Salmonella as an Innovative Therapeutic Antitumor Agent

Salmonella-mediated tumor regression involves targeting of tumor myeloid suppressor cells causing a shift to M1-like phenotype and reduction in suppressive capacity

(2014) Suneesh Kaimala et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway

(2014) C-H Lee et al.   GENE THERAPY

Autophagy in Antimicrobial Immunity

(2014) Ligia C. Gomes et al.   MOLECULAR CELL

In Vivo IFN-γ Secretion by NK Cells in Response to Salmonella Typhimurium Requires NLRC4 Inflammasomes

(2014) Andreas Kupz et al.   PLoS One

Connexin 43 Gene Therapy Delivered by Polymer-Modified Salmonella in Murine Tumor Models

(2014) Wei-Kuang Wang et al.   Polymers

Engineered Salmonella typhimurium expressing E7 fusion protein, derived from human papillomavirus, inhibits tumor growth in cervical tumor-bearing mice

(2013) Wonsuck Yoon et al.   BIOTECHNOLOGY LETTERS

Comparison of efficacy ofSalmonella typhimuriumA1-R and chemotherapy on stem-like and non-stem human pancreatic cancer cells

(2013) Yukihiko Hiroshima et al.   CELL CYCLE

Salmonella enhance chemosensitivity in tumor through connexin 43 upregulation

(2013) Wen-Wei Chang et al.   INTERNATIONAL JOURNAL OF CANCER

Virosome Presents Multimodel Cancer Therapy without Viral Replication

(2013) Kotaro Saga et al.   Biomed Research International

Antigen-Specific Bacterial Vaccine Combined with Anti-PD-L1 Rescues Dysfunctional Endogenous T Cells to Reject Long-Established Cancer

(2013) D. C. Binder et al.   Cancer Immunology Research

A polymer coating applied toSalmonellaprevents the binding ofSalmonella-specific antibodies

(2012) Che-Hsin Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Polyfunctional CD4+ T Cell Responses to Immunodominant Epitopes Correlate with Disease Activity of Virulent Salmonella

(2012) Matt Maybeno et al.   PLoS One

Engineering bacteria toward tumor targeting for cancer treatment: current state and perspectives

(2011) Che-Hsin Lee   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

B cells are required for tumor-targeting Salmonella in host

(2011) Che-Hsin Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

T cell augments the antitumor activity of tumor-targeting Salmonella

(2011) Che-Hsin Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis

(2011) S Ganai et al.   CANCER GENE THERAPY

Enhancement of Cancer Vaccine Therapy by Systemic Delivery of a Tumor-Targeting Salmonella-Based STAT3 shRNA Suppresses the Growth of Established Melanoma Tumors

(2011) E. R. Manuel et al.   CANCER RESEARCH

Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain ofSalmonella typhymurium

(2011) Katsuhiro Hayashi et al.   CELL CYCLE

Antibiotic control of tumor-colonizing Salmonella enterica serovar Typhimurium

(2011) Katja Crull et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Vessel destruction by tumor-targetingSalmonella typhimuriumA1-R is enhanced by high tumor vascularity

(2010) Fang Liu et al.   CELL CYCLE

Bacteria-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity

(2010) F. Saccheri et al.   Science Translational Medicine

Targeted therapy of spinal cord glioma with a genetically modifiedSalmonella typhimurium

(2009) H. Kimura et al.   CELL PROLIFERATION

Humoral Immune Responses Inhibit the Antitumor Activities Mediated by Salmonella enterica Serovar choleraesuis

(2009) Che-Hsin Lee et al.   JOURNAL OF IMMUNOTHERAPY

Monotherapy with a Tumor-Targeting Mutant of S. typhimurium Inhibits Liver Metastasis in a Mouse Model of Pancreatic Cancer

(2009) Clinton Yam et al.   JOURNAL OF SURGICAL RESEARCH

Toll-like Receptor 4 Mediates an Antitumor Host Response Induced by Salmonella choleraesuis

(2008) C.-H. Lee et al.   CLINICAL CANCER RESEARCH

Attenuated Salmonella typhimurium with interleukin 2 gene prevents the establishment of pulmonary metastases in a model of osteosarcoma

(2008) Brent S. Sorenson et al.   JOURNAL OF PEDIATRIC SURGERY