Genome-wide CNV analysis in 221 unrelated patients and targeted high-throughput sequencing reveal novel causative candidate genes for colorectal adenomatous polyposis

Germline Mutations in the Spindle Assembly Checkpoint Genes BUB1 and BUB3 Are Risk Factors for Colorectal Cancer

(2013) Richarda M. de Voer et al.   GASTROENTEROLOGY

Exome Resequencing Identifies Potential Tumor-Suppressor Genes that Predispose to Colorectal Cancer

(2013) Christopher G. Smith et al.   HUMAN MUTATION

Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis

(2013) Frederik J Hes et al.   JOURNAL OF MEDICAL GENETICS

High Expression of KIF26B in Breast Cancer Associates with Poor Prognosis

(2013) Qun Wang et al.   PLoS One

Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer

(2013) Alexandra E. Gylfe et al.   PLoS Genetics

Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes

(2013) Slavé Petrovski et al.   PLoS Genetics

Rare De Novo Germline Copy-Number Variation in Testicular Cancer

(2012) Zsofia K. Stadler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas

(2012) Antje Brockschmidt et al.   BRAIN

Germline copy number variations and cancer predisposition

(2012) Ana Cristina Victorino Krepischi et al.   Future Oncology

Prevalence and Phenotypes of APC and MUTYH Mutations in Patients With Multiple Colorectal Adenomas

(2012) Shilpa Grover et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer

(2012) Jérémie H Lefevre et al.   JOURNAL OF HUMAN GENETICS

Systematic Meta-Analyses and Field Synopsis of Genetic Association Studies in Colorectal Cancer

(2012) E. Theodoratou et al.   JNCI-Journal of the National Cancer Institute

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

(2012) Claire Palles et al.   NATURE GENETICS

Duplication of CXC chemokine genes on chromosome 4q13 in a melanoma-prone family

(2012) Xiaohong R. Yang et al.   Pigment Cell & Melanoma Research

Rare Copy Number Variants Observed in Hereditary Breast Cancer Cases Disrupt Genes in Estrogen Signaling and TP53 Tumor Suppression Network

(2012) Katri Pylkäs et al.   PLoS Genetics

Recurrent Targeted Genes of Hepatitis B Virus in the Liver Cancer Genomes Identified by a Next-Generation Sequencing–Based Approach

(2012) Dong Ding et al.   PLoS Genetics

Unexplained polyposis: a challenge for geneticists, pathologists and gastroenterologists

(2011) C Mongin et al.   CLINICAL GENETICS

Proteotoxic stress of cancer: Implication of the heat-shock response in oncogenesis

(2011) Chengkai Dai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Implications of gene copy-number variation in health and diseases

(2011) Suhani H Almal et al.   JOURNAL OF HUMAN GENETICS

The epigenetics of (hereditary) colorectal cancer

(2010) Ramprasath Venkatachalam et al.   CANCER GENETICS AND CYTOGENETICS

Germline copy number variation and cancer risk

(2010) Roland P Kuiper et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

De novo rates and selection of large copy number variation

(2010) A. Itsara et al.   GENOME RESEARCH

Mapping of equine cerebellar abiotrophy to ECA2 and identification of a potential causative mutation affecting expression of MUTYH

(2010) Leah S. Brault et al.   GENOMICS

Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients

(2010) Ramprasath Venkatachalam et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular Genetic Analysis of a Cell Adhesion Molecule With Homology to L1CAM, Contactin 6, and Contactin 4 Candidate Chromosome 3p26pter Tumor Suppressor Genes in Ovarian Cancer

(2010) Emily N. Manderson et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

HomozygousBUB1BMutation and Susceptibility to Gastrointestinal Neoplasia

(2010) Thomas Rio Frio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterising and Predicting Haploinsufficiency in the Human Genome

(2010) Ni Huang et al.   PLoS Genetics

MUTYH-associated polyposis

(2009) Julian R. Sampson et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Association of a Germ-Line Copy Number Variation at 2p24.3 and Risk for Aggressive Prostate Cancer

(2009) W. Liu et al.   CANCER RESEARCH

Copy number variations and cancer susceptibility

(2009) Adam Shlien et al.   CURRENT OPINION IN ONCOLOGY

Copy number variation at 1q21.1 associated with neuroblastoma

(2009) Sharon J. Diskin et al.   NATURE

Multiple Rare Nonsynonymous Variants in the Adenomatous Polyposis Coli Gene Predispose to Colorectal Adenomas

(2008) D. Azzopardi et al.   CANCER RESEARCH

Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3

(2008) A R Dallosso et al.   GUT