Article
Radiology, Nuclear Medicine & Medical Imaging
Shi-hai Zhao, Wei-feng Guo, Zhi-feng Yao, Shan Yang, Hong Yun, Yin-yin Chen, Tong-tong Han, Xiao-yue Zhou, Cai-xia Fu, Meng-su Zeng, Chen-guang Li, Cui-zhen Pan, Hang Jin
Summary: In this study, a fully automated pixel-wise post-processing framework was used to evaluate quantitative cardiovascular magnetic resonance myocardial perfusion imaging (CMR-MPI). The study aimed to assess the additional value of coronary magnetic resonance angiography (CMRA) in the diagnostic performance of fully automated pixel-wise quantitative CMR-MPI for detecting hemodynamically significant coronary artery disease (CAD). The results showed that the fully automated pixel-wise quantitative CMR-MPI can accurately detect hemodynamically significant CAD, but the integration of CMRA did not provide significantly additive value.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Gemma A. Figtree, Philip D. Adamson, Charalambos Antoniades, Roger S. Blumenthal, Michael Blaha, Matthew Budoff, David S. Celermajer, Mark Y. Chan, Clara K. Chow, Damini Dey, Girish Dwivedi, Nicola Giannotti, Stuart M. Grieve, Christian Hamilton-Craig, Bronwyn A. Kingwell, Jason C. Kovacic, James K. Min, David E. Newby, Sanjay Patel, Karlheinz Peter, Peter J. Psaltis, Stephen T. Vernon, Dennis T. Wong, Stephen J. Nicholls
Summary: Coronary artery disease (CAD) is the leading cause of adult mortality globally. Improvements in imaging techniques have provided a better understanding of different phenotypes of coronary atherosclerosis, which are associated with different risks for acute ischemic events. Noninvasive coronary imaging techniques have the potential to accelerate cardiovascular drug development and reduce costs and timelines.
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Lin, Liang Wang, Xiao-Na Zhang, Xiao Li, Jian Wang, Zhu-Jun Shen, Wei Chen, Zheng-Yu Jin, Yi-Ning Wang
Summary: This study evaluated the diagnostic performance of 1.5-T non-contrast MR coronary angiography for detecting coronary artery disease. The results showed that the combined use of whole-heart and volume-targeted imaging in MRCA can efficiently diagnose significant coronary stenosis with high sensitivity and moderate specificity.
EUROPEAN RADIOLOGY
(2021)
Review
Medicine, General & Internal
Chiara Rovera, Claudio Moretti, Francesca Bisanti, Giulia De Zan, Marco Guglielmo
Summary: Myocardial bridging is a congenital coronary anomaly where a segment of a coronary artery deviates from its normal route and passes through the myocardium. The use of cardiac computed tomography angiography has greatly improved the ability to identify myocardial bridging. Furthermore, new post-processing methods have emerged to extract functional insights from anatomical evaluations. Although myocardial bridging is generally considered benign, there is increasing evidence that certain characteristics may be associated with cardiovascular morbidity.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Muhummad Sohaib Nazir, Aurelien Bustin, Reza Hajhosseiny, Momina Yazdani, Matthew Ryan, Vittoria Vergani, Radhouene Neji, Karl P. Kunze, Edward Nicol, Pier Giorgio Masci, Divaka Perera, Sven Plein, Amedeo Chiribiri, Rene Botnar, Claudia Prieto
Summary: This study demonstrates the good diagnostic accuracy of high-resolution coronary cardiovascular magnetic resonance angiography (CCMRA) for detecting coronary artery disease (CAD). The sensitivity and negative predictive value are high, while the positive predictive value is moderate.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2022)
Review
Multidisciplinary Sciences
Aryan Zahergivar, Madison Kocher, Jeffrey Waltz, Ismail Kabakus, Jordan Chamberlin, Selcuk Akkaya, Ali M. Agha, U. Joseph Schoepf, Jeremy R. Burt
Summary: The non-contrast MRI coronary angiography showed high sensitivity and specificity in screening patients with suspected CAD, with results consistent across per-patient, per-vessel, and per-segment assessments.
