Journal
MICROBIAL DRUG RESISTANCE
Volume 21, Issue 1, Pages 97-101Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/mdr.2014.0056
Keywords
-
Funding
- MURST ex 60% (Ministero dell'Istruzione, dell'Universita e della Ricerca)
Ask authors/readers for more resources
In this study 114 extensively drug-resistant Acinetobacter baumannii clinical isolates were characterized. The strains were collected at L'Aquila Hospital after the earthquake in L'Aquila city (central Italy) on the 6th of April 2009. The genes bla(OXA-23) and bla(OXA-51) were detected in all clinical isolates analyzed, whereas bla(TEM-1) allele was detected in 56/114 isolates. The bla(OXA-23) gene is located downstream the ISAba region and is under control of a strong promoter. On 42/80 A. baumannii the presence of two class 1 integrons was ascertained on chromosomal DNA. Variable regions show different gene array: (1) aadB and aadA2, (2) aacA4, aac(6 ')-Ib-cr, and aadA1. Macrorestriction analysis using ApaI restriction endonuclease identifies three clusters (A, B, and C) according to pulsed-field gel electrophoresis profiles. All isolates analyzed belong to the clone A. baumannii sequence type 2.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available