Article
Clinical Neurology
Igor A. Kelmanson
Summary: OSAS is associated with increased P-wave dispersion (PWD), which may predispose to atrial tachyarrhythmias. Meta-analysis showed that OSAS patients have higher PWD values, and there is a positive correlation between apnea-hypopnea indices (AHI) and PWD.
SLEEP AND BREATHING
(2023)
Review
Health Care Sciences & Services
Sy Duong-Quy, Hoang Nguyen-Huu, Dinh Hoang-Chau-Bao, Si Tran-Duc, Lien Nguyen-Thi-Hong, Thai Nguyen-Duy, Tram Tang-Thi-Thao, Chandat Phan, Khue Bui-Diem, Quan Vu-Tran-Thien, Thu Nguyen-Ngoc-Phuong, Vinh Nguyen-Nhu, Huong Le-Thi-Minh, Timothy Craig
Summary: Obstructive Sleep Apnea (OSA) is a common disease that is often underestimated and undertreated in all age groups. Personalized diagnosis and treatment approaches are necessary for clinical practice due to morphological differences, clinical phenotype diversity, and variations in diagnosis and treatment of OSA in children and adults. Treatment should be based on individual tolerance to sleep-quality-related parameters, the harmful effects of hypoxia on the cardiovascular system, and patients' comorbidities.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Clinical Neurology
Hiwa Mohammadi, Ardalan Aarabi, Mohammad Rezaei, Habibolah Khazaie, Serge Brand
Summary: The study found that individuals with OSAS have significantly lower spindle density in N3 and shorter spindle duration in N2 compared to healthy controls. Furthermore, individuals with mild OSAS showed sleep spindle characteristics more similar to healthy controls, unlike those with moderate and severe OSAS.
FRONTIERS IN NEUROLOGY
(2021)
Article
Engineering, Biomedical
Xin-Xue Lin, Phone Lin, En-Hau Yeh, Gi-Ren Liu, Wan-Ching Lien, Yuguang Fang
Summary: In this paper, an AI-based framework called RAPIDEST is proposed to detect OSA. The framework only requires EEG signals, simplifying the signal collection process and reducing the complexity of severity determination for apnea and hypopnea.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Otorhinolaryngology
Diogo Raposo, Marco Menezes, Joao Rito, Mafalda Trindade-Soares, Cristina Adonis, Helena Cristina Loureiro, Filipe Freire
Summary: DISE findings varied between surgically naive children and those with persistent obstructive sleep apnea after adenotonsillectomy. Increased obstruction at the tongue base and multilevel obstruction predicted a lower saturation nadir in children with persistent obstructive sleep apnea after adenotonsillectomy.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Medicine, General & Internal
Amalia Ioanna Moula, Iris Parrini, Cecilia Tetta, Fabiana Luca, Gianmarco Parise, Carmelo Massimiliano Rao, Emanuela Mauro, Orlando Parise, Francesco Matteucci, Michele Massimo Gulizia, Mark La Meir, Sandro Gelsomino
Summary: Atrial fibrillation (AF) is the most common arrhythmia, with its incidence increasing with age and comorbidities. Obstructive sleep apnea (OSA) is a chronic sleep disorder more commonly found in older men. Previous studies have shown a link between OSA and AF, although the prevalence of OSA in AF patients remains unknown due to underdiagnosis. This meta-analysis investigated the association between OSA and AF, using data from 54,271 patients. A strong link was found between these two disorders, with the incidence of AF being 88% higher in patients with OSA. Age and hypertension were found to independently strengthen this association, indicating that treating OSA may help reduce AF recurrence. Further research is needed to confirm these findings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Nutrition & Dietetics
Silvia Conde, Fatima O. Martins, Sara S. Dias, Paula Pinto, Cristina Barbara, Emilia C. Monteiro
Summary: This study investigated the effect of caffeine consumption on patients with obstructive sleep apnea (OSA) and found that higher caffeine consumption does not alter the variables related to the disease.
Article
Endocrinology & Metabolism
M. Leentjens, Abdulmohsen Alterki, Mohamed Abu-Farha, P. F. N. Bosschieter, CAL. de Raaff, CEE. de Vries, Eman Al Shawaf, Thangavel Alphonse Thanaraj, Irina Al-Khairi, Preethi Cherian, Arshad Channanath, Sina Kavalakatt, B. A. van Wagensveld, N. de Vries, Jehad Abubaker
Summary: This study found significantly increased levels of ANGPTL7 in both the circulation and adipose tissue of patients with OSA, which were associated with increased inflammation and OSA severity. Bariatric surgery was shown to significantly reduce ANGPTL7 levels and improve OSA.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Critical Care Medicine
Samuel T. Kuna, David M. Reboussin, Elsa S. Strotmeyer, Richard P. Millman, Gary Zammit, Michael P. Walkup, Thomas A. Wadden, Rena R. Wing, F. Xavier Pi-Sunyer, Adam P. Spira, Gary D. Foster
Summary: Intensive lifestyle intervention for weight loss can lead to reduced severity of obstructive sleep apnea in individuals with type 2 diabetes mellitus, and this improvement can be sustained over a 10-year period. The amount of weight loss is related to the improvement in OSA severity, and ILI may play a significant role in this improvement.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Clinical Neurology
Vincent Mysliwiec, Matthew S. Brock, Kristi E. Pruiksma, Casey L. Straud, Daniel J. Taylor, Shana Hansen, Shannon N. Foster, Sara Mithani, Sarah Zwetzig, Kelsi Gerwell, Stacey Young-McCaughan, Tyler Powell, John A. Blue Star, Daniel G. Cassidy, Jim Mintz, Alan L. Peterson
Summary: This study aimed to characterize the sleep disorders of insomnia, obstructive sleep apnea (OSA), and comorbid insomnia and OSA (COMISA) in active duty military personnel. The results showed that military personnel with insomnia only and COMISA had more severe symptoms of sleep disorders, sleep-related impairment, fatigue, and psychiatric disorders compared to those with OSA alone. These findings highlight the importance of comprehensive assessment for sleep-related impairment, sleep, and comorbid disorders in military personnel with clinically significant sleep disturbances.
Review
Medicine, General & Internal
Youmeng Wang, Christoph Schoebel, Thomas Penzel
Summary: Sleep apnea is a common chronic condition that can be classified as obstructive sleep apnea (OSA) or central sleep apnea (CSA). Patients with heart failure often have a combination of OSA and CSA, known as complex sleep apnea syndrome. This review examines different treatment options for OSA in heart failure patients, including surgical and non-surgical approaches, and discusses the potential positive and negative outcomes of these treatments. The review also provides references and suggestions for future research on CSA treatment options.
FRONTIERS IN MEDICINE
(2022)
Article
Clinical Neurology
Frederic Schlemmer, Maeva Zysman, Bruno Ribeiro Baptista, Etienne Audureau, Ala Covali Noroc, Audrey Ridoux, Genevieve Derumeaux, Serge Adnot, Bernard Maitre, Philippe le Corvoisier, Sophie Lanone, Jorge Boczkowski, Laurent Boyer
Summary: Obstructive sleep apnea leads to chronic intermittent hypoxia, which may induce adaptative cardiovascular pathways. Activation of autophagy plays a significant role in protecting against cardiovascular events in patients with OSA.
Article
Dentistry, Oral Surgery & Medicine
Adrian Ujin Yap, Madeleine Wan Yong Tan, Sharon Hui Xuan Tan, Ai Ping Chua
Summary: This study examined the temporal relationships between apnea-hypopnea (AH) and sleep bruxism (SB) events and their correlation with respiratory/sleep indexes in patients with obstructive sleep apnea (OSA) and SB. The majority of AH events were unrelated to SB events. When they were related, SB events often occurred after AH events, indicating a specific form of secondary SB triggered by sleep micro-arousals. SB events were associated with total sleep time, but not with the AH index.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Health Care Sciences & Services
Geetha Kandasamy, Tahani Almeleebia
Summary: This study aimed to assess OSA and the relationship between AHI and polysomnographic characteristics in OSA patients. The results showed a significant prevalence of obesity and high frequency of OSA in men, with polysomnography being the primary method for early detection and treatment of the condition.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Clinical Neurology
Mohit, Ashutosh Shrivastava, Pooran Chand
Summary: Obstructive sleep apnea (OSA) is characterized by recurrent episodes of upper airway obstruction during sleep and is influenced by genetic factors such as heritability and phenotypic co-factors. Inflammatory cytokine polymorphism and obesity are strongly associated with OSA development, and advanced techniques can facilitate new discoveries and reduce the risk of developing OSA.
Article
Transplantation
Kerem Can Yilmaz, Orcun Ciftci, Arzu Neslihan Akgun, Haldun Muderrisoglu, Sedat Boyacioglu, Asuman Nihan Haberal, Gokhan Moray, Mehmet Haberal
EXPERIMENTAL AND CLINICAL TRANSPLANTATION
(2020)
Article
Cardiac & Cardiovascular Systems
Kerem Can Yilmaz, Sirel Sur Gungor, Orcun Ciftci, Ahmet Akman, Haldun Muderrisoglu
Article
Emergency Medicine
Olgun Celik, Orcun Ciftci, Ibrahim Haldun Muderrisoglu
Summary: The study found that the use of MELD-XI score can effectively predict the 30-day in-hospital mortality in patients with ST elevation myocardial infarction. MELD-XI score is significantly correlated with left ventricular ejection fraction and age, and serves as a predictor for the survival status of patients.