Review
Medicine, General & Internal
Anna Baritussio, Alessandra Scatteia, Santo Dellegrottaglie, Chiara Bucciarelli-Ducci
Summary: Cardiovascular magnetic resonance is a valuable imaging technique with clear applications in managing patients with coronary artery disease, from diagnosis to prognosis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Andrew E. Arai, Jeanette Schulz-Menger, Dipan J. Shah, Yuchi Han, W. Patricia Bandettini, Arun Abraham, Pamela K. Woodard, Joseph B. Selvanayagam, Christian Hamilton-Craig, Ru-San Tan, James Carr, Lynette Teo, Christopher M. Kramer, Bernd J. Wintersperger, Mukesh G. Harisinghani, Scott D. Flamm, Matthias G. Friedrich, Igor Klem, Subha Raman, Daniel Haverstock, Zheyu Liu, Guenther Brueggenwerth, Marta Santiuste, Daniel S. Berman, Dudley J. Pennell
Summary: The study demonstrates that vasodilator stress perfusion cardiovascular magnetic resonance (CMR) performed with gadobutrol has superior diagnostic accuracy for the diagnosis and exclusion of significant coronary artery disease (CAD) compared to gated single-photon emission computed tomography (SPECT).
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Reza Hajhosseiny, Imran Rashid, Aurelien Bustin, Camila Munoz, Gastao Cruz, Muhummad Sohaib Nazir, Karine Grigoryan, Tevfik F. Ismail, Rebecca Preston, Radhouene Neji, Karl Kunze, Reza Razavi, Amedeo Chiribiri, Pier Giorgio Masci, Ronak Rajani, Claudia Prieto, Rene M. Botnar
Summary: The study demonstrates that coronary CMRA has high diagnostic image quality and accuracy compared to coronary CTA, showing its potential as a robust and safe non-invasive alternative for excluding significant disease in low to intermediate risk CAD patients.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2021)
Article
Nutrition & Dietetics
Yukihiko Momiyama, Yoshimi Kishimoto, Emi Saita, Masayuki Aoyama, Reiko Ohmori, Kazuo Kondo
Summary: Several cohort studies have shown that the Japanese diet is associated with reduced cardiovascular disease mortality, but the results are inconsistent and most studies were conducted in the 1990s. To further investigate this association, this study examined 802 patients undergoing coronary angiography and found that the intake of fish, soy products, vegetables, seaweed, fruits, and green tea was lower in patients with coronary artery disease (CAD), especially those with myocardial infarction (MI), compared to those without CAD. The Japanese diet score was significantly lower in CAD patients and the proportion of CAD and MI decreased with higher Japanese diet scores.
Article
Cardiac & Cardiovascular Systems
Christopher J. Rush, Colin Berry, Keith G. Oldroyd, J. Paul Rocchiccioli, M. Mitchell Lindsay, Rhian M. Touyz, Clare L. Murphy, Thomas J. Ford, Novalia Sidik, Margaret B. McEntegart, Ninian N. Lang, Pardeep S. Jhund, Ross T. Campbell, John J. V. McMurray, Mark C. Petrie
Summary: In this cohort study, it was found that 91% of patients with HFpEF had evidence of epicardial CAD, CMD, or both. Among those without obstructive CAD, 81% had CMD. Patients with obstructive CAD experienced more adverse events during follow-up.
Article
Radiology, Nuclear Medicine & Medical Imaging
Theo Pezel, Philippe Garot, Marine Kinnel, Thierry Unterseeh, Thomas Hovasse, Stephane Champagne, Solenn Toupin, Francesca Sanguineti, Jerome Garot
Summary: Silent ischaemia and unrecognized MI were found to be independent predictors of major adverse cardiovascular events (MACE) in asymptomatic individuals with multiple risk factors and without known coronary artery disease (CAD), indicating their good long-term prognostic value. These stress CMR parameters have incremental long-term prognostic value over traditional risk factors for predicting MACE.
EUROPEAN RADIOLOGY
(2021)
Article
Multidisciplinary Sciences
Stefan Herz, Maria R. Stefanescu, David Lohr, Patrick Vogel, Aleksander Kosmala, Maxim Terekhov, Andreas M. Weng, Jan-Peter Grunz, Thorsten A. Bley, Laura M. Schreiber
Summary: This study investigates the effects of B-1-shimming and RF parallel transmission on the visualization and quantification of coronary artery stenosis using 7 Tesla MRI. The results demonstrate that B-1-shimming and pTX significantly improve image homogeneity and provide more accurate MR image analysis.
