Expression of TWEAK/Fn14 in neuroblastoma: Implications in tumorigenesis

The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models

(2012) Jennifer S. Michaelson et al.   CANCER BIOLOGY & THERAPY

Elevated fibroblast growth factor-inducible 14 expression promotes gastric cancer growth via nuclear factor-κB and is associated with poor patient outcome

(2011) Oh-Hyung Kwon et al.   CANCER LETTERS

Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome

(2011) Mingguo Huang et al.   CARCINOGENESIS

Antibodies to TWEAK Receptor Inhibit Human Tumor Growth through Dual Mechanisms

(2010) P. A. Culp et al.   CLINICAL CANCER RESEARCH

Regulation of matrix metalloproteinase activity in health and disease

(2010) Elin Hadler-Olsen et al.   FEBS Journal

High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset

(2010) H. Caren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF-like weak inducer of apoptosis (TWEAK) induces inflammatory and proliferative effects in human kidney cells

(2009) Hua-Xin Gao et al.   CYTOKINE

Neural stem cells at the crossroads: MMPs may tell the way

(2009) Gaetana A. Tonti et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cyclin D1 and CDK4 Activity Contribute to the Undifferentiated Phenotype in Neuroblastoma

(2008) J. J. Molenaar et al.   CANCER RESEARCH

Tumor Necrosis Factor-related Weak Inducer of Apoptosis Augments Matrix Metalloproteinase 9 (MMP-9) Production in Skeletal Muscle through the Activation of Nuclear Factor-κB-inducing Kinase and p38 Mitogen-activated Protein Kinase

(2008) Hong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of Pro-matrix Metalloproteinase-9/Proteoglycan Heteromer with Gelatin and Collagen

(2008) Nabin Malla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

(2008) Jeffrey A. Winkles   NATURE REVIEWS DRUG DISCOVERY