Artesunate Reduces Serum Lipopolysaccharide in Cecal Ligation/Puncture Mice via Enhanced LPS Internalization by Macrophages through Increased mRNA Expression of Scavenger Receptors

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

Lipopolysaccharide Clearance, Bacterial Clearance, and Systemic Inflammatory Responses Are Regulated by Cell Type-Specific Functions of TLR4 during Sepsis

(2013) M. Deng et al.   JOURNAL OF IMMUNOLOGY

Dihydromyricetin Reduced Bcl-2 Expression via p53 in Human Hepatoma HepG2 Cells

(2013) Shixing Wu et al.   PLoS One

Sepsis-associated mortality in England: an analysis of multiple cause of death data from 2001 to 2010

(2013) Duncan McPherson et al.   BMJ Open

Inhibition of clathrin/dynamin-dependent internalization interferes with LPS-mediated TRAM–TRIF-dependent signaling pathway

(2012) Yanyan Wang et al.   CELLULAR IMMUNOLOGY

Suppression of TLR4-mediated inflammatory response by macrophage class A scavenger receptor (CD204)

(2011) Koji Ohnishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell-surface nucleolin is involved in lipopolysaccharide internalization and signalling in alveolar macrophages

(2011) Yi Wang et al.   CELL BIOLOGY INTERNATIONAL

Artesunate enhances the antibacterial effect of β-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC

(2011) Bin Li et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

SR-A/MARCO-mediated ligand delivery enhances intracellular TLR and NLR function, but ligand scavenging from cell surface limits TLR4 response to pathogens

(2010) S. Mukhopadhyay et al.   BLOOD

Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism

(2009) Melanie J. Scott et al.   HEPATOLOGY

Artesunate protects sepsis model mice challenged with Staphylococcus aureus by decreasing TNF-α release via inhibition TLR2 and Nod2 mRNA expressions and transcription factor NF-κB activation

(2009) Bin Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Scavenger Receptor BI Protects against Septic Death through Its Role in Modulating Inflammatory Response

(2009) Ling Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

(2009) X. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evasion of macrophage scavenger receptor A-mediated recognition by pathogenic streptococci

(2008) Thomas Areschoug et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-κB activation

(2008) Bin Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

β2-Integrin-induced p38 MAPK Activation Is a Key Mediator in the CD14/TLR4/MD2-dependent Uptake of Lipopolysaccharide by Hepatocytes

(2008) Melanie J. Scott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY