Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency

A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention

(2013) Roland Rad et al.   CANCER CELL

Expression of MUC2, MUC5AC, MUC5B and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype

(2013) Michael D Walsh et al.   MODERN PATHOLOGY

Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions

(2013) Felipe De Sousa E Melo et al.   NATURE MEDICINE

Colorectal cancer: a tale of two sides or a continuum?: Figure 1

(2012) Mai Yamauchi et al.   GUT

Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer

(2012) Sae-Won Han et al.   INTERNATIONAL JOURNAL OF CANCER

Proposal for a 10-high-power-fields scoring method for the assessment of tumor budding in colorectal cancer

(2012) Eva Karamitopoulou et al.   MODERN PATHOLOGY

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Stratification and Prognostic Relevance of Jass’s Molecular Classification of Colorectal Cancer

(2012) Inti Zlobec et al.   Frontiers in Oncology

The CpG island methylator phenotype may confer a survival benefit in patients with stage II or III colorectal carcinomas receiving fluoropyrimidine-based adjuvant chemotherapy

(2011) Byung-Hoon Min et al.   BMC CANCER

Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features

(2011) Inti Zlobec et al.   JOURNAL OF PATHOLOGY

Up and downregulation of p16Ink4a expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer

(2011) Lydia Kriegl et al.   MODERN PATHOLOGY

Differential clinicopathological features in microsatellite instability-positive colorectal cancers depending on CIMP status

(2011) Jeong Mo Bae et al.   VIRCHOWS ARCHIV

The Role of the CpG Island Methylator Phenotype in Colorectal Cancer Prognosis Depends on Microsatellite Instability Screening Status

(2010) A. M. Dahlin et al.   CLINICAL CANCER RESEARCH

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation ofp16INK4a

(2010) Linda A. S. Carragher et al.   EMBO Molecular Medicine

Role of the Serrated Pathway in Colorectal Cancer Pathogenesis

(2010) Barbara Leggett et al.   GASTROENTEROLOGY

5-Fluorouracil Adjuvant Chemotherapy Does Not Increase Survival in Patients With CpG Island Methylator Phenotype Colorectal Cancer

(2010) Rodrigo Jover et al.   GASTROENTEROLOGY

Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer

(2010) Eva Karamitopoulou et al.   HISTOPATHOLOGY

Combined analysis of specific KRAS mutation, BRAF and microsatellite instability identifies prognostic subgroups of sporadic and hereditary colorectal cancer

(2010) Inti Zlobec et al.   INTERNATIONAL JOURNAL OF CANCER

Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review

(2010) Kaori Shima et al.   INTERNATIONAL JOURNAL OF CANCER

Sessile serrated adenomas and classical adenomas: An epigenetic perspective on premalignant neoplastic lesions of the gastrointestinal tract

(2010) Mashaal Dhir et al.   INTERNATIONAL JOURNAL OF CANCER

Relationship of CDX2 Loss with Molecular Features and Prognosis in Colorectal Cancer

(2009) Y. Baba et al.   CLINICAL CANCER RESEARCH

Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers

(2009) Jung Ho Kim et al.   VIRCHOWS ARCHIV

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

(2008) S. Ogino et al.   GUT

Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients: is the CpG island methylator phenotype the 5-fluorouracilresponsive subgroup?

(2008) Barry Iacopetta et al.   International Journal of Clinical Oncology

Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status

(2008) Alessandro Lugli et al.   MODERN PATHOLOGY