Mesenchymal stromal cells for cell therapy: besides supporting hematopoiesis

Human Mesenchymal Stem Cells License Adult CD34+ Hemopoietic Progenitor Cells to Differentiate into Regulatory Dendritic Cells through Activation of the Notch Pathway

(2014) Y.-P. Li et al.   JOURNAL OF IMMUNOLOGY

Ex vivo expansion of mesenchymal stromal cells

(2011) Maria Ester Bernardo et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

A comparison between osteogenic differentiation of human unrestricted somatic stem cells and mesenchymal stem cells from bone marrow and adipose tissue

(2011) Abbas Shafiee et al.   BIOTECHNOLOGY LETTERS

Expansion of Adipose Mesenchymal Stromal Cells is Affected by Human Platelet Lysate and Plating Density

(2011) Dominik Cholewa et al.   CELL TRANSPLANTATION

Minimally manipulated whole human umbilical cord is a rich source of clinical-grade human mesenchymal stromal cells expanded in human platelet lysate

(2011) Chiara Capelli et al.   CYTOTHERAPY

Human mesenchymal stromal cells preserve their stem features better when cultured in the Dulbecco's modified Eagle medium

(2011) Laura Pieri et al.   CYTOTHERAPY

Synergistic effects of growth factors and mesenchymal stromal cells for expansion of hematopoietic stem and progenitor cells

(2011) Thomas Walenda et al.   EXPERIMENTAL HEMATOLOGY

Isolation and characterization of mesenchymal stem cells from human umbilical cord blood: Reevaluation of critical factors for successful isolation and high ability to proliferate and differentiate to chondrocytes as compared to mesenchymal stem cells fro

(2011) Xiaohong Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Cell Surface Proteome of Human Mesenchymal Stromal Cells

(2011) Christian Niehage et al.   PLoS One

Mesenchymal Stromal Cells Engage Complement and Complement Receptor Bearing Innate Effector Cells to Modulate Immune Responses

(2011) Guido Moll et al.   PLoS One

Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes

(2011) Felipe Saldanha-Araujo et al.   Stem Cell Research

Serum-deprived human multipotent mesenchymal stromal cells (MSCs) are highly angiogenic

(2011) Adam Oskowitz et al.   Stem Cell Research

Expansion of human bone marrow-derived mesenchymal stromal cells: serum-reduced medium is better than conventional medium

(2010) Katrin Montzka et al.   CYTOTHERAPY

Animal serum-free expansion and differentiation of human mesenchymal stromal cells

(2010) Tino Felka et al.   CYTOTHERAPY

Impact of individual platelet lysates on isolation and growth of human mesenchymal stromal cells

(2010) Patrick Horn et al.   CYTOTHERAPY

Defining the risks of mesenchymal stromal cell therapy

(2010) Darwin J. Prockop et al.   CYTOTHERAPY

Identification of growth and attachment factors for the serum-free isolation and expansion of human mesenchymal stromal cells

(2010) Sunghoon Jung et al.   CYTOTHERAPY

Mesenchymal stromal cells transiently alter the inflammatory milieu post-transplant to delay graft-versus-host disease

(2010) M. E. Christensen et al.   HAEMATOLOGICA

Stromal stem cells from adipose tissue and bone marrow of age-matched female donors display distinct immunophenotypic profiles

(2010) G. Pachón-Peña et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mesenchymal Stem Cells Inhibit Human Th17 Cell Differentiation and Function and Induce a T Regulatory Cell Phenotype

(2010) S. Ghannam et al.   JOURNAL OF IMMUNOLOGY

Neural stem cells differentiation ability of human umbilical cord mesenchymal stromal cells is not altered by cryopreservation

(2010) Hong-Tian Zhang et al.   NEUROSCIENCE LETTERS

Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering

(2010) C. Scotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimization of Culture Conditions for the Expansion of Umbilical Cord-Derived Mesenchymal Stem or Stromal Cell-Like Cells Using Xeno-Free Culture Conditions

(2010) Tim Hatlapatka et al.   TISSUE ENGINEERING PART C-METHODS

Expansion of adipose tissue mesenchymal stromal progenitors in serum-free medium supplemented with virally inactivated allogeneic human platelet lysate

(2010) Daniel Tzu-Bi Shih et al.   TRANSFUSION

A novel serum-free medium for the expansion of human mesenchymal stem cells

(2010) Lucas G Chase et al.   Stem Cell Research & Therapy

Mesenchymal Stromal Cells

(2009) Maria Ester Bernardo et al.   Annals of the New York Academy of Sciences

Paracrine Role for Mesenchymal Stem Cells in Acute Myocardial Infarction

(2009) Zicheng Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2

(2009) G. M. Spaggiari et al.   BLOOD

Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage After Acute Myocardial Infarction

(2009) T. Deuse et al.   CIRCULATION

Human Umbilical Cord Blood-derived Stromal Cells Suppress Xenogeneic Immune Cell Response In Vitro

(2009) Lei Hao et al.   CROATIAN MEDICAL JOURNAL

Cell contact interaction between adipose-derived stromal cells and allo-activated T lymphocytes

(2009) Monique E. Quaedackers et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10

