Article
Neurosciences
Galit Yogev-Seligmann, Tamir Eisenstein, Elissa Ash, Nir Giladi, Haggai Sharon, Shikma Nachman, Noa Bregman, Einat Kodesh, Talma Hendler, Yulia Lerner
Summary: This study explored the effects of aerobic exercise intervention and cardiorespiratory fitness improvement on brain and cognitive functions in older adults with amnestic mild cognitive impairment. The results showed increased brain activity and neural synchronization in the aerobic group, while the control group demonstrated decreased brain activity during memory encoding. Increases in cardiorespiratory fitness were associated with improvements in brain activation and performance on neuropsychological tests.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Review
Psychology, Multidisciplinary
Yuxin Yuan, Xiaofen Li, Wanxu Liu
Summary: Dance activities have a significant positive effect on the cognitive functions and sub-domains of older adults with MCI, improving global cognition, memory, visuospatial function, cognitive flexibility, attention, and balance.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Geriatrics & Gerontology
Ranmalee Eramudugolla, Md Hamidul Huque, Joanne Wood, Kaarin J. Anstey
Summary: The study found that among safe drivers, those with mild cognitive impairment (MCI) and cognitively normal (CN) drivers exhibit similar patterns of errors on the road in terms of type and traffic context. However, unsafe drivers with MCI and CN encountered additional difficulties at intersections, roundabouts, parking, straight driving, and under self-navigation conditions.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Psychology, Clinical
Hillary J. Rouse, Brent J. Small, John A. Schinka, David A. Loewenstein, Ranjan Duara, Huntington Potter
Summary: The study found that older adults with mild behavioral impairment (MBI) performed worse on tasks of executive function, attention, and episodic memory than those without MBI. Additionally, individuals with both MCI and MBI showed significantly poorer performance on episodic memory tasks compared to those with only MCI.
INTERNATIONAL PSYCHOGERIATRICS
(2021)
Article
Geriatrics & Gerontology
Aaron Salinas-Rodriguez, Rosa Palazuelos-Gonzalez, Ana Rivera-Almaraz, Betty Manrique-Espinoza
Summary: The study found significant longitudinal associations between sarcopenia, mild cognitive impairment, and cognitive function among older Mexican adults, with a significant increase in the prevalence of mild cognitive impairment and sarcopenia.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Review
Cell Biology
Qian Liu, Weiguang Ni, Lijia Zhang, Mingzhu Zhao, Xuechun Bai, Sitao Zhang, Yiwen Ding, Huiru Yin, Li Chen
Summary: This review found that mind-body exercise was the most effective in improving depressive symptoms in older adults with MCI compared to conventional controls, and that aerobic, mind-body, and multicomponent exercises had beneficial and comparable effects in reducing depressive states in older adults with MCI. These findings may guide clinical geriatric stakeholders and allied health professionals in providing more scientifically optimal exercise prescriptions for older adults with MCI. More high-quality, long-term clinical trials are needed to explore the longer-term dynamic effects.
AGEING RESEARCH REVIEWS
(2023)
Review
Neurosciences
Hui Li, Wenlong Su, Hui Dang, Kaiyue Han, Haitao Lu, Shouwei Yue, Hao Zhang
Summary: Exercise training has a small beneficial effect on executive function and attention in older adults with MCI. Resistance training shows significant improvements in these cognitive measures, while the effects of aerobic exercise remain inconclusive.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Review
Psychiatry
Liming Yong, Lei Liu, Ting Ding, Gao Yang, Haibing Su, Jibing Wang, Ming Yang, Jindong Chang
Summary: Regular aerobic exercise significantly improves cognitive function in older adults with MCI, as indicated by improvements in MMSE and MoCA scores. However, caution should be exercised when interpreting these findings due to the limitations of the study.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Geriatrics & Gerontology
Fuzhong Li, Peter Harmer, Kathleen Fitzgerald, Kerri Winters-Stone
Summary: This study examined the feasibility, acceptability, and safety of a cognitive-enhancing Tai Ji Quan training intervention delivered remotely via videoconferencing for older adults with mild cognitive impairment (MCI). The results showed that the intervention was feasible, acceptable, and safe, with high retention rates and positive trends in cognitive outcomes. The findings suggest that remote Tai Ji Quan training could be a viable option for older adults with MCI.
Article
Physiology
Danny J. Yu, Angus P. Yu, Joshua D. K. Bernal, Daniel Y. Fong, Derwin K. C. Chan, Calvin P. Cheng, Parco M. Siu
Summary: This study aimed to evaluate the effectiveness of the World Health Organization-recommended minimal volume of aerobic-type physical activity in improving cognitive performance in middle-aged and older adults with mild cognitive impairment (MCI). The results showed that performing 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity walking exercise once or thrice weekly can improve cognitive performance, as well as reduce anxiety severity and improve cardiorespiratory fitness.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Health Care Sciences & Services
Tsuyoshi Katsurasako, Shin Murata, Akio Goda, Kayoko Shiraiwa, Jun Horie, Teppei Abiko, Hideki Nakano
Summary: The combination of MCI and pre-frailty may lead to declines in both physical and psychological functions as well as instrumental activities of daily living (IADL) in older adults.
Article
Neurosciences
Junyeon Won, Daniel D. Callow, Gabriel S. Pena, Leslie S. Jordan, Naomi A. Arnold-Nedimala, Kristy A. Nielson, J. Carson Smith
Summary: The study found that after 12 weeks of exercise training, there was a significant increase in hippocampal functional connectivity in older adults, which may reflect neural network plasticity associated with exercise training-related improvements in memory performance in individuals with mild cognitive impairment.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Psychiatry
Felippe Mendonca, Felipe Kenji Sudo, Gustavo Santiago-Bravo, Natalia Oliveira, Naima Assuncao, Fernanda Rodrigues, Rejane Soares, Victor Calil, Gabriel Bernardes, Pilar Erthal, Claudia Drummond, Fernanda Tovar-Moll, Paulo Mattos
Summary: Older individuals with ADHD and MCI exhibit differences in cognitive and behavioral functions, but share overlapping cognitive profiles. Clinicians should be aware of these overlapping phenotypes to prevent misdiagnosis.
FRONTIERS IN PSYCHIATRY
(2021)
Review
Geriatrics & Gerontology
Juhyun Ahn, Myoungsuk Kim
Summary: We conducted a systematic review and meta-analysis to determine the integrated effect of aerobic exercise on cognitive function and sleep in older adults with mild cognitive impairment (MCI) and to optimize exercise methods for improving cognitive function. Our analysis of 11 studies showed that aerobic exercise training significantly improved global cognitive function in older adults with MCI, but had no significant effect on sleep improvement. Different types of aerobic exercise, exercise time, and exercise frequency had varying effects on cognitive function improvement, with exercise frequency being the most significant factor.
Article
Neurosciences
Tamir Eisenstein, Galit Yogev-Seligmann, Elissa Ash, Nir Giladi, Haggai Sharon, Irit Shapira-Lichter, Shikma Nachman, Talma Hendler, Yulia Lerner
Summary: This study suggests that maximal aerobic capacity (MAC) may be associated with hippocampal-related cognitive reserve in aMCI patients by altering the relationship between hippocampal-related structural deterioration and cognitive function. Additionally, MAC is found to be associated with increased capacity to recruit neural resources during increased cognitive demands.