Article
Cardiac & Cardiovascular Systems
Alexander Stevenson, Jonathan J. H. Bray, Laura Tregidgo, Mahmood Ahmad, Anika Sharma, Alexander Ng, Atif Siddiqui, Ali A. Khalid, Keiran Hylton, Adrian Ionescu, Rui Providencia, Ali Kirresh
Summary: This study evaluated the predictive value of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging for prognosis in patients with cardiac sarcoidosis. The results showed that patients with LGE on CMR had a significantly increased risk of ventricular arrhythmias and all-cause mortality.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Alexander Stevenson, Jonathan J. H. Bray, Laura Tregidgo, Mahmood Ahmad, Anika Sharma, Alexander Ng, Atif Siddiqui, Ali A. Khalid, Keiran Hylton, Adrian Ionescu, Rui Providencia, Ali Kirresh
Summary: This systematic review and meta-analysis evaluated the predictive value of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging for prognosis in patients with cardiac sarcoidosis. The study found that patients with LGE on CMR had a higher risk of ventricular arrhythmias and all-cause mortality compared to those without LGE. In addition, the presence of biventricular LGE was associated with a significantly increased risk of ventricular arrhythmias.
JACC-CARDIOVASCULAR IMAGING
(2023)
Review
Medicine, General & Internal
Osamu Manabe, Noriko Oyama-Manabe, Tadao Aikawa, Satonori Tsuneta, Nagara Tamaki
Summary: Sarcoidosis, a systemic granulomatous disease, can affect various organs with cardiac involvement being a leading cause of mortality. The clinical manifestations of cardiac sarcoidosis are diverse, ranging from asymptomatic to life-threatening conditions. Imaging techniques, including positron emission tomography and cardiac magnetic resonance imaging, play a crucial role in diagnosing and evaluating cardiac sarcoidosis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Sebastian Weingaertner, Oemer B. Demirel, Francisco Gama, Iain Pierce, Thomas A. Treibel, Jeanette Schulz-Menger, Mehmet Akcakaya
Summary: This study proposes a method to obtain phase-resolved late gadolinium enhancement (LGE) images using cardiac magnetic resonance imaging. The method involves three steps and has been evaluated in phantom imaging, healthy subjects, and patients. The results demonstrate reliable imaging in the phantom and healthy subjects, while the imaging resolution and noise resilience in patients are lower compared to the reference technique. The proposed technique shows potential in integrating the advantages of phase-resolved cardiac magnetic resonance with LGE imaging, but further improvements are needed for clinical use.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yasutoshi Ohta, Emi Tateishi, Yoshiaki Morita, Tatsuya Nishii, Akiyuki Kotoku, Hiroki Horinouchi, Midori Fukuyama, Tetsuya Fukuda
Summary: The study demonstrates the feasibility of optimizing TI on Look-Locker images using deep learning and a smartphone.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Bradley S. Lander, Yanling Zhao, Kohei Hasegawa, Mathew S. Maurer, Albree Tower-Rader, Michael A. Fifer, Muredach P. Reilly, Yuichi J. Shimada
Summary: This multicenter case-control study demonstrates that plasma proteomics profiling can effectively distinguish patients with and without late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM). By identifying patients with a high pre-test probability of having LGE, this study lays the groundwork for establishing a panel of circulating protein biomarkers to improve clinical decision-making and utilization of cardiac magnetic resonance imaging (CMR).
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Kun Liu, Zhongyuan Cai, Xiaoqin Chi, Bilun Kang, Shengxiang Fu, Xiangjie Luo, Zhi-Wei Lin, Hua Ai, Jinhao Gao, Hongyu Lin
Summary: This study reports a new strategy to improve the performance of nanoparticle-based T1 contrast agents by utilizing the photoinduced super-hydrophilic assistance (PISA) effect. By doping gadolinium into citrate-coated titanium dioxide ellipsoidal nanoparticles (GdTi-SC NPs), the r1 value of the nanoparticles significantly increases upon UV irradiation. The existence of the PISA effect is confirmed by the reduced water contact angle and increased surface hydroxyl groups, leading to enhanced paramagnetic relaxation enhancement (PRE) efficiency and improved imaging performance. In vivo MRI experiments on rats demonstrate that GdTi-SC NPs can serve as a high-performance contrast agent for sensitive imaging of blood vessels and accurate diagnosis of vascular lesions, indicating the success of the proposed strategy.
