Review
Cardiac & Cardiovascular Systems
Rodolfo Citro, Michele Bellino, Elisa Merli, Davide Di Vece, Mark V. Sherrid
Summary: There are two proposed causes of acute left ventricular ballooning: direct catecholamine toxicity or microvascular ischemia, referred to as Takotsubo syndrome, and sudden onset of latent left ventricular outflow tract obstruction in patients with underlying hypertrophic cardiomyopathy. Understanding the pathophysiology is crucial for correct diagnosis and guiding treatment.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Review
Cardiac & Cardiovascular Systems
Lorraine Lok-Wing Chiang, Shek Long Tsang, Jing Xian Lee, Mengqi Gong, Tong Liu, Gary Tse, Dong Chang, Ishan Lakhani, Ka Hou Christien Li
Summary: Reduced LVEF, both as a categorical and continuous variable, is associated with increased mortality risk in Takotsubo cardiomyopathy patients. However, the presence of apical ballooning did not show a significant link with mortality risk.
HEART FAILURE REVIEWS
(2021)
Article
Cardiac & Cardiovascular Systems
John S. Dayco, Riyad Y. Kherallah, Josh Epstein, Oluwole Adegbala, Christina Reji, Karim Dirani, Carlos Oviedo, Luis Afonso
Summary: Standard echocardiographic indices of diastolic function have limited diagnostic value in patients with Takotsubo cardiomyopathy and are not as accurate as invasive measurements of left ventricular end-diastolic pressure and left ventricular pre-A wave diastolic pressure. Therefore, invasive measurements should be used for optimal risk stratification and management in these patients.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rui Shi, Ke Shi, Shan Huang, Xiang Li, Chun-Chao Xia, Yuan Li, Sen He, Zhen-Lin Li, Yong He, Ying-Kun Guo, Zhi-Gang Yang
Summary: The study found that LA phasic function was severely impaired in HCM patients with HFpEF, while LV function was not further impaired compared to non-HF patients.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Multidisciplinary Sciences
Qing Zou, Rong Xu, Xiao Li, Hua-yan Xu, Zhi-gang Yang, Yi-ning Wang, Hai-ming Fan, Ying-kun Guo
Summary: This study found that mitral regurgitation (MR) is common in left ventricular noncompaction (LVNC) patients, and those with MR exhibit more severe morphological and functional changes in their hearts, including deteriorated cardiac function and a higher incidence of arrhythmia. Hypertrabeculation is not a significant factor affecting structure and function at the heart failure stage in LVNC patients.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Hamada Alsheikh, Nour Shaheen, Wageih Saber, Mostafa Meshref, Yara Amro, Ahmed Shaheen, Mahmoud Galal Ahmed, Sarya Swed
Summary: A patient with high-risk myocardial infarction was retroactively diagnosed with TCM after normal epicardial coronaries were revealed in coronary angiography. The patient underwent surgical repair of VSR and had a good recovery.
Article
Cardiac & Cardiovascular Systems
Mirae Lee, Alon Shechter, Donghee Han, Long-Co Nguyen, Min Sun Kim, Daniel S. Berman, Florian Rader, Robert J. Siegel
Summary: This study evaluated the morphologic progression of the left ventricle (LV) in apical hypertrophic cardiomyopathy (AHC) patients using serial echocardiograms. The results showed that about half of the patients had changes in LV morphology, with some patients experiencing further hypertrophic involvement and the development of apical pouches or aneurysms. The study also found that patients with more severe LV hypertrophy and apical involvement had higher rates of adverse clinical events.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Anthony Matta, Clement Delmas, Francesco Campelo-Parada, Thibault Lhermusier, Frederic Bouisset, Meyer Elbaz, Vanessa Nader, Stephanie Blanco, Jerome Roncalli, Didier Carrie
Summary: Takotsubo cardiomyopathy is a clinical condition related to heart failure, with sympathetic nerve stimulation and catecholamine storm playing a role in its development. While the clinical course of the disease is generally mild, life-threatening complications can occur. Coronary angiography, left ventriculogram, transthoracic echocardiography and cardiac magnetic resonance imaging are key tools for diagnosis. Treatment usually involves conventional heart failure therapy, unless the patient is in critical condition or experiencing complications.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Claudia Stoellberger, Josef Finsterer
Summary: The relationship between Takotsubo syndrome (TTS), left ventricular hypertrabeculation/noncompaction (LVHT), and neuromuscular disorders (NMD) was summarized. It appears that LVHT may disappear after TTS, but the exact mechanism remains unclear.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Multidisciplinary Sciences
Jessica Mao, Eric Xie, Ela Chamera, Joao A. C. Lima, Jonathan Chrispin
Summary: The study aimed to use CMR to evaluate changes in cardiac structure and function of PVC CM patients following catheter ablation. PVC origin in the RV was associated with persistently reduced LVEF after ablation, while scar burden was not correlated with cardiac function or post-ablation recovery of function.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Mark Sherrid, Samuel Bernard, Nidhi Tripathi, Yash Patel, Vivek Modi, Leon Axel, Soheila Talebi, Brian B. Ghoshhajra, Danita Y. Sanborn, Muhamed Saric, Elizabeth Adlestein, Isabel Castro Alvarez, Yuhe Xia, Daniel G. Swistel, Daniele Massera, Michael A. Fifer, Bette Kim
Summary: This study investigated the frequency of mid-LV obstruction in apical aneurysms of hypertrophic cardiomyopathy (HCM). The results showed that 95% of patients with aneurysms had mid-LV obstruction. Further research is needed to explore the relationship between mid-LV obstruction and aneurysms.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ke Shi, Shan Huang, Xiang Li, Hua-Yan Xu, Meng-Xi Yang, Yuan Li, Ying-Kun Guo, Zhi-Gang Yang
Summary: This study examines the effects of obesity on left ventricular remodeling and long-term clinical outcomes in Chinese patients with hypertrophic cardiomyopathy. The results show that obesity is associated with increased left ventricular mass, impaired strain indices, and an elevated risk of future adverse clinical outcomes.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Sarah Chiu, Rohith Nayak, Bryan Lin, Lewei Duan, Albert Yuh-Jer Shen, Ming-Sum Lee
Summary: Patients with takotsubo syndrome, compared to those with acute myocardial infarction (AMI), tend to be older, more likely to be women, and have better long-term outcomes.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Rocco Antonio Montone, Giulia La Vecchia, Marco Giuseppe Del Buono, Antonio Abbate, Tommaso Sanna, Daniela Pedicino, Giampaolo Niccoli, Massimo Antonelli, Filippo Crea
Summary: This review article provides an overview of the acute clinical manifestations of patients with Takotsubo syndrome (TTS), highlighting predictors of worse short-term outcomes and challenges in the management of TTS-related complications in the acute care setting.
CURRENT PROBLEMS IN CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Rasheed Durowoju, Song Li, Gary S. Huang
Summary: Takotsubo syndrome (TTS) is evaluated by monitoring left ventricular ejection fraction (LVEF), but there is limited data on the correlation between echocardiographic findings and long-term outcomes. This study assessed clinical outcomes in TTS patients and their association with echocardiographic parameters. The results showed no significant association between echocardiographic parameters and clinical end points, with a low readmission rate and a majority of patients experiencing normalization of LVEF.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)