Review
Cardiac & Cardiovascular Systems
Margarita Brida, Daniel Lovric, Massimo Griselli, Fernando Riesgo Gil, Michael A. Gatzoulis
Summary: Heart failure is the leading cause of morbidity and mortality in adult patients with congenital heart disease. The nature of the underlying congenital heart disease affects the timing and severity of heart failure, and ongoing management is necessary. Drug therapy has some effect on left ventricle failure, but there is currently a lack of data on drug therapy for right ventricle and Fontan circulation failure. Cardiac resynchronization therapy is considered as a treatment option, while mechanical circulatory support and transplantation are last resorts in highly selected patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Jeremy P. Moore, Ariane Marelli, Luke J. Burchill, Henry Chubb, S. Lucy Roche, Ari M. Cedars, Paul Khairy, Ali N. Zaidi, Jan Janousek, David S. Crossland, Robert H. Pass, Jeffrey P. Jacobs, Jonathan N. Menachem, David S. Frankel, Sabine Ernst, Jim T. Vehmeijer, Mitchell Cohen
Summary: Heart failure and arrhythmia are the most important cardiovascular diseases among adults with congenital heart disease, and they often overlap and interact with each other. It is crucial for clinical management to recognize these interactions and have access to the available pharmacologic and interventional resources.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Patryk Leczycki, Maciej Banach, Marek Maciejewski, Agata Bielecka-Dabrowa
Summary: In recent decades, there has been a significant increase in the number of adults with congenital heart diseases (ACHD), necessitating thorough evaluation of their current condition. There is currently a lack of universal parameters or scales to easily assess the deterioration of ACHD patients' condition, emphasizing the need to identify widely available, cost-effective, and user-friendly factors. Studies have shown potential prognostic factors including echocardiography and magnetic resonance imaging, cardiopulmonary exercise testing, and biomarkers. However, further research is needed to create a specific assessment panel for patients with specific congenital heart diseases.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Yuta Seko, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Masayuki Shiba, Erika Yamamoto, Yusuke Yoshikawa, Yugo Yamashita, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Toshikazu Jinnai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Mamoru Toyofuku, Yutaka Furukawa, Kenji Ando, Kazushige Kadota, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura
Summary: Elderly patients with multiple comorbidities are more likely to develop newly diagnosed infections after admission for acute heart failure, which is associated with higher in-hospital and post-discharge mortality in patients with acute heart failure.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Alexander C. Egbe, William R. Miranda, C. Charles Jain, Crystal R. Bonnichsen, Jason H. Anderson, Joseph A. Dearani, Carole A. Warnes, Juan Crestanello, Heidi M. Connolly
Summary: Limited data are available on adults with congenital heart disease and stage D heart failure. This study aimed to determine the incidence of advanced heart failure in these patients, its relationship with all-cause mortality, and the impact of different therapies on mortality. The results showed that the incidence of advanced heart failure was higher in patients with severe or complex congenital heart disease and it was associated with a six-fold increase in mortality risk. Conventional cardiac intervention was associated with higher mortality risk compared to transplant listing. A longer interval between the onset of advanced heart failure and transplant evaluation decreased the likelihood of being listed for transplant.
CIRCULATION-HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Maria Fedchenko, Zacharias Mandalenakis, Kok Wai Giang, Annika Rosengren, Peter Eriksson, Mikael Dellborg
Summary: Patients with congenital heart disease have a higher risk of myocardial infarction compared to controls, and also a higher risk of developing new-onset heart failure, recurrent MI, or death after the index MI. Proper management of modifiable cardiovascular risk factors is crucial in reducing morbidity and mortality in these patients.
EUROPEAN HEART JOURNAL
(2021)
Article
Health Care Sciences & Services
Matthew T. Mefford, Ran Liu, Katia Bruxvoort, Lei Qian, Jonathan M. Doris, Sandra Y. Koyama, Hung Fu Tseng, Kristi Reynolds
Summary: The study found that influenza vaccination in heart failure patients was associated with a lower risk of mortality and cardiovascular mortality during the influenza season, but a higher risk of hospitalization. There was no significant association between influenza vaccination and all-cause mortality during the non-influenza season.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Medicine, General & Internal
John A. Robbins, Petra Buzkova, Joshua I. Barzilay, Jane A. Cauley, Howard A. Fink, Laura D. Carbone, Zhao Chen, Phyllis K. Stein, Rachel Elam, Kerry Sheets, Kenneth J. Mukamal
Summary: The impact of comorbidities like coronary heart disease on mortality after hip fracture in older adults is not well quantified. This study showed that the mortality rate was higher in individuals with coronary heart disease after hip fracture compared to those with incident heart failure.
