Phosphatidylinositol 4-kinase III beta is the target of oxoglaucine and pachypodol (Ro 09-0179) for their anti-poliovirus activities, and is located at upstream of the target step of brefeldin A

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

(2015) Jeroen R.P.M. Strating et al.   Cell Reports

Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

(2015) Michael B Schulte et al.   eLife

Rhinovirus Uses a Phosphatidylinositol 4-Phosphate/Cholesterol Counter-Current for the Formation of Replication Compartments at the ER-Golgi Interface

(2014) Pascal S. Roulin et al.   Cell Host & Microbe

Phosphatidylinositol-4 kinase III beta and oxysterol-binding protein accumulate unesterified cholesterol on poliovirus-induced membrane structure

(2014) Minetaro Arita   MICROBIOLOGY AND IMMUNOLOGY

Inhibition of Enterovirus 71 Replication by 7-Hydroxyflavone and Diisopropyl-Flavon7-yl Phosphate

(2014) Jianmin Wang et al.   PLoS One

Anti-Enterovirus 71 Effects of Chrysin and Its Phosphate Ester

(2014) Jianmin Wang et al.   PLoS One

Generation of Unique Poliovirus RNA Replication Organelles

(2014) A. L. Richards et al.   mBio

Phosphatidylinositol 4-Kinase III Beta Is Essential for Replication of Human Rhinovirus and Its Inhibition Causes a Lethal PhenotypeIn Vivo

(2013) Catherine Spickler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Novel, Broad-Spectrum Inhibitor of Enterovirus Replication That Targets Host Cell Factor Phosphatidylinositol 4-Kinase IIIβ

(2013) Hilde M. van der Schaar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Oxysterol-Binding Protein Family I Is the Target of Minor Enviroxime-Like Compounds

(2013) M. Arita et al.   JOURNAL OF VIROLOGY

Targeting Plasmodium PI(4)K to eliminate malaria

(2013) Case W. McNamara et al.   NATURE

Increased Long Chain acyl-Coa Synthetase Activity and Fatty Acid Import Is Linked to Membrane Synthesis for Development of Picornavirus Replication Organelles

(2013) Jules A. Nchoutmboube et al.   PLoS Pathogens

Anti-Hepatitis C Virus Activity and Toxicity of Type III Phosphatidylinositol-4-Kinase Beta Inhibitors

(2012) M. J. LaMarche et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication

(2012) Leen Delang et al.   BIOCHEMICAL PHARMACOLOGY

Fisetin and rutin as 3C protease inhibitors of enterovirus A71

(2012) Ying-Ju Lin et al.   JOURNAL OF VIROLOGICAL METHODS

Valosin-Containing Protein (VCP/p97) Is Required for Poliovirus Replication and Is Involved in Cellular Protein Secretion Pathway in Poliovirus Infection

(2012) M. Arita et al.   JOURNAL OF VIROLOGY

An RNA virus hijacks an incognito function of a DNA repair enzyme

(2012) R. Virgen-Slane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Picornavirus Modification of a Host mRNA Decay Protein

(2012) J. M. Rozovics et al.   mBio

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

(2011) Jun Sasaki et al.   EMBO JOURNAL

Inhibition of enterovirus 71 replication by chrysosplenetin and penduletin

(2011) Qin-Chang Zhu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Complex Dynamic Development of Poliovirus Membranous Replication Complexes

(2011) G. A. Belov et al.   JOURNAL OF VIROLOGY

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Poliovirus replication requires the N-terminus but not the catalytic Sec7 domain of ArfGEF GBF1

(2010) George A. Belov et al.   CELLULAR MICROBIOLOGY

Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L.

(2010) Rocky Graziose et al.   JOURNAL OF ETHNOPHARMACOLOGY

A bifunctional anti-enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection

(2010) M. Arita et al.   JOURNAL OF GENERAL VIROLOGY

Phosphatidylinositol 4-Kinase III Beta Is a Target of Enviroxime-Like Compounds for Antipoliovirus Activity

(2010) M. Arita et al.   JOURNAL OF VIROLOGY

Avoiding drug-resistance development by novel approach of combining anti-enteroviral substances against coxsackievirus B1 infection in mice

(2009) Ralitsa Vassileva-Pencheva et al.   ANTIVIRAL RESEARCH

Toll-like receptor-mediated anti-inflammatory action of glaucine and oxoglaucine

(2009) Mimi Remichkova et al.   FITOTERAPIA

Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime

(2009) M. Arita et al.   JOURNAL OF GENERAL VIROLOGY

Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity

(2008) M. Arita et al.   JOURNAL OF GENERAL VIROLOGY