Article
Cardiac & Cardiovascular Systems
Anda Bularga, John Hung, Marwa Daghem, Stacey Stewart, Caelan Taggart, Ryan Wereski, Trisha Singh, Mohammed N. Meah, Takeshi Fujisawa, Amy V. Ferry, Justin Chiong, William S. Jenkins, Fiona E. Strachan, Scott Semple, Edwin J. R. van Beek, Michelle Williams, Damini Dey, Chris Tuck, Andrew H. Baker, David E. Newby, Marc R. Dweck, Nicholas L. Mills, Andrew R. Chapman
Summary: Coronary and cardiac imaging of patients with type 2 myocardial infarction identified coronary artery disease in two-thirds of patients and left ventricular systolic dysfunction in one-third of patients. Unrecognized and untreated coronary or cardiac disease is seen in most patients with type 2 myocardial infarction, presenting opportunities for initiation of evidence-based treatments with major potential to improve clinical outcomes.
Review
Cardiac & Cardiovascular Systems
Weiren Lau, Phong Teck Lee, Choong Hou Koh
Summary: Coronary artery anomalies (CAAs) are a wide range of anatomical abnormalities with varied clinical presentations. We report a case of an anomalous right coronary artery arising from the left aortic sinus with an interarterial course, which can be potentially life-threatening and lead to ischemia and sudden cardiac death. CAAs are increasingly being detected in adults as incidental findings during cardiac evaluation due to the use of invasive and noninvasive cardiac imaging for possible coronary artery disease (CAD). The prognostic significance of CAAs in these patients is still unclear. Appropriate anatomical and functional imaging should be performed for risk stratification in patients with AAOCA. Individualized management approaches should consider symptoms, age, sporting activities, and the presence of high-risk anatomical features and physiologic consequences detected on multimodality imaging or other functional cardiac investigations. This comprehensive review aims to summarize current data and propose a clinical management algorithm for clinicians facing the challenge of managing such conditions. (Curr Probl Cardiol 2023;48:101935.)
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ward Eertmans, Peter Kayaert, Johan Bennett, Claudiu Ungureanu, Yoann Bataille, Georges Saad, Steven Haine, Patrick Coussement, Bruno Pereira, Pierfrancesco Agostoni, Luc Janssens, Bert Vandeloo, Patrick Marechal, Kristoff Cornelis, Quentin de Hemptinne, Adel Aminian, Francis Stammen, Stephane Carlier, Patrick Timmermans, Steven Vercauteren, Jeroen Sonck, Frederic De Vroey, Benny Drieghe, Keir McCutcheon, Benjamin Scott, Laurent Davin, Chadi Gafari, Jo Dens
Summary: The Belgian Working Group on Chronic Total Occlusions (BWGCTO) was established in 2016 to study the evolution of CTO-PCI landscape in Belgium and Luxembourg. Over a four-year period, high-volume centers treated more complex CTO lesions without significant differences in success rates, with the most common strategy being antegrade wire escalation. Despite variable operator experience levels, successful treatment of CTOs with relatively low complications was achieved, highlighting the importance of operator skill in contemporary techniques for successful treatment of complex CTOs.
Article
Cardiac & Cardiovascular Systems
Peter Kayaert, Mathieu Coeman, Benny Drieghe, Johan Bennett, Keir McCutcheon, Jo Dens, Claudiu Ungureanu, Carlo Zivelonghi, Pierfrancesco Agostoni, Yoann Bataille, Quentin de Hemptinne, Sofie Gevaert, Michel De Pauw, Steven Haine
Summary: The study demonstrated that iFR assessment can optimize PCI results in CTO patients, with 70% experiencing immediate relief of myocardial ischemia post-PCI. Manual iFR pullback proved helpful in guiding further optimization of PCI results in the remaining 30% of cases.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Pierfrancesco Agostoni, Benjamin Scott, Simone Budassi, Stefan Verheye, Carl Convens, Paul Vermeersch, Carlo Zivelonghi
Summary: The study aimed to assess the feasibility of the Minimalistic Hybrid Approach (MHA) algorithm for chronic total occlusion (CTO) percutaneous coronary intervention (PCI). The results showed that the MHA algorithm was successful in almost every CTO lesion when applied by operators experienced with the wrist approach and hybrid techniques.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Adriaan Wilgenhof, Carlo Zivelonghi, Stefan Verheye, Paul Vermeersch, Benjamin Scott, Carl Convens, Leo Timmers, Geert Leenders, Jan Peter Van Kuijk, Pieter Stella, Pierfrancesco Agostoni
Summary: The study found that a favorable C-shaped anatomy allows for easier implantation of the CS Reducer, reducing procedural and fluoroscopic time. The presence of valves or bifurcations along the CS course does not affect procedural timings.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
M. J. M. Silvis, M. Dekker, C. Zivelonghi, P. Agostoni, P. R. Stella, P. A. Doevendans, D. P. V. de Kleijn, J. P. van Kuijk, G. E. Leenders, L. Timmers
Summary: Refractory angina is a significant healthcare issue affecting millions of patients worldwide. The Coronary Sinus Reducer (CSR) has shown to be a safe and effective option for most patients, with successful implantation in 99% of cases. However, future studies should focus on identifying patients who may not benefit from this therapy.
NETHERLANDS HEART JOURNAL
(2021)
Review
Cardiac & Cardiovascular Systems
Giovanni Maria Vescovo, Carlo Zivelonghi, Michele Bellamoli, Paul Vermeersch, Stefan Verheye, Pierfrancesco Agostoni
Summary: Coronary Sinus Reducer implantation has a rationale in patients with chronic total occlusion as an alternative or additional therapy to myocardial revascularization.
CURRENT CARDIOLOGY REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Nicole D. van Hemert, Rik Rozemeijer, Michiel Voskuil, Mera Stein, Peter Frambach, Saskia Z. Rittersma, Adriaan O. Kraaijeveld, Geert E. H. Leenders, Pim van der Harst, Pierfrancesco Agostoni, Pieter R. Stella
Summary: This analysis compared the efficacy of permanent polymer and polymer-free drug-eluting stents in diabetics, finding no significant difference in the primary endpoint between the two types of stents, although the PP-ZES group had higher rates of net adverse clinical events.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Thomas A. Meijers, Adel Aminian, Marleen van Wely, Koen Teeuwen, Thomas Schmitz, Maurits T. Dirksen, Sudhir Rathore, Rene J. van der Schaaf, Paul Knaapen, Joseph Pens, Juan F. Iglesias, Pierfrancesco Agostoni, Vincent Roolvink, Renicus S. Hermanides, Niels van Royen, Maarten A. H. van Leeuwen
Summary: In patients with complex coronary lesions requiring large-bore access, transradial PCI was associated with significantly lower clinically relevant access-site bleeding or vascular complications compared to transfemoral PCI, without affecting procedural success.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Giuseppe De Luca, Niels Debel, Miha Cercek, Lisette Okkels Jensen, Marija Vavlukis, Lucian Calmac, Tom Johnson, Gerard Rourai Ferrer, Vladimir Ganyukov, Wojtek Wojakowski, Tim Kinnaird, Clemens von Birgelen, Yves Cottin, Alexander IJsselmuiden, Bernardo Tuccillo, Francesco Versaci, Kees-Jan Royaards, Jurrien ten Berg, Mika Laine, Maurits Dirksen, Massimo Siviglia, Gianni Casella, Petr Kala, Jose Luis Diez Gil, Adrian Banning, Victor Becerra, Ciro De Simone, Andrea Santucci, Xavier Carrillo, Alessandra Scoccia, Giovanni Amoroso, Arnoud Wj van't Hof, Tomas Kovarnik, Grigorios Tsigkas, Julinda Mehilli, Gabriele Gabrielli, Xacobe Flores Rios, Nikola Bakraceski, Sebastien Levesque, Giuseppe Cirrincione, Vincenzo Guiducci, Michal Kidawa, Leonardo Spedicato, Lucia Marinucci, Peter Ludman, Filippo Zilio, Gennaro Galasso, Enrico Fabris, Maurizio Menichelli, Arturo Garcia-Touchard, Stephane Manzo, Gianluca Caiazzo, Jose Moreu, Juan Sanchis Fores, Luca Donazzan, Luigi Vignali, Rui Teles, Edouard Benit, Pierfrancesco Agostoni, Francisco Bosa Ojeda, Heidi Lehtola, Santiago Camacho-Freiere, Adriaan Kraaijeveld, Ylitalo Antti, Marco Boccalatte, Pierre Deharo, Inigo Lozano Martinez-Luengas, Bruno Scheller, Efthymia Varytimiadi, Raul Moreno, Giuseppe Uccello, Benjamin Faurie, Alejandro Gutierrez Barrios, Marek Milewski, Ewout Bruwiere, Pieter Smits, Bor Wilbert, Fortunato Scotto Di Uccio, Guido Parodi, Elvin Kedhi, Monica Verdoia
Summary: The study reveals that among STEMI patients undergoing PPCI, those who are SARS-CoV-2 positive have a higher mortality rate, higher incidence of in-stent thrombosis, and are more likely to have culprit lesions in the right coronary artery compared to SARS-CoV-2 negative patients.
Article
Cardiac & Cardiovascular Systems
Giovanni M. Vescovo, Carlo Zivelonghi, Pierfrancesco Agostoni, Mirthe Dekker, Max Silvis, Geert Leenders, Jan Peter van Kuijk, Leo Timmers, Pieter Stella, Shmuel Banai, Stefan Verheye
Summary: This study aimed to explore the impact of diabetes mellitus on the response to Coronary Sinus Reducer (CSR) implantation in patients with refractory angina. The results showed that CSR implantation was equally effective in improving angina symptoms among patients with refractory angina and diabetes mellitus compared to patients without diabetes mellitus.
Article
Surgery
David J. Liesker, Douwe J. Mulder, Marjan Wouthuyzen-Bakker, Niek H. J. Prakken, Riemer H. J. A. Slart, Clark J. Zeebregts, Ben R. Saleem
Summary: This study evaluates the clinical characteristics, diagnostics, treatment and outcome of patients with a mycotic abdominal aortic aneurysm and shows a large variation in presentation and treatment of this rare disease.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Medicine, General & Internal
Gert J. H. Snel, Sharon Poort, Birgitta K. Velthuis, Vincent M. van Deursen, Christopher T. Nguyen, David Sosnovik, Rudi A. J. O. Dierckx, Riemer H. J. A. Slart, Ronald J. H. Borra, Niek H. J. Prakken
Summary: Automating cardiac function assessment using cardiac magnetic resonance imaging is faster and more reproducible than manual contour-tracing, but accurately tracing basal contours remains challenging. Comparing three automated post-processing software packages to manual assessment, it was found that Level 1 automation had wider limits of agreement compared to manual. However, in Level 2 automation, there was a balance between speed and accuracy, with more reliable software packages obtaining more accurate measurements.
Article
Cardiac & Cardiovascular Systems
Sanne A. Groeneveld, Feddo P. Kirkels, Maarten J. Cramer, Reinder Evertz, Kristina H. Haugaa, Pieter G. Postema, Niek H. J. Prakken, Arco J. Teske, Arthur A. M. Wilde, Birgitta K. Velthuis, Robin Nijveldt, Rutger J. Hassink
Summary: This study investigated the prevalence of mitral annulus disjunction (MAD) and mitral valve prolapse (MVP) in patients with idiopathic ventricular fibrillation (IVF). The results showed that the prevalence of inferolateral MAD and MVP was significantly higher in IVF patients compared to healthy controls.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Infectious Diseases
Marjan Wouthuyzen-Bakker, Marleen van Oosten, Wouter Bierman, Rik Winter, Andor Glaudemans, Riemer Slart, Marlous Toren-Wielema, Ignace Tielliu, Clark J. Zeebregts, Niek H. J. Prakken, Jean Paul de Vries, Ben R. Saleem
Summary: Vascular graft or endograft infection (VGEI) is a serious complication of vascular surgery, which has high morbidity and mortality rates. To diagnose and treat VGEI effectively, a multidisciplinary team of vascular surgeons, infectious disease specialists, medical microbiologists, radiologists, nuclear medicine specialists, and hospital pharmacists is required. A structured diagnostic, antibiotic, and surgical treatment algorithm can help guide clinical decision-making and improve the clinical outcome of patients with VGEI.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Biology
Nick D. van Rijsewijk, Jasper H. G. Helthuis, Andor W. J. M. Glaudemans, Marjan Wouthuyzen-Bakker, Niek H. J. Prakken, David J. Liesker, Ben R. Saleem, Riemer H. J. A. Slart
Summary: This study aimed to investigate the added value of possibly present lymph nodes in the diagnosis of vascular graft infection. Uptake and enlargement of lymph nodes is highly indicative for vascular graft infections but does not add to existing interpretation criteria.
