Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase

(2012) P. B. Martinez de Morentin et al.   DIABETES

Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?

(2012) Silje Skrede et al.   JOURNAL OF LIPID RESEARCH

Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro

(2012) Alberto Canfrán-Duque et al.   JOURNAL OF LIPID RESEARCH

Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism

(2012) Luis Varela et al.   JOURNAL OF PATHOLOGY

Chronic olanzapine administration in rats: Effect of route of administration on weight, food intake and body composition

(2012) Steve Mann et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A Role for Hypothalamic AMP-Activated Protein Kinase in the Mediation of Hyperphagia and Weight Gain Induced by Chronic Treatment with Olanzapine in Female Rats

(2011) Ei Sejima et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats

(2011) Silje Skrede et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Chronic treatment with olanzapine via a novel infusion pump induces adiposity in male rats

(2011) Miwako Shobo et al.   LIFE SCIENCES

Modeling chronic olanzapine exposure using osmotic minipumps: Pharmacological limitations

(2011) Gary Remington et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat

(2011) Goran Jassim et al.   PSYCHOPHARMACOLOGY

Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: Relationship with stearoyl-CoA desaturase activity

(2011) Robert K. McNamara et al.   SCHIZOPHRENIA RESEARCH

Central Nervous System Delivery of the Antipsychotic Olanzapine Induces Hepatic Insulin Resistance

(2010) P. J. F. Martins et al.   DIABETES

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

(2010) Miguel López et al.   NATURE MEDICINE

Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design

(2010) Roberto Coccurello et al.   PHARMACOLOGY & THERAPEUTICS

Preclinical models of antipsychotic drug-induced metabolic side effects

(2010) Heidi N. Boyda et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Olanzapine Long-Acting Injection: A 24-Week, Randomized, Double-Blind Trial of Maintenance Treatment in Patients With Schizophrenia

(2009) John M. Kane et al.   AMERICAN JOURNAL OF PSYCHIATRY

Effects of the antipsychotic drug haloperidol on the somastostatinergic system in SH-SY5Y neuroblastoma cells

(2009) Jana Sánchez-Wandelmer et al.   JOURNAL OF NEUROCHEMISTRY

Antipsychotic drugs upregulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol

(2009) I Kristiana et al.   PHARMACOGENOMICS JOURNAL

Metabolic side effects of antipsychotic drug treatment – pharmacological mechanisms

(2009) Gavin P Reynolds et al.   PHARMACOLOGY & THERAPEUTICS

Hypothalamic Fatty Acid Metabolism Mediates the Orexigenic Action of Ghrelin

(2008) Miguel López et al.   Cell Metabolism

Schizophrenia: A Concise Overview of Incidence, Prevalence, and Mortality

(2008) J. McGrath et al.   EPIDEMIOLOGIC REVIEWS

Olanzapine-induced weight gain: Chronic infusion using osmotic minipumps does not result in stable plasma levels due to degradation of olanzapine in solution

(2008) Esther M. van der Zwaal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroleptics and animal models: feasibility of oral treatment monitored by plasma levels and receptor occupancy assays

(2008) Emma Perez-Costas et al.   JOURNAL OF NEURAL TRANSMISSION

Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver

(2008) Johan Fernø et al.   PSYCHOPHARMACOLOGY

Hyperphagia and increased meal size are responsible for weight gain in rats treated sub-chronically with olanzapine

(2008) Nima Davoodi et al.   PSYCHOPHARMACOLOGY

Antipsychotic effects on estimated 10-year coronary heart disease risk in the CATIE schizophrenia study

(2008) Gail L. Daumit et al.   SCHIZOPHRENIA RESEARCH

AMPK: a metabolic gauge regulating whole-body energy homeostasis

(2008) Ricardo Lage et al.   TRENDS IN MOLECULAR MEDICINE