Activating adaptive cellular mechanisms of resistance following sublethal cytotoxic chemotherapy: Implications for diagnostic microdosing

Toward Prediction of Efficacy of Chemotherapy: A Proof of Concept Study in Lung Cancer Patients Using [11C]docetaxel and Positron Emission Tomography

(2013) A. A. M. van der Veldt et al.   CLINICAL CANCER RESEARCH

Phase 0 Microdosing PET Study Using the Human Mini Antibody F16SIP in Head and Neck Cancer Patients

(2013) D. A. Heuveling et al.   JOURNAL OF NUCLEAR MEDICINE

Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden

(2013) Khalid Abubaker et al.   Molecular Cancer

Personalized medicine for targeted and platinum-based chemotherapy of lung and bladder cancer

(2013) George D Cimino et al.   Bioanalysis

Knock-down of NDRG2 sensitizes cervical cancer Hela cells to cisplatin through suppressing Bcl-2 expression

(2012) Junye Liu et al.   BMC CANCER

Role of the Human High-Affinity Copper Transporter in Copper Homeostasis Regulation and Cisplatin Sensitivity in Cancer Chemotherapy

(2012) M. T. Kuo et al.   CANCER RESEARCH

Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling

(2012) Y.-P. Liu et al.   CANCER RESEARCH

Subpopulation of small-cell lung cancer cells expressing CD133 and CD87 show resistance to chemotherapy

(2012) Toshio Kubo et al.   CANCER SCIENCE

Predicting Drug Candidate Victims of Drug-Drug Interactions, using Microdosing

(2012) Marie Croft et al.   CLINICAL PHARMACOKINETICS

Membrane Transporters as Determinants of the Pharmacology of Platinum Anticancer Drugs

(2012) Johnson J. Liu et al.   CURRENT CANCER DRUG TARGETS

Cellular senescence and cancer chemotherapy resistance

(2012) Ryan R. Gordon et al.   DRUG RESISTANCE UPDATES

Tissue Platinum Concentration and Tumor Response in Non–Small-Cell Lung Cancer

(2012) Eric S. Kim et al.   JOURNAL OF CLINICAL ONCOLOGY

Microdosing: A Critical Assessment of Human Data

(2012) Malcolm Rowland   JOURNAL OF PHARMACEUTICAL SCIENCES

Purification and biochemical characterization of a novel protein—tongue cancer chemotherapy resistance-associated protein1 (TCRP1)

(2012) Bo Peng et al.   PROTEIN EXPRESSION AND PURIFICATION

Cytoplasmic p21 is a potential predictor for cisplatin sensitivity in ovarian cancer

(2011) Xi Xia et al.   BMC CANCER

Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma

(2011) M Yamasaki et al.   BRITISH JOURNAL OF CANCER

DNA Repair Capacity in Peripheral Lymphocytes Predicts Survival of Patients With Non–Small-Cell Lung Cancer Treated With First-Line Platinum-Based Chemotherapy

(2011) Li-E Wang et al.   JOURNAL OF CLINICAL ONCOLOGY

TCRP1 promotes radioresistance of oral squamous cell carcinoma cells via Akt signal pathway

(2011) Yixue Gu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Cisplatin transiently up-regulates hHR23 expression through enhanced translational efficiency in A549 adenocarcinoma cells

(2011) Yu-Han Shen et al.   TOXICOLOGY LETTERS

Comparative requirements for exploratory clinical trials — eIND, eCTA and microdosing

(2010) Patrick Y. Muller   ADVANCED DRUG DELIVERY REVIEWS

A new step ahead for the consideration of ERCC1 as a candidate biomarker to select NSCLC patients for the treatment of cetuximab in combination with cisplatin

(2010) Ken André Olaussen   CANCER BIOLOGY & THERAPY

Genetic modifiers of carcinogen DNA adducts in target lung and peripheral blood mononuclear cells

(2010) M.-S. Lee et al.   CARCINOGENESIS

A microdosing approach for characterizing formation and repair of carboplatin-DNA monoadducts and chemoresistance

(2010) Paul T. Henderson et al.   INTERNATIONAL JOURNAL OF CANCER

The therapeutic promise of the cancer stem cell concept

(2010) Natasha Y. Frank et al.   JOURNAL OF CLINICAL INVESTIGATION

Human microdosing for the prediction of patient response

(2010) Paul T Henderson et al.   Bioanalysis

Microdosing: current and the future

(2010) Graham Lappin   Bioanalysis

Restriction of cisplatin induction of acute apoptosis to a subpopulation of cells in a three-dimensional carcinoma culture model

(2009) Walid Fayad et al.   INTERNATIONAL JOURNAL OF CANCER

Repeated Treatment with Subtoxic Doses of TRAIL Induces Resistance to Apoptosis through Its Death Receptors in MDA-MB-231 Breast Cancer Cells

(2009) T. Yoshida et al.   MOLECULAR CANCER RESEARCH

Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers

(2009) M. Santarosa et al.   MOLECULAR CANCER THERAPEUTICS

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-performance liquid chromatography accelerator mass spectrometry: Correcting for losses during analysis by internal standardization

(2008) G. Lappin et al.   ANALYTICAL BIOCHEMISTRY

Subattomole Sensitivity in Biological Accelerator Mass Spectrometry

(2008) Mehran Salehpour et al.   ANALYTICAL CHEMISTRY

Platinum Resistance: The Role of DNA Repair Pathways

(2008) L. P. Martin et al.   CLINICAL CANCER RESEARCH

The utility of microdosing over the past 5 years

(2008) Graham Lappin et al.   Expert Opinion on Drug Metabolism & Toxicology

Immunohistochemical expression of BCRP and ERCC1 in biopsy specimen predicts survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy

(2008) Shuji Ota et al.   LUNG CANCER

The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy

(2007) Matthew D. Hall et al.   Annual Review of Pharmacology and Toxicology