Review
Biophysics
Xueling Xin, Jing Jia, Xiaowen Hu, Yalin Han, Jiwei Liang, Fachun Jiang
Summary: The meta-analysis revealed a significant increase in the risk of dysentery associated with floods in China. Subgroup analysis also showed a significant association between different types of dysentery and floods. This study provides valuable evidence to mitigate the negative health outcomes of floods in China.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2021)
Review
Public, Environmental & Occupational Health
Basilua Andre Muzembo, Kei Kitahara, Debmalya Mitra, Ayumu Ohno, Januka Khatiwada, Shanta Dutta, Shin-Ichi Miyoshi
Summary: This study conducted a meta-analysis to evaluate the prevalence and characteristics of Shigella in Southeast Asia. The findings suggest a high risk of Shigella infection among travelers in this region and highlight the need for effective vaccines.
TRAVEL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Endocrinology & Metabolism
Jie Yao, Wei Tang, Juan Cheng, Xin Li, Qiang Zhou
Summary: This study compared the application value of polymerase chain reaction (PCR), loop-mediated isothermal amplification (LAMP), and bacterial culture in diagnosing bacillary dysentery. The results showed that PCR and LAMP had higher diagnostic accuracy than bacterial culture. This study confirmed that PCR and LAMP had better specificity and sensitivity in detecting Shigella.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Immunology
Irene N. Kasumba, Henry Badji, Helen Powell, M. Jahangir Hossain, Richard Omore, Samba O. Sow, Jennifer R. Verani, James A. Platts-Mills, Marc-Alain Widdowson, Syed M. A. Zaman, Jennifer Jones, Sunil Sen, Jasnehta Permala-Booth, Shamima Nasrin, Anna Roose, Dilruba Nasrin, John Benjamin Ochieng, Jane Juma, Sanogo Doh, Joquina Chiquita M. Jones, Martin Antonio, Alex O. Awuor, Ciara E. Sugerman, Nora Watson, Christopher Focht, Jie Liu, Eric Houpt, Karen L. Kotloff, Sharon M. Tennant
Summary: This study evaluated the burden of Shigella spp in children 0-59 months old with medically attended moderate-to-severe diarrhea. The prevalence of Shigella was found to be high in sub-Saharan Africa, and the strains showed high resistance to commonly used antibiotics while remaining susceptible to ciprofloxacin, ceftriaxone, and azithromycin.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Immunology
Alireza Felegary, Shahram Nazarian, Emad Kordbacheh, Javad Fathi, Mohamad Ebrahim Minae
Summary: This study evaluated the antibody response and protection of a recombinant chimeric protein against Shigella, finding that the protein produced in E. coli could be a promising candidate for vaccine development against Shigella. The chimeric protein showed high antibody response and neutralization ability against the bacterial toxin, providing significant protection in immunized mice against both S. flexneri and S.dysentery.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Environmental Sciences
Ran Zhao, Qi Gao, Qiang Hao, Shuzi Wang, Yiwen Zhang, Hao Li, Baofa Jiang
Summary: The study suggests that humidex may promote the transmission of bacillary dysentery, and this relationship could be modified by factors such as latitude, urbanization rate, natural growth rate of population, and number of primary school students per thousand persons.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biophysics
Li Wang, Chengdong Xu, Gexin Xiao, Jiajun Qiao, Chaozheng Zhang
Summary: This study analyzed the incidence of bacillary dysentery in the Beijing-Tianjin-Hebei region of China in children under 5 years old, revealing a significant spatial heterogeneity of the disease with higher risk in areas with high population densities, such as Beijing and its neighboring regions. There was a positive association between bacillary dysentery and temperature, with hotter temperatures leading to higher relative risks. The effect of temperature on bacillary dysentery peaked at a lag of 3 to 4 days.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Yingshuang Wang, Meina Li, Zhongqi Li, Ruiyu Chai, Xinxin Dong, Han Xu, Jin Wang, Laishun Yao, Yang Zhang, Qinglong Zhao, Yan Yao
Summary: The study on the correlation between temperature and bacterial dysentery in Jilin Province from 2008 to 2018 found a positive correlation between temperature and the disease, with a significant interaction between temperature, humidity, and precipitation under high temperatures (>0 degrees C). This highlights the importance of residents and policymakers paying attention to preventing bacterial dysentery in situations with high temperatures, humidity, and precipitation in temperate monsoon climates.
EPIDEMIOLOGY AND INFECTION
(2021)
Article
Environmental Sciences
Haobo Ni, Qinghui Zeng, Ting Xu, Lina Xiao, Xiaolin Yu, Jinrui Hu, Yang Li, Hualiang Lin, Pi Guo, Haijian Zhou
Summary: Employing empirical dynamic modeling (EDM), this study explored the climate drivers of bacillary dysentery in five temperature zones in China. The findings indicated that the effects of temperature and relative humidity on the disease increase with their respective increments, and their states differ when they reach maximum effects. Furthermore, the negative correlation between temperature and disease incidence strengthens as the temperature zone shifts from temperate to warm temperate to subtropical, with the climate driving effect of the temperate zone being greater than that of the colder and warmer zones. Climate effects only arise when the susceptible pool is large in a single temperature zone. These results provide empirical evidence for the nonlinear complexity of climate factors on bacillary dysentery, which is dependent on susceptible population size and different climate scenarios.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Plant Sciences
Michel Pouofo Nguiam, Steven Collins Njonte Wouamba, Frida Longo, Raceline Gounoue Kamkumo, Larissa Donji Kenne Foweda, Paul Desire Dzeufiet Djomeni, Bruno Lenta Ndjakou, Norbert Sewald, Fabrice Fekam Boyom, Simeon Kouam Fogue, Theophile Dimo
Summary: The study evaluated the efficacy of Xylopia staudtii bark extract against Shigella flexneri infection in immunodepressed mice. The extract showed significant antibacterial activity against Shigella, reducing fecal pathology and mortality rate in mice. It also exhibited anti-inflammatory properties and protected intestinal tissue from damage caused by Shigella infection.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Environmental Sciences
Siqi Ai, Haijian Zhou, Changke Wang, Zhengmin (Min) Qian, Stephen Edward McMillin, Cunrui Huang, Tuantuan Zhang, Lianlian Xu, Zhenjun Li, Hualiang Lin
Summary: The occurrence of bacillary dysentery (BD) is associated with high atmospheric temperature and hot extremes can increase the incidence and disease burden of BD. Vulnerability to hot extremes differs among different regions and populations, with northern residents, females, children, and males being particularly vulnerable during specific types of hot extremes. Approximately 1.854% of BD cases can be attributed to hot extremes, with hot night accounting for a significant proportion.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Infectious Diseases
Nick K. Jones, Trang Nguyen Hoang Thu, Ruklanthi de Alwis, Corinne Thompson, Ha Thanh Tuyen, Tran Do Hoang Nhu, Voong Vinh Phat, Pham Duc Trung, Phung Khanh Lam, Bui Thi Thuy Tien, Hoang Thi Diem Tuyet, Lu Lan Vi, Nguyen Van Vinh Chau, Nhi Le Thi Quynh, Stephen Baker
Summary: The study found a high incidence of exposure to Shigella sonnei in children in Ho Chi Minh City, with a significant reduction in the likelihood of exposure as age increases beyond 2 years.
PLOS NEGLECTED TROPICAL DISEASES
(2023)
Article
Environmental Sciences
Shuzi Wang, Zhidong Liu, Michael Tong, Jianjun Xiang, Ying Zhang, Qi Gao, Yiwen Zhang, Liang Lu, Baofa Jiang, Peng Bi
Summary: This study found that temperature plays the most important role in weather-attributable transmission of bacillary dysentery (BD) in China. The boosted regression tree (BRT) model showed more accurate forecasting for BD dynamics and outbreaks compared to other models, making it a more reliable tool for forecasting and outbreak alert of BD in China.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Infectious Diseases
Yao Zhang, Mengyuan Zhang, Dianju Kang, Wei Sun, Changhong Yang, Rongjie Wei
Summary: Bacillary dysentery (BD) remains a common challenge in Sichuan, especially in the southwest and northwest counties during summer and autumn. Spatial analysis showed that epidemics were mainly concentrated in the northwest and southwest of Sichuan, with high global autocorrelation at the county level. Spatio-temporal scanning revealed yearly clusters of BD, mainly in the southwest and northwest regions of Sichuan, indicating the need for targeted disease prevention and control measures in these areas.
BMC INFECTIOUS DISEASES
(2021)
Article
Immunology
Chin-Shiang Tsai, Kuan-Yin Lin, Bo-Huang Liou, Chien-Shun Chiou, Yi-Chun Lin, Yuan-Ti Lee, Chia-Jui Yang, Hung-Jen Tang, Ying-Shu Liao, Chun-Eng Liu, Chen-Hsiang Lee, Po-Liang Lu, Sung-Hsi Huang, Chien-Ching Hung, Wen-Chien Ko
Summary: Shigellosis has been increasing among men who have sex with men (MSM) and people living with HIV (PLWH) in Taiwan. The dominant strains have changed over the years, with ciprofloxacin-resistant Shigella flexneri 2a becoming the most prevalent in recent years. There is also emerging resistance to cefotaxime. Inappropriate use of antibiotics is common.
EMERGING MICROBES & INFECTIONS
(2022)