Noncanonical Reactions of Flavoenzymes

Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation

(2012) Richa Dhatwalia et al.   BIOCHEMISTRY

Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic FungusAspergillus fumigatus

(2012) Richa Dhatwalia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase fromAspergillus fumigatus

(2012) Karin E. van Straaten et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Mechanism of UDP-Galactopyranose Mutase from Trypanosoma cruzi: A Potential Drug Target against Chagas' Disease

(2012) Michelle Oppenheimer et al.   PLoS One

Isolation and characterization of functional Leishmania major virulence factor UDP-galactopyranose mutase

(2011) Michelle Oppenheimer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stereochemical Studies of the Type II Isopentenyl Diphosphate-Dimethylallyl Diphosphate Isomerase Implicate the FMN Coenzyme in Substrate Protonation

(2011) Jordi Calveras et al.   CHEMBIOCHEM

Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase

(2011) He G. Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus

(2010) Michelle Oppenheimer et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Aspergillus fumigatusSidA Is a Highly Specific Ornithine Hydroxylase with Bound Flavin Cofactor

(2010) Samuel W. Chocklett et al.   BIOCHEMISTRY

Linear Free Energy Relationships Demonstrate a Catalytic Role for the Flavin Mononucleotide Coenzyme of the Type II Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase

(2010) Christopher J. Thibodeaux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal Structures of Intermediates in the Nitroalkane Oxidase Reaction†‡

(2009) Annie Héroux et al.   BIOCHEMISTRY

X-ray Crystallography Reveals a Reduced Substrate Complex of UDP-Galactopyranose Mutase Poised for Covalent Catalysis by Flavin,

(2009) Todd D. Gruber et al.   BIOCHEMISTRY

New Role of Flavin as a General Acid-Base Catalyst with No Redox Function in Type 2 Isopentenyl-diphosphate Isomerase

(2009) Hideaki Unno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Substrate Binding to UDP-galactopyranose Mutase: Crystal Structures in the Reduced and Oxidized State Complexed with UDP-galactopyranose and UDP

(2009) Sarathy Karunan Partha et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of Type 2 Isopentenyl Diphosphate Isomerase fromThermus thermophilusin Complex with Inorganic Pyrophosphate†

(2008) Jérôme de Ruyck et al.   BIOCHEMISTRY

Evidence for the Involvement of Acid/Base Chemistry in the Reaction Catalyzed by the Type II Isopentenyl Diphosphate/Dimethylallyl Diphosphate Isomerase fromStaphylococcus aureus†

(2008) Christopher J. Thibodeaux et al.   BIOCHEMISTRY

Contribution of Galactofuranose to the Virulence of the Opportunistic PathogenAspergillus fumigatus

(2008) Philipp S. Schmalhorst et al.   EUKARYOTIC CELL

Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity

(2008) Gernot Rauch et al.   FEBS Journal

Type II Isopentenyl Diphosphate Isomerase:  Irreversible Inactivation by Covalent Modification of Flavin

(2008) Steven C. Rothman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY