Deficiency of IKKɛ inhibits inflammation and induces cardiac protection in high-fat diet-induced obesity in mice

An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice

(2013) Shannon M Reilly et al.   NATURE MEDICINE

IKKi Deficiency Promotes Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis

(2013) Jia Dai et al.   PLoS One

IKKε Knockout Prevents High Fat Diet Induced Arterial Atherosclerosis and NF-κB Signaling in Mice

(2013) Changchun Cao et al.   PLoS One

IKK biology

(2012) Fei Liu et al.   IMMUNOLOGICAL REVIEWS

IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer

(2012) J Guo et al.   ONCOGENE

T Cell Immunity and Cardiovascular Metabolic Disorders: Does Metabolism Fuel Inflammation?

(2012) Claudio Mauro et al.   Frontiers in Immunology

Beneficial effects of IKKε-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice

(2011) Ludger Scheja et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NF-κB, Inflammation, and Metabolic Disease

(2011) Rebecca G. Baker et al.   Cell Metabolism

IKBKE Protein Activates Akt Independent of Phosphatidylinositol 3-Kinase/PDK1/mTORC2 and the Pleckstrin Homology Domain to Sustain Malignant Transformation

(2011) Jian-Ping Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

I B kinase   (IKK ) regulates the balance between type I and type II interferon responses

(2011) S.-L. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the adaptive immune system in hypertension

(2010) David G Harrison et al.   CURRENT OPINION IN PHARMACOLOGY

IKKɛ: A Bridge between Obesity and Inflammation

(2009) Jerrold M. Olefsky   CELL

The Protein Kinase IKKɛ Regulates Energy Balance in Obese Mice

(2009) Shian-Huey Chiang et al.   CELL

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?

(2008) Tieu-Lan Chau et al.   TRENDS IN BIOCHEMICAL SCIENCES