Curcumin: Updated Molecular Mechanisms and Intervention Targets in Human Lung Cancer

Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer

(2014) Kwang Woon Kim et al.   Autophagy

Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

(2012) Wen Cai Zhang et al.   CELL

STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells

(2011) Li Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells

(2011) Giampietro Viola et al.   BIOCHEMICAL PHARMACOLOGY

Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030

(2011) L Lin et al.   BRITISH JOURNAL OF CANCER

Lung cancer: New biological insights and recent therapeutic advances

(2011) Suresh S. Ramalingam et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors

(2011) Kah Jing Lim et al.   CANCER BIOLOGY & THERAPY

Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression

(2011) B. Bao et al.   CANCER RESEARCH

Curcumin Induces Small Cell Lung Cancer NCI-H446 Cell Apoptosis via the Reactive Oxygen Species-Mediated Mitochondrial Pathway and Not the Cell Death Receptor Pathway

(2011) Cheng-Liang Yang et al.   DNA AND CELL BIOLOGY

Curcumin enhanced adriamycin-induced human liver-derived Hepatoma G2 cell death through activation of mitochondria-mediated apoptosis and autophagy

(2011) Haoran Qian et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

miR-1254 and miR-574-5p: Serum-Based microRNA Biomarkers for Early-Stage Non-small Cell Lung Cancer

(2011) Kristen M. Foss et al.   Journal of Thoracic Oncology

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

(2011) Reason Wilken et al.   Molecular Cancer

The cancer stem cell: premises, promises and challenges

(2011) Hans Clevers   NATURE MEDICINE

EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells

(2011) Weidong Han et al.   PLoS One

Curcumin Induces EGFR Degradation in Lung Adenocarcinoma and Modulates p38 Activation in Intestine: The Versatile Adjuvant for Gefitinib Therapy

(2011) Jen-Yi Lee et al.   PLoS One

Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway

(2010) Jian Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt/β-catenin signaling regulates cancer stem cells in lung cancer A549 cells

(2010) Ying Teng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthesis of novel oxime-containing pyrazole derivatives and discovery of regulators for apoptosis and autophagy in A549 lung cancer cells

(2010) Liang-Wen Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer

(2010) Giridhar Mudduluru et al.   BIOSCIENCE REPORTS

The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor

(2010) Roberta Riccioni et al.   BLOOD CELLS MOLECULES AND DISEASES

Development of curcumin as an epigenetic agent

(2010) Siqing Fu et al.   CANCER

Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC

(2010) Alexa B. Turke et al.   CANCER CELL

Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: Towards targeting of cancer stem cells with phytochemicals

(2010) Dunne Fong et al.   CANCER LETTERS

Gemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF

(2010) Shadan Ali et al.   CANCER RESEARCH

let-7 and miR-17-92: Small-sized major players in lung cancer development

(2010) Hirotaka Osada et al.   CANCER SCIENCE

An Overview of Concepts for Cancer Stem Cells

(2010) Shih-Yin Chen et al.   CELL TRANSPLANTATION

Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis

(2010) Linlang Guo et al.   EUROPEAN JOURNAL OF CANCER

Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers

(2010) Lei Yu et al.   INTERNATIONAL JOURNAL OF CANCER

miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines

(2010) Wei Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

Lung Adenocarcinoma From East Asian Never-Smokers Is a Disease Largely Defined by Targetable Oncogenic Mutant Kinases

(2010) Yihua Sun et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular Predictors of Sensitivity to the MET Inhibitor PHA665752 in Lung Carcinoma Cells

(2010) Daisuke Matsubara et al.   Journal of Thoracic Oncology

Drugs that Target Specificity Proteins Downregulate Epidermal Growth Factor Receptor in Bladder Cancer Cells

(2010) Gayathri Chadalapaka et al.   MOLECULAR CANCER RESEARCH

Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway

(2010) Zhang   ONCOLOGY REPORTS

Cancer stem cells in solid tumors

(2010) Patrick C. Hermann et al.   SEMINARS IN CANCER BIOLOGY

Synthesis of novel pyrazole carboxamide derivatives and discovery of modulators for apoptosis or autophagy in A549 lung cancer cells

(2009) Xiao-Ling Ding et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-κB inhibitor, DMAPT (LC-1)

(2009) Sundar Neelakantan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

(2009) Madhuri Kakarala et al.   BREAST CANCER RESEARCH AND TREATMENT

Curcumin induces apoptosis-independent death in oesophageal cancer cells

(2009) G O'Sullivan-Coyne et al.   BRITISH JOURNAL OF CANCER

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Curcumin Sensitizes Lung Cancer Cells to Cisplatin-Induced Apoptosis Through Superoxide Anion-Mediated Bcl-2 Degradation

(2009) Pithi Chanvorachote et al.   CANCER INVESTIGATION

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)

(2009) Song-Shei Lin et al.   CANCER LETTERS

Evaluation of MicroRNA Expression Profiles That May Predict Recurrence of Localized Stage I Non-Small Cell Lung Cancer after Surgical Resection

(2009) S. K. Patnaik et al.   CANCER RESEARCH

Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells

(2009) Yan-Li Jia et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Cancer stem cell: Implications in cancer biology and therapy with special reference to lung cancer

(2009) Hitoshi Kitamura et al.   LUNG CANCER

Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells

(2009) Jie Yang et al.   MEDICAL ONCOLOGY

Curcumin modulates eukaryotic initiation factors in human lung adenocarcinoma epithelial cells

(2009) Lixia Chen et al.   MOLECULAR BIOLOGY REPORTS

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer

(2009) Rafael Rosell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Can we finally target the leukemic stem cells?

(2008) Craig T. Jordan   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

MicroRNA Signature Predicts Survival and Relapse in Lung Cancer

(2008) Sung-Liang Yu et al.   CANCER CELL

Side population cells in human cancers

(2008) Colleen Wu et al.   CANCER LETTERS

Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor-Activating Mutations

(2008) S. Yano et al.   CANCER RESEARCH

Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

(2008) J. A. Engelman et al.   CLINICAL CANCER RESEARCH

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

(2008) N. Dhillon et al.   CLINICAL CANCER RESEARCH

Knockdown of integrin β4-induced autophagic cell death associated with P53 in A549 lung adenocarcinoma cells

(2008) Qiuxia He et al.   FEBS Journal

First-Line Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring SomaticEGFRMutations

(2008) Lecia V. Sequist et al.   JOURNAL OF CLINICAL ONCOLOGY

Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells

(2008) M. Sun et al.   MOLECULAR CANCER THERAPEUTICS

BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models

(2008) D Li et al.   ONCOGENE

MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer

(2008) M Garofalo et al.   ONCOGENE

Drug-Selected Human Lung Cancer Stem Cells: Cytokine Network, Tumorigenic and Metastatic Properties

(2008) Vera Levina et al.   PLoS One