AMERICAN JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Sarah Cohen, Aihua Liu, Fei Wang, Liming Guo, James M. Brophy, Michal Abrahamowicz, Judith Therrien, Luc M. Beauchesne, Elisabeth Bedard, Jasmine Grewal, Paul Khairy, Erwin Oechslin, S. Lucy Roche, Candice K. Silversides, Isabelle F. Vonder Muhll, Ariane J. Marelli
Summary: The study aimed to develop a risk prediction system for HF hospitalization in ACHD patients and successfully identified high-risk patients using predictors such as age, sex, CHD lesion severity, recent HFH history, and comorbidities. The risk scoring system showed excellent prediction performance.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Reaksmei Ly, Clement Karsenty, Pascal Amedro, Sarah Cohen, Olivia Domanski, Francois Godart, Jelena Radojevic, Guy Vaksmann, Nicole Naccache, Anissa Boubrit, Vincent Bataille, Sebastien Hascoet, Magalie Ladouceur
Summary: This study aimed to determine the predictive value of quality of life (QoL) on outcomes in adults with congenital heart disease (ACHD) and heart failure (HF). The study results showed that patients with poor QoL experience severe events more frequently, thus highlighting the importance of evaluating QoL and implementing rehabilitation programs to alter their trajectory.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Public, Environmental & Occupational Health
Marie Tindborg, Anders Koch, Mikael Andersson, Klaus Juul, Uka Wilhjelm Geisler, Bolette Soborg, Sascha Wilk Michelsen
Summary: The incidence rates of heart disease (HD) and congenital heart disease (CHD) were compared between young Inuit populations in Greenland and Denmark. It was found that the incidence rate of HD was lower in Greenland compared to Denmark, while the incidence rates of CHD were similar in both countries. Individuals of Inuit/mixed ethnicity had a higher risk of both HD and CHD compared to non-Inuit individuals in both countries.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Giulia Poretti, Stiljan Hoxha, Antonio Segreto, Gardellini Jacopo, Camilla Sandrini, Giuseppe Faggian, Alessandro Varrica, Massimo Chessa, Alessandro Giamberti, Giovanni Battista Luciani
Summary: Cryoablation for supraventricular arrhythmias in ACHD patients is a safe and effective procedure with a low risk of recurrence, and surgical treatment should be considered when further open-heart repair is needed.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Danielle S. Burstein, Joseph W. Rossano, Heather Griffis, Xuemei Zhang, Rachel Fowler, Benjamin Frischertz, Yuli Y. Kim, JoAnn Lindenfield, Jeremy A. Mazurek, Jonathan B. Edelson, Jonathan N. Menachem
Summary: Limited contemporary data exist regarding outcomes and resource use among adults with congenital heart disease and heart failure. This study compared outcomes and resource use between adults with congenital heart disease and heart failure (ACHD-HF) and non-ACHD with heart failure (HF-non-ACHD). The study found that ACHD-HF patients have increased emergency department and hospital resource use over the past 10 years, but are less likely to receive advanced heart failure therapies such as ventricular assist device (VAD) or transplant compared with non-ACHD heart failure patients.
