☆ 4.1 Article

The influence of interleukin-7 receptor α-chain haplotypes on outcome after allogeneic hematopoietic cell transplantation

INTERNATIONAL JOURNAL OF IMMUNOGENETICS (2014)

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Journal

INTERNATIONAL JOURNAL OF IMMUNOGENETICS
Volume 41, Issue 6, Pages 521-527

Publisher

WILEY
DOI: 10.1111/iji.12158

Keywords

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Categories

Genetics & Heredity Immunology

Funding

  1. Hasselt University
  2. Fonds voor Wetenschappelijk Onderzoek
  3. Belgian Charcot Foundation
  4. University Hospital Rigshospitalet Copenhagen
  5. Dagmar Marshall Foundation
  6. Danish Cancer Society
  7. National Cancer Institute (NCI) [U24-CA076518]
  8. National Heart, Lung and Blood Institute (NHLBI)
  9. National Institute of Allergy and Infectious Diseases (NIAID)
  10. NHLBI [5U10HL069294]
  11. NCI [5U10HL069294]
  12. Health Resources and Services Administration (HRSA/DHHS) [HHSH250201200016C]
  13. Office of Naval Research [N00014-14-1-0028, N00014-13-1-0039]
  14. Actinium Pharmaceuticals
  15. Allos Therapeutics, Inc.
  16. Amgen, Inc.
  17. Ariad
  18. Be the Match Foundation
  19. Blue Cross and Blue Shield Association
  20. Celgene Corporation
  21. Chimerix, Inc.
  22. Fred Hutchinson Cancer Research Center
  23. Fresenius-Biotech North America, Inc.
  24. Gamida Cell Teva Joint Venture Ltd.
  25. Genentech, Inc
  26. Gentium SpA
  27. Genzyme Corporation
  28. GlaxoSmithKline
  29. Health Research, Inc. Roswell Park Cancer Institute
  30. HistoGenetics, Inc.
  31. Incyte Corporation
  32. Jeff Gordon Children's Foundation
  33. Kiadis Pharma
  34. The Leukemia & Lymphoma Society
  35. Medac GmbH
  36. The Medical College of Wisconsin
  37. Merck Co, Inc.
  38. Millennium: The Takeda Oncology Co.
  39. Milliman USA, Inc.
  40. Miltenyi Biotec, Inc.
  41. National Marrow Donor Program
  42. Onyx Pharmaceuticals
  43. Optum Healthcare Solutions, Inc.
  44. Osiris Therapeutics, Inc.
  45. Otsuka America Pharmaceutical, Inc.
  46. Perkin Elmer, Inc.
  47. Remedy Informatics
  48. Sanofi US
  49. Seattle Genetics
  50. Sigma-Tau Pharmaceuticals
  51. Soligenix, Inc.
  52. St. Baldrick's Foundation
  53. StemCyte, A Global Cord Blood Therapeutics Co.
  54. Stemsoft Software, Inc.
  55. Swedish Orphan Biovitrum
  56. Tarix Pharmaceuticals
  57. TerumoBCT
  58. Teva Neuroscience, Inc.
  59. THERAKOS, Inc.
  60. University of Minnesota
  61. University of Utah
  62. Wellpoint, Inc.

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We investigated the influence of IL-7 receptor -chain (IL-7R) gene haplotypes in donors on the outcome of haematopoietic cell transplantation (HCT). Unlike the association between single donor SNPs and HCT outcome found previously, only trends towards association were found here, due to dilution' of SNPs into haplotypes.

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