Magnitude of effects in clinical trials published in high-impact general medical journals

Composite Outcomes Can Distort the Nature and Magnitude of Treatment Benefits in Clinical Trials

(2013) Ignacio Ferreira-Gonzalez   ANNALS OF INTERNAL MEDICINE

Stopping Randomized Trials Early for Benefit and Estimation of Treatment EffectsSystematic Review and Meta-regression Analysis

(2010) Dirk Bassler   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Conflicts of Interest at Medical Journals: The Influence of Industry-Supported Randomised Trials on Journal Impact Factors and Revenue – Cohort Study

(2010) Andreas Lundh et al.   PLOS MEDICINE

Citations to trials of nicotine replacement therapy were biased toward positive results and high-impact-factor journals

(2009) Jean-François Etter et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Variation in results from randomized, controlled trials: stochastic or systematic?

(2009) Daniel Jane-wit et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Undue reliance on I 2 in assessing heterogeneity may mislead

(2008) Gerta Rücker et al.   BMC Medical Research Methodology

Why Most Discovered True Associations Are Inflated

(2008) John P. A. Ioannidis   EPIDEMIOLOGY

Early stopping of randomized clinical trials for overt efficacy is problematic

(2008) Dirk Bassler et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy

(2008) Erick H. Turner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias

(2008) Kerry Dwan et al.   PLoS One

Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study

(2008) Lesley Wood et al.   BMJ-British Medical Journal

Why Current Publication Practices May Distort Science

(2008) Neal S Young et al.   PLOS MEDICINE