Article
Parasitology
Aisha Khan, Rawan Sajid, Shaista Gul, Ashiq Hussain, Mohammad Tahir Zehri, Shumaila Naz, Sami Simsek, Shahid Waseem, Muhammad Sohail Afzal, Syed Kamran Ul Hassan Naqvi, Muhammad Qasim, Haroon Ahmed
Summary: Cutaneous Leishmaniasis (CL) is a growing public health issue in Baluchistan Province, Pakistan, with a higher prevalence rate in males aged 0-9 years. Most lesions were found on the hands, and atypical presentations such as lupus erythematosus were observed. More epidemiological studies and health education campaigns are recommended to raise awareness and establish control strategies.
Review
Dermatology
Christopher Iriarte, Dustin H. Marks
Summary: The clinical manifestations of parasitic diseases often receive limited attention, but with increased travel and transportation, more individuals are acquiring cutaneous infections while traveling abroad. This review highlights the cutaneous manifestations of schistosomiasis, focusing on international travelers with atypical presentations.
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2023)
Article
Pharmacology & Pharmacy
Atousa Hakamifard, Reza Radmehr, Fatemeh Sokhanvari, Fatemeh Sherkat, Amirali Hariri, Jaleh Varshosaz, Zabihollah Shahmoradi, Awat Feizi, Bahareh Abtahi-Naeini, Mahsa Pourmahdi-Boroujeni
Summary: This study aimed to investigate the effects of topical liposomal clarithromycin in combination with meglumine antimoniate on cutaneous leishmaniasis lesions. The results showed that the combination treatment significantly reduced the size of the lesions and had no significant adverse effects.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Infectious Diseases
Corentine Vanlier, Liliane Marot, Eva Laranaga, Philippe D'abadie, Jean-Cyr Yombi, Halil Yildiz, Marie Baeck
Summary: The diagnosis of cutaneous leishmaniasis can be challenging due to its diverse clinical presentations, misleading appearance, and long incubation period. Treatment choice depends on the species of Leishmania, with liposomal amphotericin B showing positive responses in some cases.
Article
Infectious Diseases
Shagufta Rather, Mashkoor Wani, Faizan Younus Shah, Safia Bashir, Atiya Yaseen, Firdous Ahmad Giri, Rajesh Sharma, Sumaya Zeerak, Yasmeen Jabeen, Iffat Hassan, Devraj Dogra, Ruby Rishi
Summary: This study describes the clinical-epidemiological profile, therapeutic characteristics, and outcomes of cutaneous leishmaniasis patients in Jammu and Kashmir, suggesting the region as a new focus of endemicity for the disease. Results show that 84.23% of cases achieved complete cure, with single lesions more likely to respond to treatment. The escalating trend of the disease in the region calls for appropriate measures to contain its spread.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Yingze Zhao, Ping Tie, Yongfei Bai, Liping Wang, Yuhua Zheng, Jiaojiao Zhang, Xiao Qi, Canjun Zheng, Xiao-nong Zhou
Summary: This report provides an overview of the epidemiology of visceral leishmaniasis (VL) and the recent reemergence of the disease in Shanxi Province, China. It emphasizes the need for public health measures such as health education, improved diagnostics, epidemiological investigation capacity, surveillance, and evidence-based preventive measures in the province.
Article
Public, Environmental & Occupational Health
Yasser Alraey
Summary: This study is the first large-scale investigation into the seasonality, spatial distribution, and demographics of cutaneous leishmaniasis (CL) in Asir province. It reveals that Saudi male citizens and children under 13 years old are at higher risk of CL infection, with most cases reported in the face during winter and autumn seasons. Geographically, the governates of Abha, Sarat-Abidah, and Khamis-Mushait have the highest prevalence of CL, with a noted geographical expansion of CL over the past ten years.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Mohammed Badedi, Hussain Darraj, Awaji Qasem Alnami, Ali Makrami, Mohamed Salih Mahfouz, Khalid Alhazmi, Nahid Mahmoud, Halimh Mosa
Summary: Deaths due to COVID-19 in hospitalized patients in Jazan Region, Saudi Arabia were more common in males and individuals over 65 years old. Comorbidities such as diabetes, hypertension, obesity, heart disease, and chronic kidney disease were prevalent among deceased patients. Advanced age, smoking, and respiratory failure were significant predictors of mortality during the early stay in hospitals.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Qian Lin, Bin Deng, Jia Rui, Song-Bai Guo, Qingqing Hu, Qiuping Chen, Chi Tang, Lina Zhou, Zeyu Zhao, Shengnan Lin, Yuanzhao Zhu, Meng Yang, Yao Wang, Jingwen Xu, Xingchun Liu, Tianlong Yang, Peihua Li, Zhuoyang Li, Li Luo, Weikang Liu, Chan Liu, Jiefeng Huang, Min Yao, Mengni Nong, Liping Nong, Jinglan Wu, Na Luo, Shihai Chen, Roger Frutos, Shixiong Yang, Qun Li, Jing-An Cui, Tianmu Chen
Summary: This study aimed to evaluate the epidemiologic characteristics and transmissibility of HIV in Nanning City, China. Results showed high-risk areas were mainly in suburbs, and high-risk groups were older individuals with lower income and education levels. The study also found a decline in HIV transmissibility over the past 20 years, suggesting significant improvement in prevention and treatment measures in Nanning City.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Oncology
Zheng Yang, Daoqing Gong, Fei Huang, Yi Sun, Qinming Hu
Summary: This study aims to investigate the epidemiological characteristics of HIV-associated CTCL and establish a nomogram for predicting patient survival. The study found that the incidence of HIV-associated CTCL has been increasing and identified clinical characteristics and prognostic factors that could contribute to patient survival.
