Molecular Mechanisms of Aging and Immune System Regulation in Drosophila

Pharmacological inhibition of NF-κB prolongs lifespan of Drosophila melanogaster

(2016) Alexey Moskalev et al.   Aging-US

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

(2014) Anne Simonsen et al.   Autophagy

The fruit fly Drosophila melanogaster unfolds the secrets of innate immunity

(2012) Mika Rämet   ACTA PAEDIATRICA

Phosphoinositide Binding by the Toll Adaptor dMyD88 Controls Antibacterial Responses in Drosophila

(2012) Lorri R. Marek et al.   IMMUNITY

The small heat shock proteins family: The long forgotten chaperones

(2012) C. Garrido et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The p53 network: cellular and systemic DNA damage responses in aging and cancer

(2012) H. Christian Reinhardt et al.   TRENDS IN GENETICS

Positive and negative regulation of the Drosophila immune response

(2011) Kamna Aggarwal et al.   BMB Reports

Senescence of the cellular immune response in Drosophila melanogaster

(2011) Danielle K. Mackenzie et al.   EXPERIMENTAL GERONTOLOGY

Drosophila cellular immunity: a story of migration and adhesion

(2011) M.-O. Fauvarque et al.   JOURNAL OF CELL SCIENCE

The Drosophila Toll Signaling Pathway

(2011) S. Valanne et al.   JOURNAL OF IMMUNOLOGY

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

Immune Responses Accelerate Ageing: Proof-of-Principle in an Insect Model

(2011) E. Rhiannon Pursall et al.   PLoS One

ATP-sensitive potassium channel (KATP)-dependent regulation of cardiotropic viral infections

(2011) I. Eleftherianos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spermidine: A novel autophagy inducer and longevity elixir

(2010) Frank Madeo et al.   Autophagy

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Age- and Diet-Specific Effects of Variation at S6 Kinase on Life History, Metabolic, and Immune Response Traits in Drosophila melanogaster

(2010) Irene Cho et al.   DNA AND CELL BIOLOGY

Heat shock proteins and Drosophila aging

(2010) John Tower   EXPERIMENTAL GERONTOLOGY

dSir2 and longevity in Drosophila

(2010) Stewart Frankel et al.   EXPERIMENTAL GERONTOLOGY

Drosophila as a model to study age-related neurodegenerative disorders: Alzheimer's disease

(2010) Julia Maeve Bonner et al.   EXPERIMENTAL GERONTOLOGY

Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network

(2010) Linda Partridge et al.   EXPERIMENTAL GERONTOLOGY

The Role of Mitochondria in Drosophila Aging

(2010) Jaehyoung Cho et al.   EXPERIMENTAL GERONTOLOGY

Survival costs of reproduction in Drosophila

(2010) Thomas Flatt   EXPERIMENTAL GERONTOLOGY

Regulation of Drosophila lifespan by JNK signaling

(2010) Benoit Biteau et al.   EXPERIMENTAL GERONTOLOGY

Drosophila as a model for age-related impairment in locomotor and other behaviors

(2010) Melanie A. Jones et al.   EXPERIMENTAL GERONTOLOGY

Drosophila as a model to study cardiac aging

(2010) Mayuko Nishimura et al.   EXPERIMENTAL GERONTOLOGY

Dissecting the genetics of longevity inDrosophila melanogaster

(2010) Annalise B. Paaby et al.   FLY

Wolbachia symbiosis and insect immune response

(2010) Stefanos Siozios et al.   Insect Science

Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?

(2010) M. D. W. Piper et al.   JOURNAL OF INTERNAL MEDICINE

FOXO-dependent regulation of innate immune homeostasis

(2010) Thomas Becker et al.   NATURE

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies

(2010) J. H. Lee et al.   SCIENCE

Phylogeny and Function of the Invertebrate p53 Superfamily

(2010) R. Rutkowski et al.   Cold Spring Harbor Perspectives in Biology

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

(2010) Sebastian Grönke et al.   PLoS Genetics

Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk

(2010) Cathy Slack et al.   PLoS Genetics

Combined effects of suppressing live yeast and of a cold pretreatment on longevity, aging and resistance to several stresses in Drosophila melanogaster

(2009) Éric Le Bourg   BIOGERONTOLOGY

The immune response attenuates growth and nutrient storage in Drosophila by reducing insulin signaling

(2009) J. R. DiAngelo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin and JNK: optimizing metabolic homeostasis and lifespan

(2009) Jason Karpac et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

NF- B in the Immune Response of Drosophila

(2009) C. Hetru et al.   Cold Spring Harbor Perspectives in Biology

Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response

(2008) Maria E. Giannakou et al.   AGING CELL

Drosophila lifespan control by dietary restriction independent of insulin-like signaling

(2008) Kyung-Jin Min et al.   AGING CELL

Functional analysis of the Drosophila immune response during aging

(2008) Sean Ramsden et al.   AGING CELL

Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction

(2008) William Mair et al.   Annual Review of Biochemistry

Cold stress increases resistance to fungal infection throughout life in Drosophila melanogaster

(2008) Éric Le Bourg et al.   BIOGERONTOLOGY

Models of infectious diseases in the fruit fly Drosophila melanogaster

(2008) M. S. Dionne et al.   Disease Models & Mechanisms

Conditional inhibition of autophagy genes in adult Drosophila impairs immunity without compromising longevity

(2008) Chunli Ren et al.   EXPERIMENTAL GERONTOLOGY

Immune reactions of insects on bacterial pathogens and mutualists

(2008) Heike Feldhaar et al.   MICROBES AND INFECTION

Toll-like receptors — taking an evolutionary approach

(2008) François Leulier et al.   NATURE REVIEWS GENETICS

Autophagy and aging: keeping that old broom working

(2008) Ana Maria Cuervo   TRENDS IN GENETICS