Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3

LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer

(2013) J Ding et al.   BRITISH JOURNAL OF CANCER

Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer

(2013) Julia Höbaus et al.   INTERNATIONAL JOURNAL OF CANCER

Methylation Status of the CpG Islands in Vitamin D and Calcium-Sensing Receptor Gene Promoters Does Not Explain the Reduced Gene Expressions in Parathyroid Adenomas

(2013) Shweta Varshney et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/β-catenin signaling, reduced non-canonical Wnt signaling and increased susceptibility to azoxymethane-induced aberrant crypt foci

(2013) R John MacLeod   LABORATORY INVESTIGATION

Calcium Nutrition and Extracellular Calcium Sensing: Relevance for the Pathogenesis of Osteoporosis, Cancer and Cardiovascular Diseases

(2013) Meinrad Peterlik et al.   Nutrients

Calcium sensing receptor signalling in physiology and cancer

(2012) Sarah C. Brennan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis

(2012) Carla Casalà et al.   CARCINOGENESIS

Review Article: Loss of the Calcium-Sensing Receptor in Colonic Epithelium is a Key Event in the Pathogenesis of Colon Cancer

(2012) Ailín C. Rogers et al.   Clinical Colorectal Cancer

Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum

(2012) Mai Yamauchi et al.   GUT

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression

(2012) Sabine Seuter et al.   NUCLEIC ACIDS RESEARCH

DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes

(2012) Eriko G. Clements et al.   NUCLEIC ACIDS RESEARCH

The Influence of Curcumin, Quercetin, and Eicosapentaenoic Acid on the Expression of Phase II Detoxification Enzymes in the Intestinal Cell Lines HT-29, Caco-2, HuTu 80, and LT97

(2012) Julia Odenthal et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

The Calcium-Sensing Receptor Beyond Extracellular Calcium Homeostasis: Conception, Development, Adult Physiology, and Disease

(2011) Daniela Riccardi et al.   Annual Review of Physiology

Negative Cross-talk between Calcium-sensing Receptor and β-Catenin Signaling Systems in Colonic Epithelium

(2011) Osvaldo Rey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis

(2011) Keiichi Hizaki et al.   MODERN PATHOLOGY

Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition

(2010) Osvaldo Rey et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effects of Vitamin D and Calcium on Proliferation and Differentiation In Normal Colon Mucosa: a Randomized Clinical Trial

(2009) V. Fedirko et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Effects of Vitamin D and Calcium Supplementation on Markers of Apoptosis in Normal Colon Mucosa: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

(2009) V. Fedirko et al.   Cancer Prevention Research

The Candidate Oncogene CYP24A1: A Potential Biomarker for Colorectal Tumorigenesis

(2009) Henrik C. Horváth et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia

(2008) Ivan I. Pacheco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Clone-specific expression, transcriptional regulation, and action of interleukin-6 in human colon carcinoma cells

(2008) Wolfgang Brozek et al.   BMC CANCER

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE