary: This study revealed significant clinical, radiological, and biochemical improvements in Crohn's disease patients with therapy-refractory perianal fistulas after treatment with hyperbaric oxygen.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Emergency Medicine
Sangsoo Han, Sangun Nah, Sungwoo Choi, Gi Woon Kim, Young Hwan Lee
Summary: This study compared the development of DNS in patients with acute CO poisoning after 3 and >3 sessions of HBO therapy. The >3 HBO group had a higher incidence of DNS development compared to the 3 HBO group, but the difference disappeared after propensity score-matching analysis.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Rada Jeremic, Sanja Pekovic, Irena Lavrnja, Ivana Bjelobaba, Marina Djelic, Sanja Dacic, Predrag Brkic
Summary: A growing body of evidence suggests that hyperbaric oxygenation (HBO) can affect the activity of adult neural stem cells (NSCs). In this study, the effects of sensorimotor cortex ablation (SCA) and HBO treatment (HBOT) on neurogenesis in the adult dentate gyrus (DG) were investigated. The results showed that SCA caused significant loss of neurons in the DG, while HBOT prevented the reduction of dendritic arborization and increased proliferation of progenitor cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Correction
Oncology
Marina Kimie Oba, Lara Maria Alencar Ramos Innocentini, Gustavo Viani, Hilton Marcos Alves Ricz, Thiago de Carvalho Reis, Tatiane Cristina Ferrari, Leandro Dorigan de Macedo
Summary: The data in the results section and table 1 is incorrect.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Medicine, General & Internal
Morten Hedetoft, Peter Ostrup Jensen, Claus Moser, Julie Vinkel, Ole Hyldegaard
Summary: The study found that HBO2 treatment was associated with increased levels of MPO and SOD in patients with NSTI, and oxidative stress was more pronounced in patients with septic shock.
JOURNAL OF INVESTIGATIVE MEDICINE
(2021)
Review
Oncology
Diogo Alpuim Costa, J. Guilherme Goncalves-Nobre, Mafalda Sampaio-Alves, Nuno Guerra, Joana Arana Ribeiro, Carla Espiney Amaro
Summary: Neuroblastoma is a common cancer in infants with diverse clinical presentations and prognostic factors. Multimodal therapy approaches include chemotherapy, radiotherapy, immunotherapy, and surgical resection. Hyperbaric oxygen therapy is used as a complementary measure to overcome tumor hypoxia.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Paul Windisch, Jorg-Christian Tonn, Christoph Fuerweger, Felix Ehret, Berndt Wowra, Markus Kufeld, Christian Schichor, Alexander Muacevic
Summary: This study examined changes in quality of life (QoL) and hearing function in patients receiving stereotactic radiation for vestibular schwannomas. The results suggest that preserving proper hearing in the unaffected ear may help maintain a good QoL for patients. Further studies are needed to confirm this association.
Article
Critical Care Medicine
Hussein D. Kanji, Alexandra Chouldechova, Samantha Harris-Fox, Juan J. Ronco, Ephraim O'dea, Chris Harvey, Constantin Shuster, Sonny Thiara, Giles J. Peek
Summary: The study investigated the quality of life outcomes of ARDS patients treated with ECMO at 6 months. The majority of patients had near-normal pulmonary function and good quality of life, but a considerable proportion experienced anxiety, depression, and PTSD symptoms. A significant number of patients faced challenges in returning to usual activities, experiencing pain, and returning to work.
JOURNAL OF CRITICAL CARE
(2021)
Article
Oncology
Ben M. Eyck, J. Jan B. van Lanschot, Maarten C. C. M. Hulshof, Berend J. van der Wilk, Joel Shapiro, Pieter van Hagen, Mark I. van Berge Henegouwen, Bas P. L. Wijnhoven, Hanneke W. M. van Laarhoven, Grard A. P. Nieuwenhuijzen, Geke A. P. Hospers, Johannes J. Bonenkamp, Miguel A. Cuesta, Reinoud J. B. Blaisse, Olivier R. Busch, Geert-Jan M. Creemers, Cornelis J. A. Punt, John Th M. Plukker, Henk M. W. Verheul, Ernst J. Spillenaar Bilgen, Maurice J. C. van der Sangen, Tom Rozema, Fiebo J. W. Ten Kate, Jannet C. Beukema, Anna H. M. Piet, Caroline M. van Rij, Janny G. Reinders, Hugo W. Tilanus, Ewout W. Steyerberg, Ate van der Gaast
Summary: The preoperative chemoradiotherapy regimen according to CROSS study has shown to have a long-term overall survival benefit for patients with locally advanced resectable esophageal or junctional cancer, with a stable effect observed up to 10 years of follow-up.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Education, Special
Kristine M. Jensen de Lopez, Julie Feilberg, Sofia Baena, Rena Lyons, Sam Harding, Maja Kelic, Inge S. Klatte, Tina C. Mantel, Rama Novogrodsky, Thora S. Ulfsdottir, Krisztina Zajdo, Isabel R. Rodriguez-Ortiz
Summary: Researchers conducted cross-cultural qualitative interviews with parents from nine countries who had children with speech-language disorders, finding that parents believe their children's hidden disabilities lead to social exclusion, and they play crucial roles as advocates in social environments.
RESEARCH IN DEVELOPMENTAL DISABILITIES
(2021)
Letter
Radiology, Nuclear Medicine & Medical Imaging
L. I. Jones, S. Taylor-Phillips, R. Geach, S. A. Harding, A. Marshall, S. McKeown-Keegan, J. A. Dunn
CLINICAL RADIOLOGY
(2022)
Article
Oncology
Joanne M. Patterson, Liya Lu, Laura-Jayne Watson, Sam Harding, Andy R. Ness, Steve Thomas, Andrea Waylen, Miranda Pring, Tim Waterboer, Linda Sharp
Summary: The study found significant associations between markers of social functioning and depression and health-related quality of life among head and neck cancer survivors. Difficulty with social eating and contact was positively correlated with depression and negatively correlated with quality of life. Effective interventions addressing social eating and contact are crucial for improving outcomes for survivors.
Review
Audiology & Speech-Language Pathology
Hannah Lane, Sam Harding, Yvonne Wren
Summary: The review suggests that early naturalistic interventions can have positive impacts on the speech development of children with cleft palate with or without cleft lip. However, the overall methodological quality of the publications is weak, and there is a lack of clarity and specificity in terms of therapy technique, delivery, and optimal age of delivery in the current evidence. Future research should use more robust methodological designs to determine the effectiveness of early speech interventions for children born with cleft palate with or without cleft lip.
INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS
(2022)
Article
Audiology & Speech-Language Pathology
Anna Prince, Jonathan Marsden, Yvonne Wren, Rosemarie Hayhow, Sam Harding
Summary: A feasibility study was conducted on The Fluency Trust Residential Course (FTRC) for adolescents who stutter. The results showed that recruitment, retention, and outcome measure completion rates were all 100%. The intervention fidelity was 95% and there were no adverse events. The outcome measures demonstrated good test re-test reliability and the acceptability of the intervention by adolescents was high. The conclusion suggests that a future definitive trial of the FTRC is indicated after additional development work and feasibility testing.
JOURNAL OF COMMUNICATION DISORDERS
(2022)
Review
Education & Educational Research
Caitlin Holme, Sam Harding, Sue Roulstone, Patricia J. Lucas, Yvonne Wren
Summary: This scoping review explores the significance of linguistic interactions between parents and children, as well as the influence of different activity contexts on language use. Results indicate the importance of interaction strategies in children's language development, but future research should focus on ensuring the ecological validity of findings.
INTERNATIONAL JOURNAL OF EARLY YEARS EDUCATION
(2022)
Review
Clinical Neurology
Jonathan Blackman, Hamish Duncan Morrison, Katherine Lloyd, Amy Gimson, Luke Vikram Banerjee, Sebastian Green, Rebecca Cousins, Sarah Rudd, Sam Harding, Elizabeth Coulthard
Summary: This scoping review aims to determine how sleep is currently measured and reported in patients with Mild Cognitive Impairment (MCI) and early dementia. The study found that despite technological advances, questionnaires were still the most commonly used method to measure sleep, and sleep outcome parameters were reported heterogeneously.
Review
Audiology & Speech-Language Pathology
Lucy Rodgers, Sam Harding, Rachel Rees, Michael T. Clarke
Summary: This paper provides an overview of interventions for pre-school children with co-occurring phonological SSD and expressive language difficulties. The review identified both integrated interventions and single-domain interventions, with early evidence supporting their effectiveness. However, further high-quality research is needed to enhance the understanding of interventions for this dual profile.
INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS
(2022)
Review
Medicine, General & Internal
Sam Harding, Sam Burr, Joanne Cleland, Helen Stringer, Yvonne Wren
Summary: This paper presents a protocol for an umbrella review focusing on assessments, interventions and outcomes related to speech sound disorder (SSD) in children. The aim is to identify the most effective care pathways for children with SSD. The protocol includes a detailed search strategy and extraction tool development, following the guidelines of the Joanna Briggs Institute scoping review methods.
Review
Medicine, General & Internal
Kati Hayes, Sam Harding, Kirsten Buckley, Bronagh Blackwood, Jos M. Latour
Summary: This scoping review aimed to explore and map the experiences of family members of adult patients with severe traumatic brain injury (TBI) in the ICU. The thematic analysis revealed three themes: communication with the clinical team, uncertainty, and involvement in care. These findings provide clinicians with a deeper understanding and direction for targeted interventions to support family members in the ICU.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, Research & Experimental
Mary Alvarez, Emily J. Hotton, Sam Harding, Jonathan Ives, Joanna F. Crofts, Julia Wade
Summary: This study highlights the complexity of recruitment to intrapartum research and the challenges women face in understanding and making decisions during urgent interventions. The time pressures of intrapartum interventions make recruitment discussions difficult, yet little is known about these interactions. The study proposes a framework for good practice in information provision to address the concerns of women and midwives and ensure fair inclusion in intrapartum trials.
PILOT AND FEASIBILITY STUDIES
(2023)
Review
Nursing
Claire Lanfear, Sam Harding
Summary: This study aimed to determine the impact of nurse-led follow-up care on the self-management of people with cancer. The systematic review found limited evidence of the effectiveness of nurse-led interventions in improving quality of life, self-efficacy, and distress for cancer patients.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Oncology
Linda Sharp, Laura-Jayne Watson, Liya Lu, Sam Harding, Katrina Hurley, Steve J. Thomas, Joanne M. Patterson
Summary: This study investigated cancer-related fatigue (CRF) in head and neck cancer patients using data from the Head and Neck 5000 prospective clinical cohort. The findings revealed a high prevalence of CRF, indicating the need for additional interventions and supports for affected patients.
Letter
Surgery
Shona McIntosh, Sam Harding, Patrick A. Coughlin, Christopher P. Twine
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Article
Oncology
Lyn Jones, Andrea Marshall, Premkumar Elangovan, Rebecca Geach, Sadie McKeown-Keegan, Sarah Vinnicombe, Sam A. Harding, Sian Taylor-Phillips, Mark Halling-Brown, Christopher Foy, Elizabeth O'Flynn, Hesam Ghiasvand, Claire Hulme, Janet A. Dunn
Summary: The study aimed to examine the diagnostic accuracy of mammogram readers to interpret abbreviated breast MRI (abMRI) after a single day of training and compare the performance between experienced and inexperienced readers of full-protocol breast MRI (fpMRI). The results showed that inexperienced readers had lower diagnostic accuracy compared to experienced readers, suggesting the need for additional training.
BREAST CANCER RESEARCH
(2022)
