Arsenic Trioxide Inhibits Cell Growth and Induces Apoptosis through Inactivation of Notch Signaling Pathway in Breast Cancer

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Changing Concepts: Menopausal Hormone Therapy and Breast Cancer

(2012) R. T. Chlebowski et al.   JNCI-Journal of the National Cancer Institute

Arsenic Trioxide Enhances the Radiation Sensitivity of Androgen-Dependent and -Independent Human Prostate Cancer Cells

(2012) Hui-Wen Chiu et al.   PLoS One

Arsenic Trioxide Treatment Decreases the Oxygen Consumption Rate of Tumor Cells and Radiosensitizes Solid Tumors

(2011) C. Diepart et al.   CANCER RESEARCH

Arsenic trioxide inhibits invasion/migration in SGC-7901 cells by activating the reactive oxygen species-dependent cyclooxygenase-2/matrix metalloproteinase-2 pathway

(2011) Yingxia Liu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2

(2011) António Carlos Ferreira et al.   HUMAN MOLECULAR GENETICS

Notch-1 and Notch-4 Biomarker Expression in Triple-Negative Breast Cancer

(2011) Jodi Speiser et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Impact of arsenic trioxide in the treatment of acute promyelocytic leukemia

(2011) E Lengfelder et al.   LEUKEMIA

Notch1 Inhibition Alters the CD44hi/CD24lo Population and Reduces the Formation of Brain Metastases from Breast Cancer

(2011) P. M. McGowan et al.   MOLECULAR CANCER RESEARCH

Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer

(2011) M Kondratyev et al.   ONCOGENE

Arsenic trioxide — An old drug rediscovered

(2010) Ashkan Emadi et al.   BLOOD REVIEWS

Arsenic trioxide inhibits osteosarcoma cell invasiveness via MAPK signaling pathway

(2010) Ren Tingting et al.   CANCER BIOLOGY & THERAPY

Downregulation of Notch Pathway by a  -Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model

(2010) C. L. Efferson et al.   CANCER RESEARCH

Breast Cancer Stem Cells: Something Out of Notching?

(2010) H. Harrison et al.   CANCER RESEARCH

Notch-1 and Notch-4 Receptors as Prognostic Markers in Breast Cancer

(2010) Katharine Yao et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Essential role of cell cycle regulatory genes p21 and p27 expression in inhibition of breast cancer cells by arsenic trioxide

(2010) Xi Wang et al.   MEDICAL ONCOLOGY

Arsenic trioxide-mediated Notch pathway inhibition depletes the cancer stem-like cell population in gliomas

(2009) Yunbo Zhen et al.   CANCER LETTERS

TW-37, a Small-Molecule Inhibitor of Bcl-2, Inhibits Cell Growth and Induces Apoptosis in Pancreatic Cancer: Involvement of Notch-1 Signaling Pathway

(2009) Z. Wang et al.   CANCER RESEARCH

HER-2, Notch, and Breast Cancer Stem Cells: Targeting an Axis of Evil

(2009) H. Korkaya et al.   CLINICAL CANCER RESEARCH

Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells

(2009) H. M. Pettersson et al.   MOLECULAR CANCER THERAPEUTICS

Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

(2008) P. Rizzo et al.   CANCER RESEARCH

Therapeutic Potential of γ -Secretase Inhibitors and Modulators

(2008) Bruno Imbimbo   CURRENT TOPICS IN MEDICINAL CHEMISTRY

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor

(2008) C Osipo et al.   ONCOGENE