Acidosis Decreases c-Myc Oncogene Expression in Human Lymphoma Cells: A Role for the Proton-Sensing G Protein-Coupled Receptor TDAG8

Acidosis Activation of the Proton-Sensing GPR4 Receptor Stimulates Vascular Endothelial Cell Inflammatory Responses Revealed by Transcriptome Analysis

(2013) Lixue Dong et al.   PLoS One

Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments

(2012) Jonathan W. Wojtkowiak et al.   CANCER RESEARCH

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Activation of T cell death-associated gene 8 regulates the cytokine production of T cells and macrophages in vitro

(2012) Yoshiko Onozawa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Comparative study of 3D morphology and functions on genetically engineered mouse melanoma cells

(2012) Ying Zhang et al.   Integrative Biology

Acidosis Promotes Bcl-2 Family-mediated Evasion of Apoptosis

(2012) Christopher Ryder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Is a Protective Mechanism for Human Melanoma Cells under Acidic Stress

(2012) Maria Lucia Marino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

“Hyper-Warburgism,” a Cause of Asymptomatic Hypoglycemia with Lactic Acidosis in a Patient with Non-Hodgkin's Lymphoma

(2012) Georges C. Elhomsy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Positron Emission Tomographic Scans in Lymphoma: Convention and Controversy

(2012) Stephen M. Ansell et al.   MAYO CLINIC PROCEEDINGS

Involvement of proton-sensing receptor TDAG8 in the anti-inflammatory actions of dexamethasone in peritoneal macrophages

(2011) Xiao-dong He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of tumor cell migration and metastasis by the proton-sensing GPR4 receptor

(2011) Reid D. Castellone et al.   CANCER LETTERS

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

Activation of GPR4 by Acidosis Increases Endothelial Cell Adhesion through the cAMP/Epac Pathway

(2011) Aishe Chen et al.   PLoS One

Targeting MYC dependence in cancer by inhibiting BET bromodomains

(2011) J. A. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type B Lactic Acidosis Secondary to Malignancy: Case Report, Review of Published Cases, Insights into Pathogenesis, and Prospects for Therapy

(2011) Juan P. Ruiz et al.   TheScientificWorldJOURNAL

Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity

(2010) Kieran Smallbone et al.   Biology Direct

Myc-Nick: A Cytoplasmic Cleavage Product of Myc that Promotes α-Tubulin Acetylation and Cell Differentiation

(2010) Maralice Conacci-Sorrell et al.   CELL

Each one of certain histidine residues in G-protein-coupled receptor GPR4 is critical for extracellular proton-induced stimulation of multiple G-protein-signaling pathways

(2010) Jin-Peng Liu et al.   PHARMACOLOGICAL RESEARCH

The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor

(2010) Y. Ihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging of tumor glucose utilization with positron emission tomography

(2008) Andrea Buerkle et al.   CANCER AND METASTASIS REVIEWS

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc–Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

(2008) Jianxia Guo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers

(2008) Julia Ling-Yu Chen et al.   PLoS Genetics