(2009) Seung-Ha Yang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Mesenchymal stem cells suppress B-cell terminal differentiation

(2009) Sadaki Asari et al.   EXPERIMENTAL HEMATOLOGY

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis

(2009) Lianhua Bai et al.   GLIA

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

(2009) Joshua M. Hare et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Preserved Proliferative Capacity and Multipotency of Human Adipose-Derived Stem Cells after Long-Term Cryopreservation

(2009) Koichi Gonda et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Human Alternatives to Fetal Bovine Serum for the Expansion of Mesenchymal Stromal Cells from Bone Marrow

(2009) Karen Bieback et al.   STEM CELLS

Analysis of Different Routes of Administration of Heterologous 5-Azacytidine–Treated Mesenchymal Stem Cells in a Porcine Model of Myocardial Infarction

(2009) I. Moscoso et al.   TRANSPLANTATION PROCEEDINGS

Early improvement in cardiac tissue perfusion due to mesenchymal stem cells

(2008) Karl H. Schuleri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cryoreservation of alginate–fibrin beads involving bone marrow derived mesenchymal stromal cells by vitrification

(2008) Gajadhar Bhakta et al.   BIOMATERIALS

Cell viability, osteoblast differentiation, and gene expression are altered in human osteoblasts from hypertrophic fracture non-unions

(2008) A. Hofmann et al.   BONE

Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I–II clinical trial

(2008) M L MacMillan et al.   BONE MARROW TRANSPLANTATION

Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium

(2008) M von Bonin et al.   BONE MARROW TRANSPLANTATION

Long-term In vitro Expansion Alters the Biology of Adult Mesenchymal Stem Cells

(2008) R. Izadpanah et al.   CANCER RESEARCH

A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1

(2008) Huiming Sheng et al.   CELL RESEARCH

Leukemia inhibitory factor: Role in human mesenchymal stem cells mediated immunosuppression

(2008) Aisha Nasef et al.   CELLULAR IMMUNOLOGY

Co-infusion of donor bone marrow with host mesenchymal stem cells treats GVHD and promotes vascularized skin allograft survival in rats

(2008) Ali Emre Aksu et al.   CLINICAL IMMUNOLOGY

Tissue-engineered bone formation with cryopreserved human bone marrow mesenchymal stem cells

(2008) Guangpeng Liu et al.   CRYOBIOLOGY

Cryopreserved human bone marrow mononuclear cells as a source of mesenchymal stromal cells: application in osteoporosis research

(2008) A. Casado-Díaz et al.   CYTOTHERAPY

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation

(2008) Tatyana B. Prigozhina et al.   EXPERIMENTAL HEMATOLOGY

Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1

(2008) V. L. Battula et al.   HAEMATOLOGICA

The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes

(2008) S. Tabera et al.   HAEMATOLOGICA

Bone Marrow-derived Mesenchymal Stem Cells Decrease Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cells Transplantation

(2008) Y. Tian et al.   IMMUNOLOGICAL INVESTIGATIONS

Autologous bone marrow-derived rat mesenchymal stem cells promote PDX-1 and insulin expression in the islets, alter T cell cytokine pattern and preserve regulatory T cells in the periphery and induce sustained normoglycemia

(2008) Imene Boumaza et al.   JOURNAL OF AUTOIMMUNITY

Histopathological Study of Healing After Allogenic Mesenchymal Stem Cell Delivery in Myocardial Infarction in Dogs

(2008) Deborah C. Vela et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Regeneration of large bone defects in sheep using bone marrow stromal cells

(2008) P. Giannoni et al.   Journal of Tissue Engineering and Regenerative Medicine

The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study

(2008) H Ning et al.   LEUKEMIA

Cotransplantation of haploidentical mesenchymal stem cells to enhance engraftment of hematopoietic stem cells and to reduce the risk of graft failure in two children with severe aplastic anemia

(2008) Baijun Fang et al.   PEDIATRIC TRANSPLANTATION

Mesenchymal Stem Cells Alter Migratory Property of T and Dendritic Cells to Delay the Development of Murine Lethal Acute Graft-Versus-Host Disease

(2008) Hong Li et al.   STEM CELLS

Biodistribution, Long-term Survival, and Safety of Human Adipose Tissue-derived Mesenchymal Stem Cells Transplanted in Nude Mice by High Sensitivity Non-invasive Bioluminescence Imaging

(2008) Marta Vilalta et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal Stromal Cells Expanded in Human Allogenic Cord Blood Serum Display Higher Self-Renewal and Enhanced Osteogenic Potential

(2008) Jooyoung Jung et al.   STEM CELLS AND DEVELOPMENT

Human mesenchymal stem cell transformation is associated with a mesenchymal–epithelial transition

(2007) Daniel Rubio et al.   EXPERIMENTAL CELL RESEARCH

Allogenic mesenchymal stem cell transplantation has a therapeutic effect in acute myocardial infarction in rats

(2007) Yukiko Imanishi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

(2007) Francesco Liotta et al.   STEM CELLS

Mesenchymal Stem Cells Cooperate with Bone Marrow Cells in Therapy of Diabetes

(2007) Veronika S. Urbán et al.   STEM CELLS

Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells

(2007) Zohair Selmani et al.   STEM CELLS