Article
Medicine, General & Internal
Valentin Mertz, Yves Cottin, Sid Ahmed Bentounes, Julie Pastier-Debeaumarche, Romain Didier, Julien Herbert, Marianne Zeller, Gregory Y. H. Lip, Laurent Fauchier
Summary: The study aims to assess the prognosis of AF patients and found that patients with cardiac or extra-cardiac concomitant conditions have worse outcomes compared to patients with Lone AF.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Syed Shahyan Bakhtiyar, Sara Sakowitz, Konmal Ali, Nikhil L. Chervu, Arjun Verma, Ming-Sing Si, David D'Alessandro, Peyman Benharash
Summary: The study evaluates the survival rate after heart transplantation in adults with single and biventricular CHD and compares it to that of non-CHD transplant recipients. Single-ventricle physiology is associated with higher short-term mortality, but 10-year conditional survival is similar for biventricular CHD patients and most single-ventricle CHD patients, and notably better for biventricular CHD patients compared to non-CHD heart transplant recipients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Odilia Woudstra, Joey M. Kuijpers, Monique R. M. Jongbloed, Arie P. J. van Dijk, Gertjan T. Sieswerda, Hubert W. Vliegen, Anastasia D. Egorova, Philippine Kies, Anthonie L. Duijnhouwer, Danielle Robbers-Visser, Thelma C. Konings, Aeilko H. Zwinderman, Folkert J. Meijboom, Barbara J. M. Mulder, Berto J. Bouma
Summary: This study evaluated medication use in TGA-AtrSO patients and found that the use of RAAS inhibitors and beta-blockers can reduce mortality risk in symptomatic patients. However, no benefit of these medications was observed in the overall patient cohort.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2022)
Correction
Infectious Diseases
Maren Kummerow, Erica J. Shaddock, Kerstin Klipstein-Grobusch, Roos B. Barth, Diederick E. Grobbee, W. D. Francois Venter, Charles Feldman, Alinda Vos
SOUTHERN AFRICAN JOURNAL OF HIV MEDICINE
(2021)
Article
Infectious Diseases
Sarah E. van Riel, Kerstin Klipstein-Grobusch, Roos E. Barth, Diederick E. Grobbee, Charles Feldman, Erica Shaddock, Sarah L. Stacey, Willem D. F. Venter, Alinda G. Vos
Summary: The study identified a history of TB or pneumonia as an independent predictor of impaired lung function in an HIV-positive population in an urban African setting.
SOUTHERN AFRICAN JOURNAL OF HIV MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Surenjav Chimed, Pieter van der Bijl, Rodolfo de Paula Lustosa, Kensuke Hirasawa, Idit Yedidya, Federico Fortuni, Enno van Der Velde, Jose M. Montero-Cabezas, Nina Ajmone Marsan, Bernard J. Gersh, Victoria Delgado, Jeroen J. Bax
Summary: RV remodeling after STEMI is independently associated with increased mortality and HF hospitalization.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Review
Endocrinology & Metabolism
Roberta Lamptey, Maud P. Robben, Mary Amoakoh-Coleman, Daniel Boateng, Diederick E. Grobbee, Melanie J. Davies, Kerstin Klipstein-Grobusch
Summary: There is a lack of research on the association between structured diabetes self-management education (DSME) and glycemic control in low- and middle-income countries (LMICs). However, existing evidence suggests that structured DSME is associated with reductions in glycated hemoglobin in these countries, particularly in sub-Saharan Africa.
Article
Cardiac & Cardiovascular Systems
Maria Chiara Meucci, Steele C. Butcher, Xavier Galloo, Enno T. van der Velde, Nina Ajmone Marsan, Jeroen J. Bax, Victoria Delgado
Summary: Noninvasive LV myocardial work can be used to evaluate myocardial function and energetics in patients with chronic severe aortic regurgitation, and it is more accurate than afterload-dependent echocardiographic parameters.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2022)
Article
Infectious Diseases
Oda E. van den Berg, Erica J. Shaddock, Sarah L. Stacey, Charles Feldman, Roos E. Barth, Diederick E. Grobbee, Willem D. F. Venter, Kerstin Klipstein-Grobusch, Alinda G. Vos
Summary: The study found that HIV infection and ART use were not associated with reduced pulmonary function in an urban African population in Johannesburg, South Africa. Tuberculosis played a mediating role in the relationship between HIV, ART, and pulmonary function.
SOUTHERN AFRICAN JOURNAL OF HIV MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
M. Feijen, A. D. Egorova, E. T. van der Velde, M. J. Schalij, S. L. M. A. Beeres
Summary: Despite being at high risk for complications from COVID-19, patients with cardiac implantable electronic devices (CIED) in the Leiden area of the Netherlands did not experience significant excess mortality during the first peak of the pandemic. Strict adherence to preventive measures may have prevented substantial excess mortality in these vulnerable patients.
