Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma

PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer

(2013) A. Herzog et al.   CLINICAL CANCER RESEARCH

Molecular Pathways: Involving Microenvironment Damage Responses in Cancer Therapy Resistance

(2012) Y. Sun et al.   CLINICAL CANCER RESEARCH

Genetic Variants in the PI3K/PTEN/AKT/mTOR Pathway Predict Head and Neck Cancer Patient Second Primary Tumor/Recurrence Risk and Response to Retinoid Chemoprevention

(2012) M. A. T. Hildebrandt et al.   CLINICAL CANCER RESEARCH

Alteration of Cellular Behavior and Response to PI3K Pathway Inhibition by Culture in 3D Collagen Gels

(2012) Brian Fallica et al.   PLoS One

Radioresistance of glioma stem cells: Intrinsic characteristic or property of the ‘microenvironment-stem cell unit’?

(2011) Mariella Mannino et al.   Molecular Oncology

EGFR–PI3K–AKT–mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapy

(2010) Christian Freudlsperger et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Tumor-Host Interactions: A Far-Reaching Relationship

(2010) Sandra S. McAllister et al.   JOURNAL OF CLINICAL ONCOLOGY

Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors

(2010) V. Vaira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma

(2009) B. Mukherjee et al.   CANCER RESEARCH

The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia

(2009) N Gallay et al.   LEUKEMIA

Cancer and the tumor microenvironment: a review of an essential relationship

(2008) Flaubert Mbeunkui et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

EGFR inhibition as a therapy for head and neck squamous cell carcinoma

(2008) Judith Loeffler-Ragg et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

(2008) Johan Bussink et al.   LANCET ONCOLOGY

Dysregulated molecular networks in head and neck carcinogenesis

(2008) Alfredo A. Molinolo et al.   ORAL ONCOLOGY

Development of an in Vitro Multicellular Tumor Spheroid Model Using Microencapsulation and Its Application in Anticancer Drug Screening and Testing

(2005) Xulang Zhang et al.   BIOTECHNOLOGY PROGRESS