The Role of E3 Ubiquitin Ligase Cbl Proteins in β-Elemene Reversing Multi-Drug Resistance of Human Gastric Adenocarcinoma Cells

Increased Akt Signaling Resulting from the Loss of Androgen Responsiveness in Prostate Cancer

(2013) J. Dulinska-Litewka et al.   CURRENT MEDICINAL CHEMISTRY

Signal Transduction Pathways and Transcriptional Mechanisms of ABCB1/Pgp-mediated Multiple Drug Resistance in Human Cancer Cells

(2013) H Sui et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

β-Elemene Induces Apoptosis in Human Renal-cell Carcinoma 786-0 Cells through Inhibition of MAPK/ERK and PI3K/Akt/mTOR Signalling Pathways

(2012) Yun-Hong Zhan et al.   Asian Pacific Journal of Cancer Prevention

Protein tyrosine kinase regulation by ubiquitination: Critical roles of Cbl-family ubiquitin ligases

(2012) Bhopal Mohapatra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Systematic review of β-Elemene injection as adjunctive treatment for lung cancer

(2012) Bin Wang et al.   Chinese Journal of Integrative Medicine

Targeting MDR in breast and lung cancer: Discriminating its potential importance from the failure of drug resistance reversal studies

(2012) Laleh Amiri-Kordestani et al.   DRUG RESISTANCE UPDATES

TRAIL-activated EGFR by Cbl-b-regulated EGFR redistribution in lipid rafts antagonises TRAIL-induced apoptosis in gastric cancer cells

(2012) Ling Xu et al.   EUROPEAN JOURNAL OF CANCER

Evaluation of multidrug resistance in 46 newly diagnosed patients with acute leukemia

(2012) Ana Carolina Rabello de Moraes et al.   Hematology

Roles of ABCB1 gene polymorphisms and haplotype in susceptibility to breast carcinoma risk and clinical outcomes

(2012) Huizhe Wu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Enhancement of cisplatin-induced apoptosis by β-elemene in resistant human ovarian cancer cells

(2012) Qingdi Quentin Li et al.   MEDICAL ONCOLOGY

Reversion of Multidrug Resistance in a Chemoresistant Human Breast Cancer Cell Line by ß-Elemene

(2012) Hong-Bin Xu et al.   PHARMACOLOGY

ABC Transporters: Unvalidated Therapeutic Targets in Cancer and the CNS

(2011) Robert W. Robey et al.   Anti-Cancer Agents in Medicinal Chemistry

Abrogation of Cbl–PI3K Interaction Increases Bone Formation and Osteoblast Proliferation

(2011) Tracy Brennan et al.   CALCIFIED TISSUE INTERNATIONAL

Lysosomal membrane permeabilization contributes to elemene emulsion-induced apoptosis in A549 cells

(2011) Long-Jie Li et al.   FREE RADICAL RESEARCH

β-Elemene Radiosensitizes Lung Cancer A549 Cells by Enhancing DNA Damage and Inhibiting DNA Repair

(2011) Long-Jie Li et al.   PHYTOTHERAPY RESEARCH

β-Elemene Piperazine Derivatives Induce Apoptosis in Human Leukemia Cells through Downregulation of c-FLIP and Generation of ROS

(2011) Zhiying Yu et al.   PLoS One

The Loss of Cbl-Phosphatidylinositol 3-Kinase Interaction Perturbs RANKL-mediated Signaling, Inhibiting Bone Resorption and Promoting Osteoclast Survival

(2010) Naga Suresh Adapala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antineoplastic effect ofβ-elemene on prostate cancer cells and other types of solid tumour cells

(2010) Qingdi Quentin Li et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Reversal of P-glycoprotein-mediated multi-drug resistance by the E3 ubiquitin ligase Cbl-b in human gastric adenocarcinoma cells

(2009) Ye Zhang et al.   JOURNAL OF PATHOLOGY

Akt as a therapeutic target in cancer

(2008) Linda S Steelman et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NFκB pathway

(2007) Byeong Hyeok Choi et al.   CANCER LETTERS