HONG KONG JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Kerem Can Yilmaz, Arzu Neslihan Akgun, Orcun Ciftci, Serpil Eroglu, Bahar Pirat, Elif Sade, Melek Ulucam, Bulent Ozin, Haldun Muderrisoglu
Article
Cardiac & Cardiovascular Systems
Berrin Er, Meltem Simsek, Mehmet Yildirim, Burcin Halacli, Serpil Ocal, Ebru Ortac Ersoy, Ahmet Ugur Demir, Arzu Topeli
Summary: This study found a significant association between TRF + VI measured by ultrasonography within 36 hours of intubation lower than 21mm and weaning failure in critically-ill patients. It can serve as a predictive factor for weaning failure, highlighting the importance of this measurement in assessing patients prior to weaning.
RESPIRATORY MEDICINE
(2021)
Article
Food Science & Technology
Z. Begum Kalyoncu, Ahmet U. Demir, Aylin Ayaz
Summary: A Culinary Acculturation Assessment Inventory (CAAI) was developed using visual items to measure the impact of immigration on immigrants' food choices. The study found that CAAI is a reliable and valid measure of culinary acculturation of immigrant population, which can be adapted and used in other countries.
FOOD QUALITY AND PREFERENCE
(2021)
Article
Respiratory System
Oguz Karcioglu, Sevinc Sarinc Ulasli, Ahmet Ugur Demir
Summary: This study aimed to investigate the role of 4-meter gait speed (4mGS) in evaluating exercise capacity in COPD patients. The results showed a significant correlation between 4mGS and peak VO2 values, 6-minute walking test distance, and the general medical status of COPD patients. Considering its easy applicability and reproducibility, 4mGS seems to be an important method for monitoring exercise capacity in COPD patients.
TUBERKULOZ VE TORAKS-TUBERCULOSIS AND THORAX
(2022)
Letter
Public, Environmental & Occupational Health
Ahmet U. Demir, Ceprail Simsek, Elif Altundas Hatman, Ceyda Sahan, Alp Ergor, Yucel Demiral
OCCUPATIONAL MEDICINE-OXFORD
(2022)
Article
Medicine, General & Internal
Cigdem Ozdilekcan, Hikmet Firat, Ahmet Ugur Demir, Melike Yuceege, Bulent Devrim Akcay
Summary: The study found that pandemic-related changes had negative effects on sleep quality and social lives of sleep apnea patients, and also influenced the adherence to positive airway pressure (PAP) treatment in obstructive sleep apnea (OSA) patients. Patients with poor sleep quality had more difficulties with mask use and adjustments in PAP treatment. Most patients did not change their regular PAP use habits during the pandemic period.
IRANIAN RED CRESCENT MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Burak Ozkan, Abbas Albayati, Kerem C. Yilmaz, Orcun Ciftci, Bulent Ozin, Cagri A. Uysal, Nilgun Markal Ertas
Summary: The double layer closure of exposed cardiac implants using large breast fasciocutaneous flap after subpectoral placement of pulse generator and leads provides durable and reliable coverage for elderly patients with multiple comorbidities. No flap loss or wound dehiscence was observed during the follow-up period.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Urology & Nephrology
Kerem Can Yilmaz, Arzu Neslihan Akgun, Suzan Keskin, Orcun Ciftci, Gokhan Moray, Haldun Muderrisoglu, Mehmet Haberal
SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION
(2020)
Article
Emergency Medicine
Casit Olgun Celik, Orcun Ciftci, Murat Muratoglu, Ibrahim Haldun Muderrsioglu
Article
Cardiac & Cardiovascular Systems
Ersin Doganozu, Orcun Ciftci, Senem Hasirci, Kerem Can Yilmaz, Emir Karacaglar, Leyla Elif Sade, Ibrahim Haldun Muderrisoglu, Mehmet Bulent Ozin
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
(2020)
Article
Urology & Nephrology
Emir Karacaglar, Arzu Akgun, Orcun Ciftci, Nur Altiparmak, Haldun Muderrisoglu, Mehmet Haberal
SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION
(2019)
Article
Health Care Sciences & Services
Guvenc Kockaya, Gulpembe Ergin Oguzhan, Bulent Ozin, Kerem Can Yilmaz, Orcun Ciftci, Filiz Cavus, Amir Mustapha Sharaf, Nazim Buyuktuna, Tansu Buyukisik, Mete Saylan
JOURNAL OF PHARMACEUTICAL HEALTH SERVICES RESEARCH
(2019)