Journal
INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
Volume 21, Issue 1, Pages 41-51Publisher
WILEY-BLACKWELL
DOI: 10.1002/mpr.357
Keywords
major depressive episode; generalized anxiety disorder; post-traumatic stress disorder; WHO Composite International Diagnostic Interview (CIDI); US National Comorbidity Survey Replication Adolescent Supplement (NCS-A)
Categories
Funding
- National Institute of Mental Health (NIMH) [U01-MH60220, R01-MH66627, R01-MH070884, R13-MH066849, R01-MH069864, R01-MH077883]
- National Institute on Drug Abuse (NIDA) [R01-DA016558]
- Substance Abuse and Mental Health Services Administration (SAMHSA)
- Robert Wood Johnson Foundation (RWJF) [044780]
- John W. Alden Trust
- Fogarty International Center of the National Institutes of Health [FIRCA R03-TW006481]
- John D. and Catherine T. MacArthur Foundation
- Pfizer Foundation
- Pan American Health Organization
- Astra Zeneca
- BristolMyersSquibb
- Eli Lilly and Company
- GlaxoSmithKline
- Ortho-McNeil
- Pfizer
- Sanofi-Aventis
- Wyeth
- Analysis Group Inc.
- Bristol-Myers Squibb
- Eli Lilly Company
- EPI-Q
- Johnson & Johnson Pharmaceuticals
- Ortho-McNeil Janssen Scientific Affairs.
- Pfizer Inc.
- Sanofi-Aventis Groupe
- Shire US, Inc.
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Research diagnostic interviews need to discriminate between closely related disorders in order to allow comorbidity among mental disorders to be studied reliably. Yet conventional studies of diagnostic validity generally focus on single disorders and do not examine discriminant validity. The current study examines the validity of fully-structured diagnoses of closely-related distress disorders (generalized anxiety disorder, post-traumatic stress disorder, major depressive episode, and dysthymic disorder) in the lay-administered Composite International Diagnostic Interview Version 3.0 (CIDI) with independent clinical diagnoses based on the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS) in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A). The NCS-A is a national survey of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) among 10,148 adolescents. A probability sub-sample of 347 of these adolescents and their parents were administered blinded follow-up K-SADS interviews. Good concordance [area under the receiver operating characteristic curve (AUC)] was found between diagnoses based on the CIDI and the K-SADS for generalized anxiety disorder (AUC=0.78), post-traumatic stress disorder (AUC=0.79), and major depressive episode/dysthymic disorder (AUC=0.86). Further, the CIDI was able to effectively discriminate among different types of distress disorders in the sub-sample of respondents with any distress disorder. Copyright (C) 2011 John Wiley & Sons, Ltd.
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