Journal
MILITARY MEDICINE
Volume 180, Issue 6, Pages E723-E724Publisher
ASSOC MILITARY SURG US
DOI: 10.7205/MILMED-D-14-00485
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Acute hepatotoxicity secondary to infliximab can occur with or without autoimmunity. A growing body of infliximab drug-induced liver injury cases without autoantibody formation is emerging. Nearly all other reported cases occur after at least three doses. This suggests infliximab may have a direct cytotoxic effect on the liver. We report a case of drug-induced liver injury resulting after an initial dose of infliximab.
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