Anchoring Intrinsically Disordered Proteins to Multiple Targets: Lessons from N-Terminus of the p53 Protein

Molecular Modeling Studies of Peptide Inhibitors Highlight the Importance of Conformational Prearrangement for Inhibition of Calpain

(2010) Wanting Jiao et al.   BIOCHEMISTRY

Unique Physical Properties and Interactions of the Domains of Methylated DNA Binding Protein 2

(2010) Rajarshi P. Ghosh et al.   BIOCHEMISTRY

Understanding protein non-folding

(2010) Vladimir N. Uversky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Hub Promiscuity in Protein-Protein Interaction Networks

(2010) Ashwini Patil et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Computational Mapping of Anchoring Spots on Protein Surfaces

(2010) Avraham Ben-Shimon et al.   JOURNAL OF MOLECULAR BIOLOGY

Systematic Mutational Analysis of Peptide Inhibition of the p53–MDM2/MDMX Interactions

(2010) Chong Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein

(2010) Stéphane Gely et al.   JOURNAL OF MOLECULAR RECOGNITION

Nonnative Interactions in Coupled Folding and Binding Processes of Intrinsically Disordered Proteins

(2010) Yongqi Huang et al.   PLoS One

Protein interface conservation across structure space

(2010) Q. C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP

(2010) Magnus Kjaergaard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The protein kingdom extended: Ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation

(2010) Konstantin K. Turoverov et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Side-chain rotamer transitions at protein-protein interfaces

(2010) Mainak Guharoy et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Smoothing molecular interactions: The “kinetic buffer” effect of intrinsically disordered proteins

(2010) Yongqi Huang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural Diversity in Free and Bound States of Intrinsically Disordered Protein Phosphatase 1 Regulators

(2010) Joseph A. Marsh et al.   STRUCTURE

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

(2010) Peter Csermely et al.   TRENDS IN BIOCHEMICAL SCIENCES

The MDM2-Binding Region in the Transactivation Domain of p53 Also Acts as a Bcl-XL-Binding Motif

(2009) Huibin Xu et al.   BIOCHEMISTRY

The Structural Basis of Pregnane X Receptor Binding Promiscuity

(2009) Chi-Ho Ngan et al.   BIOCHEMISTRY

Modulation of p53 binding to MDM2: computational studies reveal important roles of Tyr100

(2009) Shubhra Dastidar et al.   BMC BIOINFORMATICS

Predicting intrinsic disorder in proteins: an overview

(2009) Bo He et al.   CELL RESEARCH

Biophysical characterization of intrinsically disordered proteins

(2009) David Eliezer   CURRENT OPINION IN STRUCTURAL BIOLOGY

Kinetic Advantage of Intrinsically Disordered Proteins in Coupled Folding–Binding Process: A Critical Assessment of the “Fly-Casting” Mechanism

(2009) Yongqi Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

Atomistic Details of the Disordered States of KID and pKID. Implications in Coupled Binding and Folding

(2009) Debabani Ganguly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin

(2009) T. Wlodarski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Residual structure within the disordered C-terminal segment of p21Waf1/Cip1/Sdi1and its implications for molecular recognition

(2009) Mi-Kyung Yoon et al.   PROTEIN SCIENCE

Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation

(2009) Hanqiao Feng et al.   STRUCTURE

Forces mediating protein–protein interactions: a computational study of p53 “approaching” MDM2

(2009) Shubhra Ghosh Dastidar et al.   THEORETICAL CHEMISTRY ACCOUNTS

Mechanism of Fast Peptide Recognition by SH3 Domains

(2008) Mazen Ahmad et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Biology of the Tumor Suppressor p53

(2008) Andreas C. Joerger et al.   Annual Review of Biochemistry

Detailed Structural Characterization of Unbound Protein Phosphatase 1 Inhibitors†

(2008) Barbara Dancheck et al.   BIOCHEMISTRY

Regulation of Cell Division by Intrinsically Unstructured Proteins: Intrinsic Flexibility, Modularity, and Signaling Conduits†

(2008) Charles A. Galea et al.   BIOCHEMISTRY

Restricted Mobility of Conserved Residues in Protein-Protein Interfaces in Molecular Simulations

(2008) Osman N. Yogurtcu et al.   BIOPHYSICAL JOURNAL

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

(2008) Christopher J Oldfield et al.   BMC GENOMICS

Fluorescence characterization of denatured proteins

(2008) H CHEN et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Quantitative Conformational Analysis of Partially Folded Proteins from Residual Dipolar Couplings: Application to the Molecular Recognition Element of Sendai Virus Nucleoprotein

(2008) Malene Ringkjøbing Jensen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modeling the accessible conformations of the intrinsically unstructured transactivation domain of p53

(2007) David F. Lowry et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

(2007) Peter Tompa et al.   TRENDS IN BIOCHEMICAL SCIENCES