Choosing an Appropriate Infection Model to Study Quorum Sensing Inhibition in Pseudomonas Infections

Synthesis of (R)-norbgugaine and its potential as quorum sensing inhibitor against Pseudomonas aeruginosa

(2013) Mahesh S. Majik et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death

(2013) Natalia V. Kirienko et al.   Cell Host & Microbe

Exploiting Quorum Sensing To Confuse Bacterial Pathogens

(2013) B. LaSarre et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Endemic Malagasy Dalbergia species inhibit quorum sensing in Pseudomonas aeruginosa PAO1

(2013) T. Rasamiravaka et al.   MICROBIOLOGY-SGM

A cell-cell communication signal integrates quorum sensing and stress response

(2013) Jasmine Lee et al.   Nature Chemical Biology

Ellagic Acid Derivatives from Terminalia chebula Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate Pseudomonas aeruginosa PAO1 Virulence

(2013) Sajal Sarabhai et al.   PLoS One

Systemic Inflammatory Responses and Multiple Organ Dysfunction Syndrome Following Skin Burn Wound and Pseudomonas aeruginosa Infection in Mice

(2013) Na Li et al.   SHOCK

Caenorhabditis elegans reveals novel Pseudomonas aeruginosa virulence mechanism

(2013) Putri Dwi Utari et al.   TRENDS IN MICROBIOLOGY

Identification of Pseudomonas aeruginosa Phenazines that Kill Caenorhabditis elegans

(2013) Brent Cezairliyan et al.   PLoS Pathogens

New Life for an Old Drug: the Anthelmintic Drug Niclosamide Inhibits Pseudomonas aeruginosa Quorum Sensing

(2012) F. Imperi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ajoene, a Sulfur-Rich Molecule from Garlic, Inhibits Genes Controlled by Quorum Sensing

(2012) Tim Holm Jakobsen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Food as a Source for Quorum Sensing Inhibitors: Iberin from Horseradish Revealed as a Quorum Sensing Inhibitor of Pseudomonas aeruginosa

(2012) Tim Holm Jakobsen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Orally Administered ThermostableN-Acyl Homoserine Lactonase from Bacillus sp. Strain AI96 Attenuates Aeromonas hydrophila Infection in Zebrafish

(2012) Yanan Cao et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Quorum sensing inhibitors: An overview

(2012) Vipin Chandra Kalia   BIOTECHNOLOGY ADVANCES

Eugenol inhibits quorum sensing at sub-inhibitory concentrations

(2012) Liman Zhou et al.   BIOTECHNOLOGY LETTERS

A Streptococcus pneumoniae infection model in larvae of the wax moth Galleria mellonella

(2012) B. A. Evans et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Mutations That Impact the Enteropathogenic Escherichia coli Cpx Envelope Stress Response Attenuate Virulence in Galleria mellonella

(2012) S. Leuko et al.   INFECTION AND IMMUNITY

Legionella pneumophila Pathogenesis in the Galleria mellonella Infection Model

(2012) Clare R. Harding et al.   INFECTION AND IMMUNITY

Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: a randomized controlled trial

(2012) Christian van Delden et al.   INTENSIVE CARE MEDICINE

Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model

(2012) L. D. Christensen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Garlic ointment inhibits biofilm formation by bacterial pathogens from burn wounds

(2012) P. Nidadavolu et al.   JOURNAL OF MEDICAL MICROBIOLOGY

A new quorum-sensing inhibitor attenuates virulence and decreases antibiotic resistance in Pseudomonas aeruginosa

(2012) Yu-Xiang Yang et al.   JOURNAL OF MICROBIOLOGY

Galleria mellonella as aModel for Studying Enterococcus faecium Host Persistence

(2012) François Lebreton et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Tasco®: A Product of Ascophyllum nodosum Enhances Immune Response of Caenorhabditis elegans Against Pseudomonas aeruginosa Infection

(2012) Saveetha Kandasamy et al.   Marine Drugs

The non-mammalian hostGalleria mellonellacan be used to study the virulence of the fungal pathogenCandida tropicalisand the efficacy of antifungal drugs during infection by this pathogenic yeast

(2012) Ana Cecilia Mesa-Arango et al.   MEDICAL MYCOLOGY

Lethality and cooperation of Pseudomonas aeruginosa quorum-sensing mutants in Drosophila melanogaster infection models

(2012) E. I. Lutter et al.   MICROBIOLOGY-SGM

Inhibition of Biofilm Formation, Quorum Sensing and Infection in Pseudomonas aeruginosa by Natural Products-Inspired Organosulfur Compounds

(2012) Nathaniel C. Cady et al.   PLoS One

Inhibition of Quorum Sensing-Controlled Virulence Factor Production in Pseudomonas aeruginosa PAO1 by Ayurveda Spice Clove (Syzygium Aromaticum) Bud Extract

(2012) Thiba Krishnan et al.   SENSORS

Fusarium pathogenesis investigated using Galleria mellonella as a heterologous host

(2011) Jeffrey J. Coleman et al.   Fungal Biology

Quorum quenching quandary: resistance to antivirulence compounds

(2011) Toshinari Maeda et al.   ISME Journal

Wax moth larva (Galleria mellonella): an in vivo model for assessing the efficacy of antistaphylococcal agents

(2011) A. P. Desbois et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

PA0305 of Pseudomonas aeruginosa is a quorum quenching acylhomoserine lactone acylase belonging to the Ntn hydrolase superfamily

(2011) M. Wahjudi et al.   MICROBIOLOGY-SGM

The Pseudomonas aeruginosa Autoinducer 3O-C12 Homoserine Lactone Provokes Hyperinflammatory Responses from Cystic Fibrosis Airway Epithelial Cells

(2011) Matthew L. Mayer et al.   PLoS One

A Novel Metagenomic Short-Chain Dehydrogenase/Reductase Attenuates Pseudomonas aeruginosa Biofilm Formation and Virulence on Caenorhabditis elegans

(2011) Patrick Bijtenhoorn et al.   PLoS One

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model

(2011) S. Limmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre-exposure ofGalleria mellonellalarvae to different doses ofAspergillus fumigatusconidia causes differential activation of cellular and humoral immune responses

(2011) John P. Fallon et al.   Virulence

Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways

(2010) Warren R. J. D. Galloway et al.   CHEMICAL REVIEWS

Pseudomonas aeruginosa pvdQ Gene Prevents Caco-2 Cells from Obstruction of Quorum-Sensing Signal

(2010) Lu Ye et al.   CURRENT MICROBIOLOGY

Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections

(2010) A. Bala et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Secretion of Pseudomonas aeruginosa type III cytotoxins is dependent on pseudomonas quinolone signal concentration

(2010) G. Singh et al.   MICROBIAL PATHOGENESIS

Molecular pathogenesis of Listeria monocytogenes in the alternative model host Galleria mellonella

(2010) S. A. Joyce et al.   MICROBIOLOGY-SGM

In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

(2010) Thomas Bjarnsholt et al.   Nature Protocols

Quorum Sensing and Virulence of Pseudomonas aeruginosa during Lung Infection of Cystic Fibrosis Patients

(2010) Thomas Bjarnsholt et al.   PLoS One

Duckweed (Lemna minor) as a Model Plant System for the Study of Human Microbial Pathogenesis

(2010) Yong Zhang et al.   PLoS One

A unique regulator controls the activation threshold of quorum-regulated genes inPseudomonas aeruginosa

(2010) Richard Siehnel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What can Dictyostelium bring to the study of Pseudomonas infections?

(2010) Wanessa C. Lima et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Quorum-Quenching Acylase Reduces the Virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans Infection Model

(2009) E. Papaioannou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Galleria mellonella as a Model System To Study Acinetobacter baumannii Pathogenesis and Therapeutics

(2009) A. Y. Peleg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Galleria mellonella as a Model System for Studying Listeria Pathogenesis

(2009) K. Mukherjee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structural understanding of quorum-sensing inhibitors by molecular modeling study in Pseudomonas aeruginosa

(2009) Cheoljin Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Dioxygenase-Mediated Quenching of Quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

(2009) Christian Pustelny et al.   CHEMISTRY & BIOLOGY

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

(2009) Paul Williams et al.   CURRENT OPINION IN MICROBIOLOGY

Garlic blocks quorum sensing and attenuates the virulence ofPseudomonas aeruginosa

(2009) Kusum Harjai et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Pseudomonas aeruginosa Infection of Zebrafish Involves both Host and Pathogen Determinants

(2009) A. E. Clatworthy et al.   INFECTION AND IMMUNITY

Quorum sensing and social networking in the microbial world

(2009) S. Atkinson et al.   Journal of the Royal Society Interface

Revisiting the quorum-sensing hierarchy in Pseudomonas aeruginosa: the transcriptional regulator RhlR regulates LasR-specific factors

(2009) V. Dekimpe et al.   MICROBIOLOGY-SGM

Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection

(2009) Yiorgos Apidianakis et al.   Nature Protocols

The type III secretion system of Pseudomonas aeruginosa: infection by injection

(2009) Alan R. Hauser   NATURE REVIEWS MICROBIOLOGY

Red death in Caenorhabditis elegans caused by Pseudomonas aeruginosa PAO1

(2009) A. Zaborin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel vertebrate model ofStaphylococcus aureusinfection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens

(2008) Tomasz K. Prajsnar et al.   CELLULAR MICROBIOLOGY

Significant immunomodulatory effects ofPseudomonas aeruginosaquorum-sensing signal molecules: possible link in human sepsis

(2008) Pisake Boontham et al.   CLINICAL SCIENCE

Antibacterial activity in vivo and in vitro in the hemolymph of Galleria mellonella infected with Pseudomonas aeruginosa

(2008) Mariola Andrejko et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Development of Galleria mellonella as an Alternative Infection Model for the Burkholderia cepacia Complex

(2008) K. D. Seed et al.   INFECTION AND IMMUNITY

Animal models of chronic lung infection with Pseudomonas aeruginosa: useful tools for cystic fibrosis studies

(2008) I Kukavica-Ibrulj et al.   LABORATORY ANIMALS

Role of quorum sensing by Pseudomonas aeruginosa in microbial keratitis and cystic fibrosis

(2008) M. D. P. Willcox et al.   MICROBIOLOGY-SGM

An alternative insect pathogenic strategy in an Aspergillus flavus auxotroph

(2008) Lisa R. Scully et al.  

Changes in Galleria mellonella apolipophorin III level during Pseudomonas aeruginosa infection

(2007) Mariola Andrejko et al.   JOURNAL OF INVERTEBRATE PATHOLOGY