FRONTIERS IN ONCOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Francisca Miriane de Araujo Batista, Roniele Araujo de Sousa, Bruno Guedes Alcoforado Aguiar, Andressa Barros Ibiapina, Layana Pacheco de Araujo Albuquerque, Vagner Jose Mendonca, Carlos Henrique Nery Costa
Summary: The study analyzed the time trend of visceral leishmaniasis (VL) cases in the state of Piaui, Brazil, and found a cyclical nature of the disease with significant changes in incidence in certain regions.
CADERNOS DE SAUDE PUBLICA
(2021)
Article
Dermatology
Rodolfo David Palacios-Diaz, Antonio Sahuquillo-Torralba, Vicenc Rocamora-Duran, Blanca de Unamuno-Bustos, Miguel Salavert-Lleti, Sergio Santos-Alarcon, Adriana Quintero, Joan Garcias-Ladaria, Aina Vila-Payeras, Alvaro Martinez-Domenech, Almudena Mateu-Puchades, Cristina Nadal-Llado, Rafael Botella-Estrada
Summary: This study aimed to describe the characteristics of patients with cutaneous or mucocutaneous leishmaniasis who were receiving biological therapy. The results showed that leishmaniasis presented more frequently as a plaque with ulceration and required more intralesional injections in patients treated with TNF-a inhibitors. There was no systemic involvement in these patients. The study concluded that biologic therapy does not interfere with the treatment of CL or MCL.
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT
(2023)
Article
Immunology
Tirza Gabrielle Ramos de Mesquita, Jose do Espirito Santo Junior, Luan Diego Oliveira da Silva, George Allan Villarouco Silva, Felipe Jules de Araujo, Suzana Kanawati Pinheiro, Herllon Karllos Athaydes Kerr, Lener Santos da Silva, Luciane Macedo de Souza, Samir Assad de Almeida, Krys Layane Guimaraes Duarte Queiroz, Josue Lacerda de Souza, Cilana Chagas da Silva, Hector David Graterol Sequera, Mara Lucia Gomes de Souza, Anderson Nogueira Barbosa, Gemilson Soares Pontes, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy
Summary: The immunopathology associated with Leishmaniasis is a consequence of inflammation that may lead to different clinical manifestations depending on host-immune response type, with various pathways influencing disease severity. Comparing immune profiles in patients with cutaneous leishmaniasis caused by L. guyanensis and healthy individuals helps identify specific immune factors related to disease development progression. Multiple biomarker pairs showed high correlation, with cytokines IL-17 and IL-1 beta exhibiting the most positive pair correlation among patients. Prediction of disease progression in Lg-infected individuals may be associated with specific cytokines.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Parasitology
Zahra Nasiri, Mohsen Kalantari, Jalal Mohammadi, Salman Daliri, Davood Mehrabani, Kourosh Azizi
Summary: This study reviewed the epidemiology, reservoirs, vectors, and climatic factors of cutaneous leishmaniasis (CL) in Iran. The prevalence of CL was found to be high in western Iran and has spread to the central and southern regions in recent years. Certain regions in southern Iran are notable hotspots for CL due to the presence of potential rodent hosts. Molecular identification using genomic diagnosis revealed heterogeneity in leishmaniasis across different parts of the country.
Article
Dermatology
Orquidea L. Rodriguez, Dennis A. Lugo, Maira Cabrera, Martin A. Sanchez, Olga Zerpa, Felix J. Tapia
Summary: This study investigated circulating innate lymphoid cells (ILCs) in different types of cutaneous leishmaniasis patients, revealing variations in the proportions of ILC1, ILC2, and ILC3 among them. ILC1 and ILC3 were associated with disease control and inflammation regulation, while ILC2 was linked to the tolerogenic state of the patients.
EXPERIMENTAL DERMATOLOGY
(2021)