Article
Cardiac & Cardiovascular Systems
Panithaya Chareonthaitawee, Matthias Gutberlet
Summary: Myocarditis refers to inflammation of the myocardium based on various findings. It can be caused by infectious agents, autoimmune diseases, vaccines, environmental factors, toxins, and drug hypersensitivity. Sarcoid myocarditis is recognized as an important cause of cardiomyopathy in patients with systemic sarcoidosis. The clinical presentation and involvement of the myocardium vary depending on the cause and stage of the disease. Imaging techniques, such as cardiac magnetic resonance and positron emission tomography, are crucial for diagnosis and prognosis. This review focuses on multimodality imaging approaches for the diagnosis and management of myocarditis and cardiac sarcoidosis, discussing current knowledge and future directions.
CIRCULATION-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Chadi Ayoub, Michael Chetrit, Deborah H. Kwon, Christine L. Jellis, Paul C. Cremer, Michael A. Bolen, Scott D. Flamm, Allan L. Klein
Summary: This review discusses the utilization of cardiac magnetic resonance imaging in the assessment of pericardial diseases, including the evaluation of pericardial sequences and the identification of pericardial inflammation, constriction, and effusion in clinical settings.
CIRCULATION-CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Jie Wang, Jinquan Zhang, Nisha Hosadurg, Yoshitaka Iwanaga, Yuxin Chen, Wei Liu, Ke Wan, Amit R. Patel, Eleanor C. Wicks, Georgios V. Gkoutos, Yuchi Han, Yucheng Chen
Summary: This study aimed to assess the prognostic value of right ventricular ejection fraction (RVEF) and right ventricular late gadolinium enhancement (LGE) in known or suspected cardiac sarcoidosis (CS). A total of eight studies were included, involving 899 patients with a mean follow-up duration of 3.2 years. The results showed that both right ventricular systolic dysfunction and right ventricular LGE were associated with adverse events, and right ventricular LGE had good discrimination in identifying CS patients at high risk of sudden cardiac death (SCD).
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Jie Wang, Jinquan Zhang, Nisha Hosadurg, Yoshitaka Iwanaga, Yuxin Chen, Wei Liu, Ke Wan, Amit R. Patel, Eleanor C. Wicks, Georgios V. Gkoutos, Yuchi Han, Yucheng Chen
Summary: This study systematically assessed the prognostic value of right ventricular ejection fraction (RVEF) and right ventricular late gadolinium enhancement (LGE) in cardiac sarcoidosis (CS). The results showed that both RVEF and RV LGE were associated with adverse events. In addition, RV LGE had good discrimination in identifying CS patients at high risk of sudden cardiac death (SCD).
JACC-CARDIOVASCULAR IMAGING
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Seitaro Oda, Kosuke Morita, Masafumi Kidoh, Yasunori Nagayama, Takeshi Nakaura, Yuichiro Shirahama, Yuta Tsurusaki, Kenichi Matsushita, Kenichi Tsujita, Toshinori Hirai
Summary: Additional digital content can be found in the text.
CIRCULATION-CARDIOVASCULAR IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Klas Berggren, Daniel Ryd, Einar Heiberg, Anthony H. Aletras, Erik Hedstrom
Summary: By combining phase-encoding undersampling with super-resolution neural networks, high-resolution fetal cine cardiac MR images can be achieved with shorter acquisition time, potentially improving the success rate of fetal MR imaging while maintaining image quality.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Health Care Sciences & Services
Oleg Orlov, Aref Asfour, Dmitry Shchekochikhin, Zainab Magomedova, Alexandra Bogdanova, Anna Komarova, Maxim Podianov, Grigory Gromyko, Ekaterina Pershina, Alexey Nesterov, Alexandra Shilova, Natalya Ionina, Dennis Andreev
Summary: TIC is a reversible subtype of cardiomyopathy that can be distinguished from DCM using CMR. TIC patients have smaller cardiac dimensions compared to DCM patients, while LGE is more common in DCM.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, Research & Experimental
Huan Li, Zijuan Hai, Liwei Zou, Lele Zhang, Lulu Wang, Longsheng Wang, Gaolin Liang
Summary: This study found that a gadolinium nanoparticle, instructed by gamma-glutamyl transpeptidase (GGT) and formed intracellularly, exhibits different magnetic resonance properties at low and high magnetic fields, making it suitable for enhancing T-1 and T-2 MRI imaging of liver tumors respectively.
