Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 14, Issue 11, Pages 21805-21818Publisher
MDPI
DOI: 10.3390/ijms141121805
Keywords
Artemia salina; Daphnia magna; Triticum aestivum; pyrazolyl thiourea
Funding
- National Authority for Scientific Research of Romania, through CNCSIS-UEFISCDI [PN-II-RU-TE-2011-3-0228]
Ask authors/readers for more resources
New pyrazole derivatives were designed and synthesized as potential protein kinase inhibitors in the view to develop specific antitumor therapies. The structures of the compounds were elucidated using spectral and elemental analyses. The antitumor potential was estimated using wheat seeds and the general toxicity was evaluated by alternative methods, using invertebrate animals. One 3-aminopyrazole derivative emerged as a potential candidate for the development of future cytotoxic compounds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available