Deregulated transcription factors in leukemia

C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice

(2011) Y.-Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia

(2010) R. Kanezaki et al.   BLOOD

PML/RARα Targets Promoter Regions Containing PU.1 Consensus and RARE Half Sites in Acute Promyelocytic Leukemia

(2010) Kankan Wang et al.   CANCER CELL

A Higher-Order Complex Containing AF4 and ENL Family Proteins with P-TEFb Facilitates Oncogenic and Physiologic MLL-Dependent Transcription

(2010) Akihiko Yokoyama et al.   CANCER CELL

PML-RARα/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia

(2010) Joost H.A. Martens et al.   CANCER CELL

PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

(2010) Yukiko Aikawa et al.   NATURE MEDICINE

Hematopoietic Stem Cell Expansion Precedes the Generation of Committed Myeloid Leukemia-Initiating Cells in C/EBPα Mutant AML

(2009) Oxana Bereshchenko et al.   CANCER CELL

TEL-AML1 Corrupts Hematopoietic Stem Cells to Persist in the Bone Marrow and Initiate Leukemia

(2009) Jeffrey W. Schindler et al.   Cell Stem Cell

LPXN, a member of the paxillin superfamily, is fused toRUNX1in an acute myeloid leukemia patient with a t(11;21)(q12;q22) translocation

(2009) Hai-Ping Dai et al.   GENES CHROMOSOMES & CANCER

Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes

(2008) Akihiko Yokoyama et al.   CANCER CELL

Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells

(2008) Peggy Kirstetter et al.   CANCER CELL

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

PML Activates Transcription by Protecting HIPK2 and p300 from SCFFbx3-Mediated Degradation

(2008) Y. Shima et al.   MOLECULAR AND CELLULAR BIOLOGY

Initiating and Cancer-Propagating Cells in TEL-AML1-Associated Childhood Leukemia

(2008) D. Hong et al.   SCIENCE