Icariin, a phoshphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling

Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells

(2013) Matharage Gayani Dilshara et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Nitric Oxide Synthesis and cGMP Production Is Important for Neurite Growth and Synapse Remodeling after Axotomy

(2013) R. M. Cooke et al.   JOURNAL OF NEUROSCIENCE

Phosphodiesterases as Therapeutic Targets for Alzheimer's Disease

(2012) Ana García-Osta et al.   ACS Chemical Neuroscience

Treating Erectile Dysfunction and Central Neurological Diseases with Oral Phosphodiesterase Type 5 Inhibitors. Review of the Literature

(2012) Giuseppe Lombardi et al.   Journal of Sexual Medicine

Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease

(2011) Jun Zhou et al.   BRAIN RESEARCH

APP physiological and pathophysiological functions: insights from animal models

(2011) Qinxi Guo et al.   CELL RESEARCH

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Endothelial Nitric Oxide Modulates Expression and Processing of Amyloid Precursor Protein

(2010) Susan A. Austin et al.   CIRCULATION RESEARCH

Alzheimer Disease

(2010) Rudy J. Castellani et al.   DM DISEASE-A-MONTH

Phoshphodiesterase-5 Inhibitors: Novel Weapons Against Alzheimer's Disease?

(2010) Behnam Sabayan et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

The Genetics of Alzheimer Disease: Back to the Future

(2010) Lars Bertram et al.   NEURON

Icariin isolated from Epimedium brevicornum Maxim attenuates learning and memory deficits induced by d-galactose in rats

(2010) Fei Li et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Protective effects of icariin on brain dysfunction induced by lipopolysaccharide in rats

(2010) J. Guo et al.   PHYTOMEDICINE

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

PROTECTIVE EFFECTS OF ICARIIN ON COGNITIVE DEFICITS INDUCED BY CHRONIC CEREBRAL HYPOPERFUSION IN RATS

(2009) Rui-Xia Xu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Icariin inhibits beta-amyloid peptide segment 25–35 induced expression of β-secretase in rat hippocampus

(2009) Jing Nie et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Phosphodiesterase 5 Inhibition Improves Synaptic Function, Memory, and Amyloid-  Load in an Alzheimer's Disease Mouse Model

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications

(2009) Li Zhou et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Expression of VEGF, iNOS, and eNOS is increased in cochlea of diabetic rat

(2008) Fang Liu et al.   ACTA OTO-LARYNGOLOGICA

Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells

(2008) Byung-Hee Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Amyloid beta toxicity dependent upon endothelial cell state

(2008) Mercedes Balcells et al.   NEUROSCIENCE LETTERS