Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes

Exosomes secreted by placental stem cells selectively inhibit growth of aggressive prostate cancer cells

(2018) Taylor C. Peak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379

(2018) K. P. O’Brien et al.   ONCOGENE

Role of stem cell derived exosomes in tumor biology

(2017) Aman Sharma   INTERNATIONAL JOURNAL OF CANCER

Human mesenchymal stem cell-derived iron oxide exosomes allow targeted ablation of tumor cells via magnetic hyperthermia

(2017) Ursula Altanerova et al.   International Journal of Nanomedicine

Concise Review: MSC-Derived Exosomes for Cell-Free Therapy

(2017) Donald G. Phinney et al.   STEM CELLS

Role of stem cell-derived exosomes in cancer

(2017) Junyi Wu et al.   Oncology Letters

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

(2016) Yufang Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells

(2016) Johannes Leibacher et al.   Stem Cell Research & Therapy

Treatment of advanced gastrointestinal tumors with genetically modified autologous mesenchymal stromal cells (TREAT-ME1): study protocol of a phase I/II clinical trial

(2015) Hanno Niess et al.   BMC CANCER

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Mesenchymal stem cells expressing therapeutic genes induce autochthonous prostate tumour regression

(2014) Alberto Abrate et al.   EUROPEAN JOURNAL OF CANCER

Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery

(2014) Luisa Pascucci et al.   JOURNAL OF CONTROLLED RELEASE

Comparison of human mesenchymal stem cells derived from dental pulp, bone marrow, adipose tissue, and umbilical cord tissue by gene expression

(2013) Peter Stanko et al.   BIOMEDICAL PAPERS-OLOMOUC

Complete regression of glioblastoma by mesenchymal stem cells mediated prodrug gene therapy simulating clinical therapeutic scenario

(2013) Cestmir Altaner et al.   INTERNATIONAL JOURNAL OF CANCER

Characterization of Mesenchymal Stem Cells of “No-Options” Patients with Critical Limb Ischemia Treated by Autologous Bone Marrow Mononuclear Cells

(2013) Cestmir Altaner et al.   PLoS One

Human adipose tissue-derived mesenchymal stem cells: Characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas

(2011) Seung Ah Choi et al.   EUROPEAN JOURNAL OF CANCER

Human adipose tissue-derived mesenchymal stem cells expressing yeast cytosinedeaminase::uracil phosphoribosyltransferase inhibit intracerebral rat glioblastoma

(2011) Veronika Altanerova et al.   INTERNATIONAL JOURNAL OF CANCER

Stem Cell Based Cancer Gene Therapy

(2011) Marina Cihova et al.   MOLECULAR PHARMACEUTICS

Mesenchymal stem cells as cellular vehicles for delivery of nanoparticles to brain tumors

(2010) Mathilde Roger et al.   BIOMATERIALS

Mesenchymal Stem Cells Modified with a Single-Chain Antibody against EGFRvIII Successfully Inhibit the Growth of Human Xenograft Malignant Glioma

(2010) Irina V. Balyasnikova et al.   PLoS One

HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells

(2009) Miroslava Matuskova et al.   CANCER LETTERS

Adipose Tissue–derived Mesenchymal Stem Cells Expressing Prodrug-converting Enzyme Inhibit Human Prostate Tumor Growth

(2009) Ilaria T Cavarretta et al.   MOLECULAR THERAPY

Prodrug cancer gene therapy

(2008) Cestmir Altaner   CANCER LETTERS

Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice

(2008) Lucia Kucerova et al.   JOURNAL OF GENE MEDICINE