SDF-1α stiffens myeloma bone marrow mesenchymal stromal cells through the activation of RhoA-ROCK-Myosin II

International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation

(2014) Antonio Palumbo et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting the Biophysical Properties of the Myeloma Initiating Cell Niches: A Pharmaceutical Synergism Analysis Using Multi-Scale Agent-Based Modeling

(2014) Jing Su et al.   PLoS One

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

(2013) Aldo M. Roccaro et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidences of Early Senescence in Multiple Myeloma Bone Marrow Mesenchymal Stromal Cells

(2013) Thibaud André et al.   PLoS One

Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling

(2012) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Myeloma Mesenchymal Stem Cells: Characterization, Origin, and Tumor-Promoting Effects

(2011) M. R. Reagan et al.   CLINICAL CANCER RESEARCH

Multiple Myeloma

(2011) Antonio Palumbo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stable Changes in Mesenchymal Stromal Cells from Multiple Myeloma Patients Revealed through Their Responses to Toll-Like Receptor Ligands and Epidermal Growth Factor

(2011) Meirav Pevsner-Fischer et al.   Stem Cell Reviews and Reports

CXCL12 (SDF-1)/CXCR4 Pathway in Cancer

(2010) B. A. Teicher et al.   CLINICAL CANCER RESEARCH

Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

(2010) Jörg Schrader et al.   HEPATOLOGY

Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

(2010) Stephanie Markovina et al.   Molecular Cancer

Bone Marrow Stromal Cells From Myeloma Patients Support the Growth of Myeloma Stem Cells

(2010) Yongdong Feng et al.   STEM CELLS AND DEVELOPMENT

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

(2009) A. K. Azab et al.   BLOOD

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling

(2009) A. Levoye et al.   BLOOD

Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells

(2009) S. K. Martin et al.   HAEMATOLOGICA

Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells

(2009) Donny Hanjaya-Putra et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donors

(2009) M Garayoa et al.   LEUKEMIA

Unique biomechanical interactions between myeloma cells and bone marrow stroma cells

(2009) Yongdong Feng et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells

(2008) Barbara Zdzisińska et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma

(2008) J. Kirshner et al.   BLOOD

Viscoelastic behaviour of human mesenchymal stem cells

(2008) Samuel CW Tan et al.   BMC CELL BIOLOGY

Breast Carcinoma-Associated Fibroblasts and Their Counterparts Display Neoplastic-Specific Changes

(2008) N. M. Hawsawi et al.   CANCER RESEARCH

Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance

(2008) W. Matsui et al.   CANCER RESEARCH