NETHERLANDS HEART JOURNAL
(2022)
Article
Health Care Sciences & Services
Roderick Willem Treskes, M. Elske Van den Akker-van Marle, Louise van Winden, Nicole van Keulen, Enno Tjeerd van der Velde, Saskia Beeres, Douwe Atsma, Martin Jan Schalij
Summary: This paper describes a cost-utility analysis of an eHealth intervention compared to regular follow-up in patients with acute myocardial infarction (AMI). The study found that eHealth intervention in the outpatient clinic setting for AMI patients is likely to be cost-effective compared to regular follow-up.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Medicine, General & Internal
Victor Williams, Alinda Vos, Kennedy Otwombe, Diederick E. Grobbee, Kerstin Klipstein-Grobusch
Summary: This study aims to describe the epidemiology of diabetes mellitus-tuberculosis comorbidity in Eswatini and identify best practices for integrating care for non-communicable diseases into TB services.
Review
Public, Environmental & Occupational Health
Victor Williams, Chukwuemeka Onwuchekwa, Alinda G. Vos, Diederick E. Grobbee, Kennedy Otwombe, Kerstin Klipstein-Grobusch
Summary: This study compiled evidence of changes in blood glucose during and after tuberculosis treatment in previously normoglycaemic patients. It was found that elevated blood glucose in normoglycaemic patients decreased by the end of treatment. Patients with hyperglycaemia at baseline were more likely to develop cavitary lung lesions and experienced poor treatment outcomes and higher post-treatment mortality.
GLOBAL HEALTH ACTION
(2022)
Article
Cardiac & Cardiovascular Systems
Wouter B. van Dijk, Ewoud Schuit, Rieke van der Graaf, Rolf H. H. Groenwold, Sara Laurijssen, Barbara Casadei, Marco Roffi, Seye Abimbola, Martine C. de Vries, Diederick E. Grobbee
Summary: This study evaluated the feasibility of implementing ESC guidelines on general cardiology in 102 countries and found that compliance varied based on the country's income level. High-income countries had better compliance, while low-income countries had lower compliance, largely due to lack of reimbursement and financial barriers.
EUROPEAN HEART JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Salisu Mohammed Ishaku, Kwame Adu-bonsaffoh, Natasha Housseine, Roberta Lamptey, Arie Franx, Diederick Grobbee, Charlotte E. Warren, Joyce L. Browne
Summary: This article aims to generate consensus-based recommendations for the prevention and screening of cardiometabolic and kidney diseases following hypertensive disorders in pregnancy (HDP) in low- and middle-income countries (LMICs). The recommendations provide practical and scalable approaches for effective screening and prevention of cardiometabolic disease following HDP in LMICs. Monitoring and evaluation of implementation of these recommendations provide opportunities for reducing the escalating burden of noncommunicable diseases in LMICs.
Article
Cardiac & Cardiovascular Systems
Wouter B. van Dijk, Artuur M. Leeuwenberg, Diederick E. Grobbee, Sabrina Siregar, Saskia Houterman, Edgar J. Daeter, Martine C. de Vries, Rolf H. H. Groenwold, Ewoud Schuit
Summary: A study in the Netherlands revealed that the EuroSCORE II model has good discriminative performance but consistently overestimates mortality risks in all types of major cardiothoracic surgical procedures. The values of individual predictors varied widely over time.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Steele C. Butcher, Federico Fortuni, Jose M. Montero-Cabezas, Rachid Abou, Mohammed El Mahdiui, Pieter van der Bijl, Enno T. van der Velde, Nina Ajmone Marsan, Jeroen J. Bax, Victoria Delgado
Summary: RVGCW is a novel parameter that provides an integrative analysis of RV systolic function and correlates more closely with invasively measured stroke volume and stroke volume index than other standard echocardiographic parameters. In patients with HFrEF, RVGWI, RVGCW, and RVGWE values were significantly lower, while values of RVGWVV were significantly higher compared to a healthy cohort.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2021)