Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma

Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motilityin vitroand drives tumor formationin vivo

(2013) Yuhki Yokoyama et al.   CANCER SCIENCE

Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice

(2013) Grace Chappell et al.   INTERNATIONAL JOURNAL OF CANCER

Improved Therapeutic Effect against Leukemia by a Combination of the Histone Methyltransferase Inhibitor Chaetocin and the Histone Deacetylase Inhibitor Trichostatin A

(2013) Huong Thi Thanh Tran et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

On the Histone Lysine Methyltransferase Activity of Fungal Metabolite Chaetocin

(2013) Fanny L. Cherblanc et al.   JOURNAL OF MEDICINAL CHEMISTRY

Role of Histone Lysine Methyltransferases SUV39H1 and SETDB1 in Gliomagenesis: Modulation of Cell Proliferation, Migration, and Colony Formation

(2013) Anastasia Spyropoulou et al.   NEUROMOLECULAR MEDICINE

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

(2013) M Rodriguez-Paredes et al.   ONCOGENE

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Histone lysine methyltransferase, suppressor of variegation 3-9 homolog 1, promotes hepatocellular carcinoma progression and is negatively regulated by microRNA-125b

(2012) Dorothy Ngo-Yin Fan et al.   HEPATOLOGY

Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer

(2012) C Dong et al.   ONCOGENE

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells

(2011) Tetsuhiro Chiba et al.   INTERNATIONAL JOURNAL OF CANCER

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

(2011) Craig J. Ceol et al.   NATURE

Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro

(2010) Yoon-Mi Lee et al.   HEPATOLOGY

A Subset of the Histone H3 Lysine 9 Methyltransferases Suv39h1, G9a, GLP, and SETDB1 Participate in a Multimeric Complex

(2010) Lauriane Fritsch et al.   MOLECULAR CELL

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

The Histone Demethylase RBP2 Is Overexpressed in Gastric Cancer and Its Inhibition Triggers Senescence of Cancer Cells

(2009) Jiping Zeng et al.   GASTROENTEROLOGY

Distinct expression of polycomb group proteins EZH2 and BMI1 in hepatocellular carcinoma

(2009) Yutaka Yonemitsu et al.   HUMAN PATHOLOGY

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition

(2009) A Lakshmikuttyamma et al.   ONCOGENE

The Global Histone Modification Pattern Correlates with Cancer Recurrence and Overall Survival in Gastric Adenocarcinoma

(2008) Young Soo Park et al.   ANNALS OF SURGICAL ONCOLOGY

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE